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1000 Titel
  • Urinary excretions of 34 dietary polyphenols and their associations with lifestyle factors in the EPIC cohort study
1000 Autor/in
  1. Zamora-Ros, Raul |
  2. Achaintre, David |
  3. Rothwell, Joseph A. |
  4. Rinaldi, Sabina |
  5. Assi, Nada |
  6. Ferrari, Pietro |
  7. Leitzmann, Michael |
  8. Boutron-Ruault, Marie-Christine |
  9. Fagherazzi, Guy |
  10. Auffret, Aurélie |
  11. Kühn, Tilman |
  12. Katzke, Verena |
  13. Böing, Heiner |
  14. Trichopoulou, Antonia |
  15. Naska, Androniki |
  16. Vasilopoulou, Effie |
  17. Palli, Domenico |
  18. Grioni, Sara |
  19. Mattiello, Amalia |
  20. Tumino, Rosario |
  21. Ricceri, Fulvio |
  22. Slimani, Nadia |
  23. Romieu, Isabelle |
  24. Scalbert, Augustin |
1000 Erscheinungsjahr 2016
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2016-06-07
1000 Erschienen in
1000 Quellenangabe
  • 6:26905
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2016
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.1038/srep26905 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895229/ |
1000 Ergänzendes Material
  • http://www.nature.com/articles/srep26905#supplementary-information |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Urinary excretion of 34 dietary polyphenols and their variations according to diet and other lifestyle factors were measured by tandem mass spectrometry in 475 adult participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) cross-sectional study. A single 24-hour urine sample was analysed for each subject from 4 European countries. The highest median levels were observed for phenolic acids such as 4-hydroxyphenylacetic acid (157 μmol/24 h), followed by 3-hydroxyphenylacetic, ferulic, vanillic and homovanillic acids (20-50 μmol/24 h). The lowest concentrations were observed for equol, apigenin and resveratrol (<0.1 μmol/24 h). Urinary polyphenols significantly varied by centre, followed by alcohol intake, sex, educational level, and energy intake. This variability is largely explained by geographical variations in the diet, as suggested by the high correlations (r > 0.5) observed between urinary polyphenols and the intake of their main food sources (e.g., resveratrol and gallic acid ethyl ester with red wine intake; caffeic, protocatechuic and ferulic acids with coffee consumption; and hesperetin and naringenin with citrus fruit intake). The large variations in urinary polyphenols observed are largely determined by food preferences. These polyphenol biomarkers should allow more accurate evaluation of the relationships between polyphenol exposure and the risk of chronic diseases in large epidemiological studies.
1000 Sacherschließung
lokal Epidemology
lokal Predictive markers
1000 Fachgruppe
  1. Medizin |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/WmFtb3JhLVJvcywgUmF1bA==|https://frl.publisso.de/adhoc/creator/QWNoYWludHJlLCBEYXZpZA==|https://frl.publisso.de/adhoc/creator/Um90aHdlbGwsIEpvc2VwaCBBLg==|https://frl.publisso.de/adhoc/creator/UmluYWxkaSwgU2FiaW5h|https://frl.publisso.de/adhoc/creator/QXNzaSwgTmFkYQ==|https://frl.publisso.de/adhoc/creator/RmVycmFyaSwgUGlldHJv|https://frl.publisso.de/adhoc/creator/TGVpdHptYW5uLCBNaWNoYWVs|https://frl.publisso.de/adhoc/creator/Qm91dHJvbi1SdWF1bHQsIE1hcmllLUNocmlzdGluZQ==|https://frl.publisso.de/adhoc/creator/RmFnaGVyYXp6aSwgR3V5|https://frl.publisso.de/adhoc/creator/QXVmZnJldCwgQXVyw6lsaWU=|https://frl.publisso.de/adhoc/creator/S8O8