Download
De Henauw-et-al_2014_Blood lipids among young children.pdf 926,24KB
WeightNameValue
1000 Titel
  • Blood lipids among young children in Europe: results from the European IDEFICS study
1000 Autor/in
  1. De Henauw, Stefaan |
  2. Michels, Nathalie |
  3. Vyncke, Krishna |
  4. Hebestreit, Antje |
  5. Russo, Paola |
  6. Intemann, Timm |
  7. Peplies, Jenny |
  8. Fraterman, Arno |
  9. Eiben, Gabriele |
  10. De Lorgeril, Michel |
  11. Tornaritis, Michael |
  12. Molnar, Dénes |
  13. Veidebaum, Toomas |
  14. Ahrens, Wolfgang |
  15. Moreno, Luis A. |
1000 Mitwirkende/r
  1. The IDEFICS consortium |
1000 Erscheinungsjahr 2014
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2014-09-15
1000 Erschienen in
1000 Quellenangabe
  • 38: S67-S75
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2014
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1038/ijo.2014.137 |
1000 Ergänzendes Material
  • https://www.nature.com/articles/ijo2014137#supplementary-information |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Measurement of cholesterol and triglyceride (TG) fractions in blood has become standard practice in the early detection of atherosclerotic disease pathways. Considerable attention is given nowadays to the presence of these risk factors in children and to start preventive campaigns early in life. In this context, it is imperative to have valid comparative frameworks for interpretation of lipid levels. The aim of this study is to present sex- and age-specific reference values on blood lipid levels in European children aged 2.0–10.9 years. METHODS: Fasting blood was obtained via either venipuncture or capillary sampling. In 13 579 European non-obese children (50.3% boys), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), TG and TC/HDL-C ratio levels were measured with a point-of-care analyser (Cholestech). Sex- and age-specific reference values were computed with the GAMLSS method with the statistical software R. RESULTS: Reference curves and 1st, 3rd, 10th, 25th, 50th, 75th, 90th, 97th and 99th percentile values are presented. HDL-C showed a positive trend with age, from 2 years onwards, but was relatively stable above the age of 7. For LDL-C and TC, linear but small age-related trends were seen. The TC/HDL-C values showed a gradual negative trend from the age of 2 up to 6 and were relatively stable afterwards. For TG, no age trend was found (P=0.285). Boys had higher mean HDL-C values than girls (1.414 vs 1.368 mmol l−1), and lower TC, LDL-C, TC/HDL-C and TG values (3.981 vs 4.087 mmol l−1; 2.297 vs 2.435 mmol l−1; 2.84 vs 3.01mmol l−1;  and 0.509 vs 0.542 mmol l−1, respectively). CONCLUSIONS: These new and recent references could serve as a European orientation of blood lipid values in children in the context of standard medical practice and for the purpose of public health screening.
1000 Sacherschließung
lokal Atherosclerosis
lokal Lipids
lokal Epidemiology
lokal Paediatrics
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/RGUgSGVuYXV3LCBTdGVmYWFu|https://frl.publisso.de/adhoc/creator/TWljaGVscywgTmF0aGFsaWU=|https://frl.publisso.de/adhoc/creator/VnluY2tlLCBLcmlzaG5h|http://orcid.org/0000-0001-7354-5958|https://frl.publisso.de/adhoc/creator/UnVzc28sIFBhb2xh|https://frl.publisso.de/adhoc/creator/SW50ZW1hbm4sIFRpbW0=|https://frl.publisso.de/adhoc/creator/UGVwbGllcywgSmVubnk=|https://frl.publisso.de/adhoc/creator/RnJhdGVybWFuLCBBcm5v|https://frl.publisso.de/adhoc/creator/RWliZW4sIEdhYnJpZWxl|https://frl.publisso.de/adhoc/creator/RGUgTG9yZ2VyaWwsIE1pY2hlbA==|https://frl.publisso.de/adhoc/creator/VG9ybmFyaXRpcywgTWljaGFlbA==|https://frl.publisso.de/adhoc/creator/TW9sbmFyLCBEw6luZXM=|https://frl.publisso.de/adhoc/creator/VmVpZGViYXVtLCBUb29tYXM=|http://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/creator/TW9yZW5vLCBMdWlzIEEu|https://frl.publisso.de/adhoc/corporateBody/VGhlIElERUZJQ1MgY29uc29ydGl1bQ==
1000 Förderer
  1. European Community |
  2. Volkswagen Foundation |
  3. Barilla & Co |
  4. European Commission (ATHENA) |
1000 Fördernummer
  1. 016181 (FOOD)
  2. -
  3. -
  4. -
1000 Förderprogramm
  1. Sixth Framework Programme
  2. -
  3. -
  4. -
1000 Dateien
  1. Blood lipids among young children in Europe: results from the European IDEFICS study
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Community |
    1000 Förderprogramm Sixth Framework Programme
    1000 Fördernummer 016181 (FOOD)
  2. 1000 joinedFunding-child
    1000 Förderer Volkswagen Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
  3. 1000 joinedFunding-child
    1000 Förderer Barilla & Co |
    1000 Förderprogramm -
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer European Commission (ATHENA) |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6407117.rdf
1000 Erstellt am 2018-03-14T15:16:45.571+0100
1000 Erstellt von 266
1000 beschreibt frl:6407117
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Thu Mar 15 09:44:44 CET 2018
1000 Objekt bearb. Wed Mar 14 15:17:52 CET 2018
1000 Vgl. frl:6407117
1000 Oai Id
  1. oai:frl.publisso.de:frl:6407117 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source