Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

  1. Wheeler, Eleanor
  2. Leong, Aaron
  3. Liu, Ching-Ti ORCID logo
  4. Hivert, Marie-France ORCID logo
  5. Strawbridge, Rona ORCID logo
  6. Podmore, Clara ORCID logo
  7. Li, Man ORCID logo
  8. Yao, Jie
  9. Sim, Xueling ORCID logo
  10. Hong, Jaeyoung
  11. Chu, Audrey Y.
  12. Zhang, Weihua
  13. Wang, Xu
  14. Chen, Peng ORCID logo
  15. Maruthur, Nisa M.
  16. Porneala, Bianca C.
  17. Sharp, Stephen ORCID logo
  18. Jia, Yucheng
  19. Kabagambe, Edmond K.
  20. Chang, Li-Ching
  21. Chen, Wei-Min
  22. Elks, Cathy E.
  23. Evans, Daniel ORCID logo
  24. Fan, Qiao
  25. Giulianini, Franco
  26. Go, Min Jin
  27. Hottenga, Jouke-Jan
  28. Hu, Yao
  29. Jackson, Anne U.
  30. Kanoni, Stavroula
  31. Kim, Young Jin ORCID logo
  32. Kleber, Marcus E.
  33. Ladenvall, Claes ORCID logo
  34. Lecoeur, Cecile ORCID logo
  35. Lim, Sing Hui ORCID logo
  36. Lu, Yingchang
  37. Mahajan, Anubha
  38. Marzi, Carola
  39. Nalls, Mike A.
  40. Navarro, Pau ORCID logo
  41. Nolte, Ilja M.
  42. Rose, Lynda M.
  43. Rybin, Denis V.
  44. sanna, serena ORCID logo
  45. Shi, Yuan
  46. Stram, Daniel O.
  47. Takeuchi, Fumihiko ORCID logo
  48. Tan, Shu Pei
  49. van der Most, Peter ORCID logo
  50. van Vliet-Ostaptchouk, Jana ORCID logo
  51. Wong, Andrew ORCID logo
  52. Yengo, Loic ORCID logo
  53. Zhao, Wanting
  54. Goel, Anuj
  55. Martinez Larrad, Maria Teresa
  56. Radke, Dörte
  57. Salo, Perttu
  58. Tanaka, Toshiko ORCID logo
  59. van Iperen, Erik P. A.
