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WeightNameValue
1000 Titel
  • Selective modulation of interhemispheric functional connectivity by HD-tACS shapes perception
1000 Autor/in
  1. Helfrich, Randolph F. |
  2. Knepper, Hannah |
  3. Nolte, Guido |
  4. Strüber, Daniel |
  5. Rach, Stefan |
  6. Herrmann, Christoph S. |
  7. Schneider, Till R. |
  8. Engel, Andreas K. |
1000 Erscheinungsjahr 2014
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2014-12-30
1000 Erschienen in
1000 Quellenangabe
  • 12(12): e1002031
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2014
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1371/journal.pbio.1002031 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280108/ |
1000 Ergänzendes Material
  • http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002031#s6 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Oscillatory neuronal synchronization between cortical areas has been suggested to constitute a flexible mechanism to coordinate information flow in the human cerebral cortex. However, it remains unclear whether synchronized neuronal activity merely represents an epiphenomenon or whether it is causally involved in the selective gating of information. Here, we combined bilateral high-density transcranial alternating current stimulation (HD-tACS) at 40 Hz with simultaneous electroencephalographic (EEG) recordings to study immediate electrophysiological effects during the selective entrainment of oscillatory gamma-band signatures. We found that interhemispheric functional connectivity was modulated in a predictable, phase-specific way: In-phase stimulation enhanced synchronization, anti-phase stimulation impaired functional coupling. Perceptual correlates of these connectivity changes were found in an ambiguous motion task, which strongly support the functional relevance of long-range neuronal coupling. Additionally, our results revealed a decrease in oscillatory alpha power in response to the entrainment of gamma band signatures. This finding provides causal evidence for the antagonistic role of alpha and gamma oscillations in the parieto-occipital cortex and confirms that the observed gamma band modulations were physiological in nature. Our results demonstrate that synchronized cortical network activity across several spatiotemporal scales is essential for conscious perception and cognition.
1000 Sacherschließung
lokal Electric field
lokal Vision
lokal Functional electrical stimulation
lokal Perception
lokal Electroencephalography
lokal Cognitive science
lokal Sensory perception
lokal Transcranial alternating current stimulation
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/SGVsZnJpY2gsIFJhbmRvbHBoIEYu|https://frl.publisso.de/adhoc/creator/S25lcHBlciwgSGFubmFo|https://frl.publisso.de/adhoc/creator/Tm9sdGUsIEd1aWRv|https://frl.publisso.de/adhoc/creator/U3Ryw7xiZXIsIERhbmllbA==|http://orcid.org/0000-0001-5241-0253|https://frl.publisso.de/adhoc/creator/SGVycm1hbm4sIENocmlzdG9waCBTLg==|https://frl.publisso.de/adhoc/creator/U2NobmVpZGVyLCBUaWxsIFIu|https://frl.publisso.de/adhoc/creator/RW5nZWwsIEFuZHJlYXMgSy4=
1000 Förderer
  1. European Union |
  2. German Research Foundation |
  3. German National Academic Foundation |
1000 Fördernummer
  1. ERC-2010-AdG-269716
  2. SFB936/A3/Z1; RA2357/1-1; SFB/TRR 31; SPP1665 EN 533/13-1; SPP1665 HE 3353/8-1
  3. -
1000 Förderprogramm
  1. -
  2. -
  3. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Union |
    1000 Förderprogramm -
    1000 Fördernummer ERC-2010-AdG-269716
  2. 1000 joinedFunding-child
    1000 Förderer German Research Foundation |
    1000 Förderprogramm -
    1000 Fördernummer SFB936/A3/Z1; RA2357/1-1; SFB/TRR 31; SPP1665 EN 533/13-1; SPP1665 HE 3353/8-1
  3. 1000 joinedFunding-child
    1000 Förderer German National Academic Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6407127.rdf
1000 Erstellt am 2018-03-14T16:31:56.470+0100
1000 Erstellt von 266
1000 beschreibt frl:6407127
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Thu Mar 15 10:09:55 CET 2018
1000 Objekt bearb. Thu Mar 15 10:09:20 CET 2018
1000 Vgl. frl:6407127
1000 Oai Id
  1. oai:frl.publisso.de:frl:6407127 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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