Download
Ahrens-et-al_2014_Metabolic syndrome in young children.pdf 520,33KB
WeightNameValue
1000 Titel
  • Metabolic syndrome in young children: definitions and results of the IDEFICS study
1000 Autor/in
  1. Ahrens, Wolfgang |
  2. Moreno, Luis A. |
  3. Marild, Staffan |
  4. Molnar, Dénes |
  5. Siani, Alfonso |
  6. De Henauw, Stefaan |
  7. Böhmann, Johann |
  8. Günther, Kathrin |
  9. Hadjigeorgiou, Charalampos |
  10. Iacoviello, Licia |
  11. Lissner, Lauren |
  12. Veidebaum, Toomas |
  13. Pohlabeln, Hermann |
  14. Pigeot, Iris |
1000 Mitwirkende/r
  1. The IDEFICS consortium |
1000 Erscheinungsjahr 2014
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2014-09-15
1000 Erschienen in
1000 Quellenangabe
  • 38: S4-S14
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2014
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1038/ijo.2014.130 |
1000 Ergänzendes Material
  • https://www.nature.com/articles/ijo2014130#appendices |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • OBJECTIVE: To estimate the prevalence of the metabolic syndrome (MetS) using reference standards obtained in European children and to develop a quantitative MetS score and describe its distribution in children. DESIGN AND METHODS: Population-based survey in eight European countries, including 18745 children 2.0 to 10.9 years, recruited during a second survey. Anthropometry (weight, height and waist circumference), blood pressure and serum-fasting triglycerides, HDL cholesterol, glucose and insulin were measured. We applied three widely accepted definitions of the pediatric MetS and we suggest a new definition, to guide pediatricians in decisions about close monitoring or even intervention (values of at least three of the MetS components exceeding the 90th or 95th percentile, respectively). We used a z-score standardisation to calculate a continuous score combining the MetS components. RESULTS: Among the various definitions of MetS, the highest prevalence (5.5%) was obtained with our new definition requiring close observation (monitoring level). Our more conservative definition, requiring pediatric intervention gives a prevalence of 1.8%. In general, prevalences were higher in girls than in boys. The prevalence of metabolic syndrome is highest among obese children. All definitions classify a small percentage of thin or normal weight children as being affected. The metabolic syndrome score shows a positive trend with age, particularly regarding the upper percentiles of the score. CONCLUSIONS: According to different definitions of pediatric MetS, a non-negligible proportion of mostly prepubertal children are classified as affected. We propose a new definition of MetS that should improve clinical guidance. The continuous score developed may also serve as a useful tool in pediatric obesity research. It has to be noted, however, that the proposed cutoffs are based on a statistical definition that does not yet allow to quantify the risk of subsequent disease.
1000 Sacherschließung
lokal Metabolic syndrome
lokal Epidemiology
lokal Paediatrics
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. http://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/creator/TW9yZW5vLCBMdWlzIEEu|https://frl.publisso.de/adhoc/creator/TWFyaWxkLCBTdGFmZmFu|https://frl.publisso.de/adhoc/creator/TW9sbmFyLCBEw6luZXM=|https://frl.publisso.de/adhoc/creator/U2lhbmksIEFsZm9uc28=|https://frl.publisso.de/adhoc/creator/RGUgSGVuYXV3LCBTdGVmYWFu|https://frl.publisso.de/adhoc/creator/QsO2aG1hbm4sIEpvaGFubg==|https://frl.publisso.de/adhoc/creator/R8O8bnRoZXIsIEthdGhyaW4=|https://frl.publisso.de/adhoc/creator/SGFkamlnZW9yZ2lvdSwgQ2hhcmFsYW1wb3M=|https://frl.publisso.de/adhoc/creator/SWFjb3ZpZWxsbywgTGljaWE=|https://frl.publisso.de/adhoc/creator/TGlzc25lciwgTGF1cmVu|https://frl.publisso.de/adhoc/creator/VmVpZGViYXVtLCBUb29tYXM=|http://orcid.org/0000-0002-9575-1119|http://orcid.org/0000-0001-7483-0726|https://frl.publisso.de/adhoc/corporateBody/VGhlIElERUZJQ1MgY29uc29ydGl1bQ==
1000 Förderer
  1. European Community |
  2. Volkswagen Foundation |
  3. The Swedish Research Council (VR) |
  4. FORTE |
  5. FORMAS |
1000 Fördernummer
  1. 016181 (FOOD)
  2. -
  3. -
  4. -
  5. -
1000 Förderprogramm
  1. Sixth Framework Programme
  2. -
  3. -
  4. -
  5. -
1000 Dateien
  1. Metabolic syndrome in young children: definitions and results of the IDEFICS study
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Community |
    1000 Förderprogramm Sixth Framework Programme
    1000 Fördernummer 016181 (FOOD)
  2. 1000 joinedFunding-child
    1000 Förderer Volkswagen Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
  3. 1000 joinedFunding-child
    1000 Förderer The Swedish Research Council (VR) |
    1000 Förderprogramm -
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer FORTE |
    1000 Förderprogramm -
    1000 Fördernummer -
  5. 1000 joinedFunding-child
    1000 Förderer FORMAS |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6407094.rdf
1000 Erstellt am 2018-03-13T13:33:19.202+0100
1000 Erstellt von 266
1000 beschreibt frl:6407094
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Tue May 29 12:00:06 CEST 2018
1000 Objekt bearb. Tue May 29 12:00:05 CEST 2018
1000 Vgl. frl:6407094
1000 Oai Id
  1. oai:frl.publisso.de:frl:6407094 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source