  60. Abecasis, Goncalo
  61. Afaq, Saima
  62. Ziad Alizadeh, Behrooz ORCID logo
  63. Bertoni, Alain G.
  64. Bonnefond, Amelie
  65. Böttcher, Yvonne
  66. Bottinger, Erwin ORCID logo
  67. Campbell, Harry ORCID logo
  68. Carlson, Olga ORCID logo
  69. Chen, Chien-Hsiun
  70. Cho, Yoon Shin
  71. Garvey, W. Timothy
  72. Gieger, Christian
  73. Goodarzi, Mark O.
  74. Grallert, Harald
  75. Hamsten, Anders
  76. Hartman, Catharina A.
  77. Herder, Christian ORCID logo
  78. Hsiung, Chao Agnes
  79. huang, jie ORCID logo
  80. Igase, Michiya
  81. Isono, Masato
  82. Katsuya, Tomohiro ORCID logo
  83. Khor, Chiea-Chuen
  84. Kiess, Wieland
  85. Kohara, Katsuhiko
  86. Kovacs, Peter ORCID logo
  87. Lee, Juyoung
  88. Lee, Wen-Jane ORCID logo
  89. Lehne, Benjamin
  90. Li, Huaixing
  91. Liu, Jianjun
  92. Lobbens, Stephane
  93. Luan, Jian'an
  94. Lyssenko, Valeriya
  95. Meitinger, Thomas
  96. Miki, Tetsuro
  97. Miljkovic, Iva ORCID logo
  98. Moon, Sanghoon
  99. Mulas, Antonella
  100. Müller, Gabriele ORCID logo
  101. Müller-Nurasyid, Martina
  102. Nagaraja, Ramaiah
  103. Nauck, Matthias
  104. Pankow, James S.
  105. Polasek, Ozren
  106. Prokopenko, Inga
  107. Ramos, Paula ORCID logo
  108. Rasmussen-Torvik, Laura
  109. Rathmann, Wolfgang
  110. Rich, Stephen S.
  111. Robertson, Neil R.
  112. Roden, Michael
  113. Roussel, Ronan
  114. Rudan, Igor
  115. Scott, Robert A.
  116. Scott, William R.
  117. Sennblad, Bengt
  118. Siscovick, David S.
  119. Strauch, Konstantin
  120. Sun, Liang
  121. Swertz, Morris ORCID logo
  122. Tajuddin, Salman M. ORCID logo
  123. Taylor, Kent D.
  124. Teo, Yik-Ying
  125. Tham, Yih Chung
  126. Tönjes, Anke
  127. Wareham, Nicholas ORCID logo
  128. Willemsen, Gonneke
  129. Wilsgaard, Tom
  130. Hingorani, Aroon ORCID logo
  131. EPIC-CVD Consortium
  132. EPIC-InterAct Consortium
  133. Lifelines Cohort Study
  134. Egan, Josephine
  135. Ferrucci, Luigi ORCID logo
  136. Hovingh, G. Kees
  137. Jula, Antti
  138. Kivimaki, Mika ORCID logo
  139. Kumari, Meena
  140. Njølstad, Inger
  141. Palmer, Colin ORCID logo
  142. Ríos, Manuel Serrano
  143. Stumvoll, Michael
  144. Watkins, Hugh
  145. Aung, Tin
  146. Blüher, Matthias
  147. Boehnke, Michael
  148. Boomsma, Dorret ORCID logo
  149. Bornstein, Stefan R.
  150. Chambers, John C.
  151. Chasman, Daniel I.
  152. Chen, Yii-Der Ida
  153. Chen, Yduan-Tsong
  154. Cheng, Ching-Yu
  155. CUCCA, Francesco ORCID logo
  156. de Geus, Eco ORCID logo
  157. Deloukas, Panos
  158. Evans, Michele K.
  159. Fornage, Myriam
  160. Friedlander, Yechiel ORCID logo
  161. Froguel, Philippe
  162. Groop, Leif
  163. Gross, Myron D.
  164. Harris, Tamara B.
  165. Hayward, Caroline
  166. Heng, Chew Kiat ORCID logo
  167. Ingelsson, Erik
  168. Kato, Norihiro
  169. Kim, Bong-Jo
  170. Koh, Woon-Puay
  171. Kooner, Jaspal S.
  172. Körner, Antje
  173. Kuh, Diana
  174. Kuusisto, Johanna
  175. Laakso, Markku
  176. Lin, Xu
  177. Liu, Yongmei
  178. Loos, Ruth J. F.
  179. Magnusson, Patrik ORCID logo
  180. März, Winfried
  181. McCarthy, Mark ORCID logo
  182. , Albertine ORCID logo
  183. Ong, Ken ORCID logo
  184. Pedersen, Nancy L.
  185. Pereira, Mark ORCID logo