aG4sIFRpbG1hbg==|https://frl.publisso.de/adhoc/creator/S2F0emtlLCBWZXJlbmE=|http://d-nb.info/gnd/1111919534|https://frl.publisso.de/adhoc/creator/VHJpY2hvcG91bG91LCBBbnRvbmlh|https://frl.publisso.de/adhoc/creator/TmFza2EsIEFuZHJvbmlraQ==|https://frl.publisso.de/adhoc/creator/VmFzaWxvcG91bG91LCBFZmZpZQ==|https://frl.publisso.de/adhoc/creator/UGFsbGksIERvbWVuaWNv|https://frl.publisso.de/adhoc/creator/R3Jpb25pLCBTYXJh|https://frl.publisso.de/adhoc/creator/TWF0dGllbGxvLCBBbWFsaWE=|https://frl.publisso.de/adhoc/creator/VHVtaW5vLCBSb3Nhcmlv|https://frl.publisso.de/adhoc/creator/UmljY2VyaSwgRnVsdmlv|https://frl.publisso.de/adhoc/creator/U2xpbWFuaSwgTmFkaWE=|https://frl.publisso.de/adhoc/creator/Um9taWV1LCBJc2FiZWxsZQ==|https://frl.publisso.de/adhoc/creator/U2NhbGJlcnQsIEF1Z3VzdGlu
1000 Label
1000 Förderer
  1. Institut National du Cancer, Paris ((INCa) |
  2. Wereld Kanker Onderzoek Fonds (WCRF NL) |
  3. Ligue contre le Cancer |
  4. Institut Gustave Roussy |
  5. Mutuelle Générale de l’Education Nationale |
  6. Institut National de la Santé et de la Recherche Médicale (INSERM) |
  7. German Cancer Aid |
  8. German Cancer Research Center (DKFZ) |
  9. German Federal Ministry of Education and Research |
  10. Hellenic Health Foundation |
  11. Italian Association for Research on Cancer (AIRC) |
  12. International Agency for Research on Cancer |
1000 Fördernummer
  1. 2011-105; 2009-139
  2. 2012/604
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1000 Förderprogramm
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  12. Senior Visiting Scientist Award
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Institut National du Cancer, Paris ((INCa) |
    1000 Förderprogramm -
    1000 Fördernummer 2011-105; 2009-139
  2. 1000 joinedFunding-child
    1000 Förderer Wereld Kanker Onderzoek Fonds (WCRF NL) |
    1000 Förderprogramm -
    1000 Fördernummer 2012/604
  3. 1000 joinedFunding-child
    1000 Förderer Ligue contre le Cancer |
    1000 Förderprogramm -
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer Institut Gustave Roussy |
    1000 Förderprogramm -
    1000 Fördernummer -
  5. 1000 joinedFunding-child
    1000 Förderer Mutuelle Générale de l’Education Nationale |
    1000 Förderprogramm -
    1000 Fördernummer -
  6. 1000 joinedFunding-child
    1000 Förderer Institut National de la Santé et de la Recherche Médicale (INSERM) |
    1000 Förderprogramm -
    1000 Fördernummer -
  7. 1000 joinedFunding-child
    1000 Förderer German Cancer Aid |
    1000 Förderprogramm -
    1000 Fördernummer -
  8. 1000 joinedFunding-child
    1000 Förderer German Cancer Research Center (DKFZ) |
    1000 Förderprogramm -
    1000 Fördernummer -
  9. 1000 joinedFunding-child
    1000 Förderer German Federal Ministry of Education and Research |
    1000 Förderprogramm -
    1000 Fördernummer -
  10. 1000 joinedFunding-child
    1000 Förderer Hellenic Health Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
  11. 1000 joinedFunding-child
    1000 Förderer Italian Association for Research on Cancer (AIRC) |
    1000 Förderprogramm -
    1000 Fördernummer -
  12. 1000 joinedFunding-child
    1000 Förderer International Agency for Research on Cancer |
    1000 Förderprogramm Senior Visiting Scientist Award
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6403845.rdf
1000 Erstellt am 2017-08-14T11:53:24.926+0200
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1000 Bearbeitet von 25
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