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Erhardt-et-al_2014_Reference values for leptin.pdf 633,75KB
WeightNameValue
1000 Titel
  • Reference values for leptin and adiponectin in children below the age of 10 based on the IDEFICS cohort
1000 Autor/in
  1. Erhardt, Eva |
  2. Foraita, Ronja |
  3. Pigeot, Iris |
  4. Barba, Gianvincenzo |
  5. Veidebaum, Toomas |
  6. Tornaritis, Michael |
  7. Michels, Nathalie |
  8. Eiben, Gabriele |
  9. Ahrens, Wolfgang |
  10. Moreno, Luis A. |
  11. Kovács, Eva |
  12. Molnar, Dénes |
1000 Mitwirkende/r
  1. The IDEFICS consortium |
1000 Erscheinungsjahr 2014
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2014-09-15
1000 Erschienen in
1000 Quellenangabe
  • 38: S32-S38
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2014
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1038/ijo.2014.133 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • OBJECTIVE: To establish age- and sex-specific reference values for serum leptin and adiponectin in normal-weight 3.0–8.9-year old European children. SUBJECTS AND METHODS: Blood samples for hormone analysis were taken from 1338 children of the IDEFICS (Identification and prevention of Dietary- and lifestyle-induced health Effects in Children and infantS) study cohort. Only normal-weight children aged 3.0–8.9 years were included (n=539) in our analysis. Using the General Additive Model for Location Scale and Shape, age- and sex-specific percentiles were derived. The influence of under/overweight and obesity on the proposed reference curves based on normal-weight children was investigated in several sensitivity analyses using the sample without obese children (n=1015) and the whole study sample (n=1338). RESULTS: There was a negative age trend of adiponectin blood levels and a positive trend of leptin levels in boys and girls. Percentiles derived for girls were generally higher than those obtained for boys. The corresponding age-specific differences of the 97th percentile ranged from −2.2 to 4.6 μg ml−1 and from 2.2 to 4.8 ng ml−1 for adiponectin and leptin, respectively. CONCLUSIONS: According to our knowledge, these are the first reference values of leptin and adiponectin in prepubertal, normal-weight children. The presented adiponectin and leptin reference curves may allow for a more differentiated interpretation of children’s hormone levels in epidemiological and clinical studies.
1000 Sacherschließung
lokal Obesity
lokal Diagnosis
lokal Metabolic disorders
lokal Paediatrics
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
  3. Ernährungswissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/RXJoYXJkdCwgRXZh|https://frl.publisso.de/adhoc/creator/Rm9yYWl0YSwgUm9uamE=|http://orcid.org/0000-0001-7483-0726|https://frl.publisso.de/adhoc/creator/QmFyYmEsIEdpYW52aW5jZW56bw==|https://frl.publisso.de/adhoc/creator/VmVpZGViYXVtLCBUb29tYXM=|https://frl.publisso.de/adhoc/creator/VG9ybmFyaXRpcywgTWljaGFlbA==|https://frl.publisso.de/adhoc/creator/TWljaGVscywgTmF0aGFsaWU=|https://frl.publisso.de/adhoc/creator/RWliZW4sIEdhYnJpZWxl|http://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/creator/TW9yZW5vLCBMdWlzIEEu|https://frl.publisso.de/adhoc/creator/S292w6FjcywgRXZh|https://frl.publisso.de/adhoc/creator/TW9sbmFyLCBEw6luZXM=|https://frl.publisso.de/adhoc/corporateBody/VGhlIElERUZJQ1MgY29uc29ydGl1bQ==
1000 Förderer
  1. European Community |
  2. Volkswagen Foundation |
1000 Fördernummer
  1. 016181 (FOOD)
  2. -
1000 Förderprogramm
  1. Sixth Framework Programme
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Community |
    1000 Förderprogramm Sixth Framework Programme
    1000 Fördernummer 016181 (FOOD)
  2. 1000 joinedFunding-child
    1000 Förderer Volkswagen Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6407122.rdf
1000 Erstellt am 2018-03-14T15:59:06.007+0100
1000 Erstellt von 266
1000 beschreibt frl:6407122
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Tue May 29 12:47:01 CEST 2018
1000 Objekt bearb. Tue May 29 12:47:01 CEST 2018
1000 Vgl. frl:6407122
1000 Oai Id
  1. oai:frl.publisso.de:frl:6407122 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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