  186. Peters, Annette ORCID logo
  187. Ridker, Paul M.
  188. Sabanayagam, Charumathi ORCID logo
  189. Sale, Michele ORCID logo
  190. Saleheen, Danish
  191. Saltevo, Juha
  192. Schwarz, Peter EH.
  193. Sheu, Wayne H. H.
  194. Snieder, Harold
  195. Spector, Timothy D.
  196. Tabara, Yasuharu
  197. Tuomilehto, Jaakko
  198. van Dam, Rob ORCID logo
  199. Wilson, James G.
  200. Wilson, James F ORCID logo
  201. Wolffenbuttel, Bruce H. R.
  202. Wong, Tien Y ORCID logo
  203. Wu, Jer-Yuarn
  204. Yuan, Jian-Min ORCID logo
  205. Zonderman, Alan B.
  206. Soranzo, Nicole
  207. Guo, Xiuqing
  208. Roberts, David J.
  209. Florez, Jose C.
  210. Sladek, Robert ORCID logo
  211. Dupuis, Josee ORCID logo
  212. Morris, Andrew ORCID logo
  213. Tai, E-Shyong
  214. Selvin, Elizabeth
  215. Rotter, Jerome I.
  216. Langenberg, Claudia ORCID logo
  217. Barroso, Ines ORCID logo
  218. Meigs, James B.

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WeightNameValue
1000 Titel
  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
1000 Autor/in
  1. Wheeler, Eleanor |
  2. Leong, Aaron |
  3. Liu, Ching-Ti |
  4. Hivert, Marie-France |
  5. Strawbridge, Rona |
  6. Podmore, Clara |
  7. Li, Man |
  8. Yao, Jie |
  9. Sim, Xueling |
  10. Hong, Jaeyoung |
  11. Chu, Audrey Y. |
  12. Zhang, Weihua |
  13. Wang, Xu |
  14. Chen, Peng |
  15. Maruthur, Nisa M. |
  16. Porneala, Bianca C. |
  17. Sharp, Stephen |
  18. Jia, Yucheng |
  19. Kabagambe, Edmond K. |
  20. Chang, Li-Ching |
  21. Chen, Wei-Min |
  22. Elks, Cathy E. |
  23. Evans, Daniel |
  24. Fan, Qiao |
  25. Giulianini, Franco |
  26. Go, Min Jin |
  27. Hottenga, Jouke-Jan |
  28. Hu, Yao |
  29. Jackson, Anne U. |
  30. Kanoni, Stavroula |
  31. Kim, Young Jin |
  32. Kleber, Marcus E. |
  33. Ladenvall, Claes |
  34. Lecoeur, Cecile |
  35. Lim, Sing Hui |
  36. Lu, Yingchang |
  37. Mahajan, Anubha |
  38. Marzi, Carola |
  39. Nalls, Mike A. |
  40. Navarro, Pau |
  41. Nolte, Ilja M. |
  42. Rose, Lynda M. |
  43. Rybin, Denis V. |
  44. sanna, serena |
  45. Shi, Yuan |
  46. Stram, Daniel O. |
  47. Takeuchi, Fumihiko |
  48. Tan, Shu Pei |
  49. van der Most, Peter |
  50. van Vliet-Ostaptchouk, Jana |
  51. Wong, Andrew |
  52. Yengo, Loic |
  53. Zhao, Wanting |
  54. Goel, Anuj |
  55. Martinez Larrad, Maria Teresa |
  56. Radke, Dörte |
  57. Salo, Perttu |
  58. Tanaka, Toshiko |
  59. van Iperen, Erik P. A. |
  60. Abecasis, Goncalo |
  61. Afaq, Saima |
  62. Ziad Alizadeh, Behrooz |
  63. Bertoni, Alain G. |
  64. Bonnefond, Amelie |
  65. Böttcher, Yvonne |
  66. Bottinger, Erwin |
  67. Campbell, Harry |
  68. Carlson, Olga |
  69. Chen, Chien-Hsiun |
  70. Cho, Yoon Shin |
  71. Garvey, W. Timothy |
  72. Gieger, Christian |
  73. Goodarzi, Mark O. |
  74. Grallert, Harald |
  75. Hamsten, Anders |
  76. Hartman, Catharina A. |
  77. Herder, Christian |
  78. Hsiung, Chao Agnes |
  79. huang, jie |
  80. Igase, Michiya |
  81. Isono, Masato |
  82. Katsuya, Tomohiro |
  83. Khor, Chiea-Chuen |
  84. Kiess, Wieland |
  85. Kohara, Katsuhiko |
  86. Kovacs, Peter |
  87. Lee, Juyoung |
  88. Lee, Wen-Jane |
  89. Lehne, Benjamin |
  90. Li, Huaixing |
  91. Liu, Jianjun |
