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WeightNameValue
1000 Titel
  • Immediate and long-term transcriptional response of hind muscle tissue to transient variation of incubation temperature in broilers
1000 Autor/in
  1. Naraballobh, Watcharapong |
  2. Trakooljul, Nares |
  3. Muráni, Eduard |
  4. Brunner, Ronald |
  5. Krischek, Carsten |
  6. Janisch, Sabine |
  7. Wicke, Michael |
  8. Ponsuksili, Siriluck |
  9. Wimmers, Klaus |
1000 Erscheinungsjahr 2016
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2016-05-24
1000 Erschienen in
1000 Quellenangabe
  • 17:323
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2016
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1186/s12864-016-2671-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855815/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: In oviparous species accidental variation of incubation temperatures may occur under natural conditions and mechanisms may have evolved by natural selection that facilitate coping with these stressors. However, under controlled artificial incubation modification of egg incubation temperature has been shown to have a wide-ranging impact on post-hatch development in several poultry species. Because developmental changes initiated in-ovo can affect poultry production, understanding the molecular routes and epigenetic alterations induced by incubation temperature differences may allow targeted modification of phenotypes. RESULTS: In order to identify molecular pathways responsive to variable incubation temperature, broiler eggs were incubated at a lower or higher temperature (36.8 °C, 38.8 °C) relative to control (37.8 °C) over two developmental intervals, embryonic days (E) 7–10 and 10–13. Global gene expression of M. gastrocnemius was assayed at E10, E13, and slaughter age [post-hatch day (D) 35] (6 groups; 3 time points; 8 animals each) by microarray analysis and treated samples were compared to controls within each time point. Transcript abundance differed for between 113 and 738 genes, depending on treatment group, compared to the respective control. In particular, higher incubation temperature during E7-10 immediately affected pathways involved in energy and lipid metabolism, cell signaling, and muscle development more so than did other conditions. But lower incubation temperature during E10-13 affected pathways related to cellular function and growth, and development of organ, tissue, and muscle as well as nutrient metabolism pathways at D35. CONCLUSION: Shifts in incubation temperature provoke specific immediate and long-term transcriptional responses. Further, the transcriptional response to lower incubation temperature, which did not affect the phenotypes, mediates compensatory effects reflecting adaptability. In contrast, higher incubation temperature triggers gene expression and has long-term effects on the phenotype, reflecting considerable phenotypic plasticity. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-016-2671-9) contains supplementary material, which is available to authorized users.
1000 Sacherschließung
lokal Pathway analysis
lokal Poultry
lokal Gene expression
lokal Microarray
lokal In-ovo development
1000 Fachgruppe
  1. Agrarwissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/TmFyYWJhbGxvYmgsIFdhdGNoYXJhcG9uZw==|https://frl.publisso.de/adhoc/creator/VHJha29vbGp1bCwgTmFyZXM=|https://frl.publisso.de/adhoc/creator/TXVyw6FuaSwgRWR1YXJk|https://frl.publisso.de/adhoc/creator/QnJ1bm5lciwgUm9uYWxk|https://frl.publisso.de/adhoc/creator/S3Jpc2NoZWssIENhcnN0ZW4=|https://frl.publisso.de/adhoc/creator/SmFuaXNjaCwgU2FiaW5l|https://frl.publisso.de/adhoc/creator/V2lja2UsIE1pY2hhZWw=|https://frl.publisso.de/adhoc/creator/UG9uc3Vrc2lsaSwgU2lyaWx1Y2s=|http://orcid.org/0000-0002-9523-6790
1000 Förderer
  1. German Research Foundation (DFG) |
1000 Fördernummer
  1. WE 4079/4-1; WI 1754/15-1; WI 2072/9-1
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Research Foundation (DFG) |
    1000 Förderprogramm -
    1000 Fördernummer WE 4079/4-1; WI 1754/15-1; WI 2072/9-1
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6403910.rdf
1000 Erstellt am 2017-08-16T10:26:40.532+0200
1000 Erstellt von 122
1000 beschreibt frl:6403910
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Fri Jul 13 12:21:50 CEST 2018
1000 Objekt bearb. Fri Jul 13 12:21:49 CEST 2018
1000 Vgl. frl:6403910
1000 Oai Id
  1. oai:frl.publisso.de:frl:6403910 |
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