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WeightNameValue
1000 Titel
  • Sex reversal assessments reveal different vulnerability to endocrine disruption between deeply diverged anuran lineages
1000 Autor/in
  1. Tamschick, Stephanie |
  2. Rozenblut-Kościsty, Beata |
  3. Ogielska, Maria |
  4. Lehmann, Andreas |
  5. Lymberakis, Petros |
  6. Hoffmann, Frauke |
  7. Lutz, Ilka |
  8. Kloas, Werner |
  9. Stöck, Matthias |
1000 Erscheinungsjahr 2016
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2016-03-31
1000 Erschienen in
1000 Quellenangabe
  • 6: 23825
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2016
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.1038/srep23825 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814869/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/srep23825#supplementary-information |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Multiple anthropogenic stressors cause worldwide amphibian declines. Among several poorly investigated causes is global pollution of aquatic ecosystems with endocrine disrupting compounds (EDCs). These substances interfere with the endocrine system and can affect the sexual development of vertebrates including amphibians. We test the susceptibility to an environmentally relevant contraceptive, the artificial estrogen 17α-ethinylestradiol (EE2), simultaneously in three deeply divergent systematic anuran families, a model-species, Xenopus laevis (Pipidae), and two non-models, Hyla arborea (Hylidae) and Bufo viridis (Bufonidae). Our new approach combines synchronized tadpole exposure to three EE2-concentrations (50, 500, 5,000 ng/L) in a flow-through-system and pioneers genetic and histological sexing of metamorphs in non-model anurans for EDC-studies. This novel methodology reveals striking quantitative differences in genetic-male-to-phenotypic-female sex reversal in non-model vs. model species. Our findings qualify molecular sexing in EDC-analyses as requirement to identify sex reversals and state-of-the-art approaches as mandatory to detect species-specific vulnerabilities to EDCs in amphibians.
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/VGFtc2NoaWNrLCBTdGVwaGFuaWU=|https://frl.publisso.de/adhoc/creator/Um96ZW5ibHV0LUtvxZtjaXN0eSzCoEJlYXRh|https://frl.publisso.de/adhoc/creator/T2dpZWxza2EswqBNYXJpYQ==|https://frl.publisso.de/adhoc/creator/TGVobWFubizCoEFuZHJlYXM=|https://frl.publisso.de/adhoc/creator/THltYmVyYWtpcyzCoFBldHJvcw==|https://frl.publisso.de/adhoc/creator/SG9mZm1hbm4swqBGcmF1a2U=|https://frl.publisso.de/adhoc/creator/THV0eizCoElsa2E=|https://frl.publisso.de/adhoc/creator/S2xvYXMswqBXZXJuZXI=|http://orcid.org/0000-0003-4888-8371
1000 Label
1000 Förderer
  1. German Science Foundation (DFG) |
  2. - |
  3. Leibniz Association |
1000 Fördernummer
  1. Sto 493/3-1
  2. Sto 493/2-1; Sto 493/2-2
  3. -
1000 Förderprogramm
  1. -
  2. Heisenberg-Fellowship
  3. Open Access Fund
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Science Foundation (DFG) |
    1000 Förderprogramm -
    1000 Fördernummer Sto 493/3-1
  2. 1000 joinedFunding-child
    1000 Förderer - |
    1000 Förderprogramm Heisenberg-Fellowship
    1000 Fördernummer Sto 493/2-1; Sto 493/2-2
  3. 1000 joinedFunding-child
    1000 Förderer Leibniz Association |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6404266.rdf
1000 Erstellt am 2017-09-04T09:05:00.059+0200
1000 Erstellt von 218
1000 beschreibt frl:6404266
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Mon Dec 07 18:25:34 CET 2020
1000 Objekt bearb. Mon Dec 07 18:25:34 CET 2020
1000 Vgl. frl:6404266
1000 Oai Id
  1. oai:frl.publisso.de:frl:6404266 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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