  92. Lobbens, Stephane |
  93. Luan, Jian'an |
  94. Lyssenko, Valeriya |
  95. Meitinger, Thomas |
  96. Miki, Tetsuro |
  97. Miljkovic, Iva |
  98. Moon, Sanghoon |
  99. Mulas, Antonella |
  100. Müller, Gabriele |
  101. Müller-Nurasyid, Martina |
  102. Nagaraja, Ramaiah |
  103. Nauck, Matthias |
  104. Pankow, James S. |
  105. Polasek, Ozren |
  106. Prokopenko, Inga |
  107. Ramos, Paula |
  108. Rasmussen-Torvik, Laura |
  109. Rathmann, Wolfgang |
  110. Rich, Stephen S. |
  111. Robertson, Neil R. |
  112. Roden, Michael |
  113. Roussel, Ronan |
  114. Rudan, Igor |
  115. Scott, Robert A. |
  116. Scott, William R. |
  117. Sennblad, Bengt |
  118. Siscovick, David S. |
  119. Strauch, Konstantin |
  120. Sun, Liang |
  121. Swertz, Morris |
  122. Tajuddin, Salman M. |
  123. Taylor, Kent D. |
  124. Teo, Yik-Ying |
  125. Tham, Yih Chung |
  126. Tönjes, Anke |
  127. Wareham, Nicholas |
  128. Willemsen, Gonneke |
  129. Wilsgaard, Tom |
  130. Hingorani, Aroon |
  131. EPIC-CVD Consortium |
  132. EPIC-InterAct Consortium |
  133. Lifelines Cohort Study |
  134. Egan, Josephine |
  135. Ferrucci, Luigi |
  136. Hovingh, G. Kees |
  137. Jula, Antti |
  138. Kivimaki, Mika |
  139. Kumari, Meena |
  140. Njølstad, Inger |
  141. Palmer, Colin |
  142. Ríos, Manuel Serrano |
  143. Stumvoll, Michael |
  144. Watkins, Hugh |
  145. Aung, Tin |
  146. Blüher, Matthias |
  147. Boehnke, Michael |
  148. Boomsma, Dorret |
  149. Bornstein, Stefan R. |
  150. Chambers, John C. |
  151. Chasman, Daniel I. |
  152. Chen, Yii-Der Ida |
  153. Chen, Yduan-Tsong |
  154. Cheng, Ching-Yu |
  155. CUCCA, Francesco |
  156. de Geus, Eco |
  157. Deloukas, Panos |
  158. Evans, Michele K. |
  159. Fornage, Myriam |
  160. Friedlander, Yechiel |
  161. Froguel, Philippe |
  162. Groop, Leif |
  163. Gross, Myron D. |
  164. Harris, Tamara B. |
  165. Hayward, Caroline |
  166. Heng, Chew Kiat |
  167. Ingelsson, Erik |
  168. Kato, Norihiro |
  169. Kim, Bong-Jo |
  170. Koh, Woon-Puay |
  171. Kooner, Jaspal S. |
  172. Körner, Antje |
  173. Kuh, Diana |
  174. Kuusisto, Johanna |
  175. Laakso, Markku |
  176. Lin, Xu |
  177. Liu, Yongmei |
  178. Loos, Ruth J. F. |
  179. Magnusson, Patrik |
  180. März, Winfried |
  181. McCarthy, Mark |
  182. , Albertine |
  183. Ong, Ken |
  184. Pedersen, Nancy L. |
  185. Pereira, Mark |
  186. Peters, Annette |
  187. Ridker, Paul M. |
  188. Sabanayagam, Charumathi |
  189. Sale, Michele |
  190. Saleheen, Danish |
  191. Saltevo, Juha |
  192. Schwarz, Peter EH. |
  193. Sheu, Wayne H. H. |
  194. Snieder, Harold |
  195. Spector, Timothy D. |
  196. Tabara, Yasuharu |
  197. Tuomilehto, Jaakko |
  198. van Dam, Rob |
  199. Wilson, James G. |
  200. Wilson, James F |
  201. Wolffenbuttel, Bruce H. R. |
  202. Wong, Tien Y |
  203. Wu, Jer-Yuarn |
  204. Yuan, Jian-Min |
  205. Zonderman, Alan B. |
  206. Soranzo, Nicole |
  207. Guo, Xiuqing |
  208. Roberts, David J. |
  209. Florez, Jose C. |
  210. Sladek, Robert |
  211. Dupuis, Josee |
  212. Morris, Andrew |
  213. Tai, E-Shyong |
  214. Selvin, Elizabeth |
  215. Rotter, Jerome I. |
  216. Langenberg, Claudia |
  217. Barroso, Ines |
  218. Meigs, James B. |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-09-12
1000 Erschienen in
1000 Quellenangabe
  • 14(9):e1002383
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pmed.1002383 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595282/ |
1000 Ergänzendes Material
  • http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002383#sec027 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or glycemic (associated with other glucose-related traits). In this study, we tested the hypotheses that, in a very large scale GWAS, we would identify more genetic variants associated with HbA1c and that HbA1c variants implicated in erythrocytic biology would affect the diagnostic accuracy of HbA1c. We therefore expanded the number of HbA1c-associated loci and tested the effect of genetic risk-scores comprised of erythrocytic or glycemic variants on incident diabetes prediction and on prevalent diabetes screening performance. Throughout this multiancestry study, we kept a focus on interancestry differences in HbA1c genetics performance that might influence race-ancestry differences in health outcomes.METHODS AND FINDING: Using genome-wide association meta-analyses in up to 159,940 individuals from 82 cohorts of European, African, East Asian, and South Asian ancestry, we identified 60 common genetic variants associated with HbA1c. We classified variants as implicated in glycemic, erythrocytic, or unclassified biology and tested whether additive genetic scores of erythrocytic variants (GS-E) or glycemic variants (GS-G) were associated with higher T2D incidence in multiethnic longitudinal cohorts (N = 33,241). Nineteen glycemic and 22 erythrocytic variants were associated with HbA1c at genome-wide significance. GS-G was associated with higher T2D risk (incidence OR = 1.05, 95% CI 1.04–1.06, per HbA1c-raising allele, p = 3 × 10−29); whereas GS-E was not (OR = 1.00, 95% CI 0.99–1.01, p = 0.60). In Europeans and Asians, erythrocytic variants in aggregate had only modest effects on the diagnostic accuracy of HbA1c. Yet, in African Americans, the X-linked G6PD G202A variant (T-allele frequency 11%) was associated with an absolute decrease in HbA1c of 0.81%-units (95% CI 0.66–0.96) per allele in hemizygous men, and 0.68%-units (95% CI 0.38–0.97) in homozygous women. The G6PD variant may cause approximately 2% (N = 0.65 million, 95% CI 0.55–0.74) of African American adults with T2D to remain undiagnosed when screened with HbA1c. Limitations include the smaller sample sizes for non-European ancestries and the inability to classify approximately one-third of the variants. Further studies in large multiethnic cohorts with HbA1c, glycemic, and erythrocytic traits are required to better determine the biological action of the unclassified variants. CONCLUSIONS: As G6PD deficiency can be clinically silent until illness strikes, we recommend investigation of the possible benefits of screening for the G6PD genotype along with using HbA1c to diagnose T2D in populations of African ancestry or groups where G6PD deficiency is common. Screening with direct glucose measurements, or genetically-informed HbA1c diagnostic thresholds in people with G6PD deficiency, may be required to avoid missed or delayed diagnoses.
1000 Sacherschließung
lokal Type 2 diabetes
lokal African American people
lokal Genome-wide association studies
lokal Diabetes diagnosis and management
lokal Diabetes mellitus
lokal HbA1c
lokal Human genetics
lokal Meta-analysis
1000 Fachgruppe
  1. Medizin |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/V2hlZWxlciwgRWxlYW5vcg==|https://frl.publisso.de/adhoc/creator/TGVvbmcsIEFhcm9u|http://orcid.org/0000-0002-0703-0742|http://orcid.org/0000-0001-7752-2585|http://orcid.org/0000-0001-8506-3585|http://orcid.org/0000-0002-2452-8067|http://orcid.org/0000-0002-3839-0281|https://frl.publisso.de/adhoc/creator/WWFvLCBKaWU=|http://orcid.org/0000-0002-1233-7642|https://frl.publisso.de/adhoc/creator/SG9uZywgSmFleW91bmcg|https://frl.publisso.de/adhoc/creator/Q2h1LCBBdWRyZXkgWS4g|https://frl.publisso.de/adhoc/creator/WmhhbmcsIFdlaWh1YSA=|https://frl.publisso.de/adhoc/creator/V2FuZywgWHUg|http://orcid.org/0000-0002-1422-4641|https://frl.publisso.de/adhoc/creator/TWFydXRodXIsIE5pc2EgTS4g|https://frl.publisso.de/adhoc/creator/UG9ybmVhbGEsIEJpYW5jYSBDLiA=|http://orcid.org/0000-0003-2375-1440|https://frl.publisso.de/adhoc/creator/SmlhLCBZdWNoZW5nIA==|https://frl.publisso.de/adhoc/creator/S2FiYWdhbWJlLCBFZG1vbmQgSy4g|https://frl.publisso.de/adhoc/creator/Q2hhbmcsIExpLUNoaW5nIA==|https://frl.publisso.de/adhoc/creator/Q2hlbiwgV2VpLU1pbiA=|https://frl.publisso.de/adhoc/creator/RWxrcywgQ2F0aHkgRS4g|http://orcid.org/0000-0003-4185-7687|https://frl.publisso.de/adhoc/creator/RmFuLCBRaWFvIA==|https://frl.publisso.de/adhoc/creator/R2l1bGlhbmluaSwgRnJhbmNvIA==|https://frl.publisso.de/adhoc/creator/R28sIE1pbiBKaW4g|https://frl.publisso.de/adhoc/creator/SG90dGVuZ2EsIEpvdWtlLUphbiA=|https://frl.publisso.de/adhoc/creator/SHUsIFlhbyA=|https://frl.publisso.de/adhoc/creator/SmFja3NvbiwgQW5uZSBVLiA=|https://frl.publisso.de/adhoc/creator/S2Fub25pLCBTdGF2cm91bGEg|http://orcid.org/0000-0002-4132-4437|https://frl.publisso.de/adhoc/creator/S2xlYmVyLCBNYXJjdXMgRS4g|http://orcid.org/0000-0002-7501-6598|http://orcid.org/0000-0003-0075-6417|http://orcid.org/0000-0002-3793-9658|https://frl.publisso.de/adhoc/creator/THUsIFlpbmdjaGFuZyA=|https://frl.publisso.de/adhoc/creator/TWFoYWphbiwgQW51YmhhIA==|https://frl.publisso.de/adhoc/creator/TWFyemksIENhcm9sYSA=|https://frl.publisso.de/adhoc/creator/TmFsbHMsIE1pa2UgQS4g|http://orcid.org/0000-0001-5576-8584|https://frl.publisso.de/adhoc/creator/Tm9sdGUsIElsamEgTS4g|https://frl.publisso.de/adhoc/creator/Um9zZSwgTHluZGEgTS4g|https://frl.publisso.de/adhoc/creator/UnliaW4sIERlbmlzIFYuIA==|http://orcid.org/0000-0002-3768-1749|https://frl.publisso.de/adhoc/creator/U2hpLCBZdWFuIA==|https://frl.publisso.de/adhoc/creator/U3RyYW0sIERhbmllbCBPLiA=|http://orcid.org/0000-0003-3185-5661|https://frl.publisso.de/adhoc/creator/VGFuLCBTaHUgUGVpIA==|http://orcid.org/0000-0001-8450-3518|http://orcid.org/0000-0002-7943-3153|http://orcid.org/0000-0003-2079-4779|http://orcid.org/0000-0002-4272-9305|https://frl.publisso.de/adhoc/creator/WmhhbywgV2FudGluZyA=|https://frl.publisso.de/adhoc/creator/R29lbCwgQW51aiA=|https://frl.publisso.de/adhoc/creator/TWFydGluZXogTGFycmFkLCBNYXJpYSBUZXJlc2Eg|https://frl.publisso.de/adhoc/creator/UmFka2UsIETDtnJ0ZSA=|https://frl.publisso.de/adhoc/creator/U2FsbywgUGVydHR1IA==|http://orcid.org/0000-0002-4161-3829|https://frl.publisso.de/adhoc/creator/dmFuIElwZXJlbiwgRXJpayBQLiBBLiA=|https://frl.publisso.de/adhoc/creator/QWJlY2FzaXMsIEdvbmNhbG8g|https://frl.publisso.de/adhoc/creator/QWZhcSwgU2FpbWEg|http://orcid.org/0000-0002-1415-8007|https://frl.publisso.de/adhoc/creator/QmVydG9uaSwgQWxhaW4gRy4g|https://frl.publisso.de/adhoc/creator/Qm9ubmVmb25kLCBBbWVsaWUg|https://frl.publisso.de/adhoc/creator/QsO2dHRjaGVyLCBZdm9ubmUg|http://orcid.org/0000-0001-6868-6676|http://orcid.org/0000-0002-6169-6262|http://orcid.org/0000-0003-4099-7178|https://frl.publisso.de/adhoc/creator/Q2hlbiwgQ2hpZW4tSHNpdW4g|https://frl.publisso.de/adhoc/creator/Q2hvLCBZb29uIFNoaW4g|https://frl.publisso.de/adhoc/creator/R2FydmV5LCBXLiBUaW1vdGh5IA==|https://frl.publisso.de/adhoc/creator/R2llZ2VyLCBDaHJpc3RpYW4g|https://frl.publisso.de/adhoc/creator/R29vZGFyemksIE1hcmsgTy4g|https://frl.publisso.de/adhoc/creator/R3JhbGxlcnQsIEhhcmFsZCA=|https://frl.publisso.de/adhoc/creator/SGFtc3RlbiwgQW5kZXJzIA==|https://frl.publisso.de/adhoc/creator/SGFydG1hbiwgQ2F0aGFyaW5hIEEu|http://orcid.org/0000-0002-2050-093X|https://frl.publisso.de/adhoc/creator/SHNpdW5nLCBDaGFvIEFnbmVzIA==|http://orcid.org/0000-0002-9441-4698|https://frl.publisso.de/adhoc/creator/SWdhc2UsIE1pY2hpeWEg|https://frl.publisso.de/adhoc/creator/SXNvbm8sIE1hc2F0byA=|http://orcid.org/0000-0002-8892-8828|https://frl.publisso.de/adhoc/creator/S2hvciwgQ2hpZWEtQ2h1ZW4g|https://frl.publisso.de/adhoc/creator/S2llc3MsIFdpZWxhbmQ=|https://frl.publisso.de/adhoc/creator/S29oYXJhLCBLYXRzdWhpa28g|http://orcid.org/0000-0002-0290-5423|https://frl.publisso.de/adhoc/creator/TGVlLCBKdXlvdW5nIA==|http://orcid.org/0000-0002-4390-8129|https://frl.publisso.de/adhoc/creator/TGVobmUsIEJlbmphbWluIA==|https://frl.publisso.de/adhoc/creator/TGksIEh1YWl4aW5nIA==|https://frl.publisso.de/adhoc/creator/TGl1LCBKaWFuanVuIA==|https://frl.publisso.de/adhoc/creator/TG9iYmVucywgU3RlcGhhbmUg|https://frl.publisso.de/adhoc/creator/THVhbiwgSmlhbidhbiA=|https://frl.publisso.de/adhoc/creator/THlzc2Vua28sIFZhbGVyaXlhIA==|https://frl.publisso.de/adhoc/creator/TWVpdGluZ2VyLCBUaG9tYXMg|https://frl.publisso.de/adhoc/creator/TWlraSwgVGV0c3Vybw==|http://orcid.org/0000-0002-3155-9777|https://frl.publisso.de/adhoc/creator/TW9vbiwgU2FuZ2hvb24g|https://frl.publisso.de/adhoc/creator/TXVsYXMsIEFudG9uZWxsYSA=|http://orcid.org/0000-0002-1591-0539|https://frl.publisso.de/adhoc/creator/TcO8bGxlci1OdXJhc3lpZCwgTWFydGluYSA=|https://frl.publisso.de/adhoc/creator/TmFnYXJhamEsIFJhbWFpYWg=|https://frl.publisso.de/adhoc/creator/TmF1Y2ssIE1hdHRoaWFzIA==|https://frl.publisso.de/adhoc/creator/UGFua293LCBKYW1lcyBTLg==|https://frl.publisso.de/adhoc/creator/UG9sYXNlaywgT3pyZW4=|https://frl.publisso.de/adhoc/creator/UHJva29wZW5rbywgSW5nYQ==|http://orcid.org/0000-0002-9433-6634|https://frl.publisso.de/adhoc/creator/UmFzbXVzc2VuLVRvcnZpaywgTGF1cmE=|https://frl.publisso.de/adhoc/creator/UmF0aG1hbm4sIFdvbGZnYW5nIA==|https://frl.publisso.de/adhoc/creator/UmljaCwgU3RlcGhlbiBTLg==|https://frl.publisso.de/adhoc/creator/Um9iZXJ0c29uLCBOZWlsIFIu|http://d-nb.info/gnd/130812773|https://frl.publisso.de/adhoc/creator/Um91c3NlbCwgUm9uYW4=|https://frl.publisso.de/adhoc/creator/UnVkYW4sIElnb3I=|https://frl.publisso.de/adhoc/creator/U2NvdHQsIFJvYmVydCBBLg==|https://frl.publisso.de/adhoc/creator/U2NvdHQsIFdpbGxpYW0gUi4=|https://frl.publisso.de/adhoc/creator/U2VubmJsYWQsIEJlbmd0|https://frl.publisso.de/adhoc/creator/U2lzY292aWNrLCBEYXZpZCBTLg==|https://frl.publisso.de/adhoc/creator/U3RyYXVjaCwgS29uc3RhbnRpbg==|https://frl.publisso.de/adhoc/creator/U3VuLCBMaWFuZw==|http://orcid.org/0000-0002-0979-3401|http://orcid.org/0000-0002-7919-8528|https://frl.publisso.de/adhoc/creator/VGF5bG9yLCBLZW50IEQu|https://frl.publisso.de/adhoc/creator/VGVvLCBZaWstWWluZw==|https://frl.publisso.de/adhoc/creator/VGhhbSwgWWloIENodW5n|https://frl.publisso.de/adhoc/creator/VMO2bmplcywgQW5rZQ==|http://orcid.org/0000-0003-1422-2993|https://frl.publisso.de/adhoc/creator/V2lsbGVtc2VuLCBHb25uZWtl|https://frl.publisso.de/adhoc/creator/V2lsc2dhYXJkLCBUb20=|http://orcid.org/0000-0001-8365-0081|https://frl.publisso.de/adhoc/creator/RVBJQy1DVkQgQ29uc29ydGl1bSA=|https://frl.publisso.de/adhoc/creator/RVBJQy1JbnRlckFjdCBDb25zb3J0aXVtIA==|https://frl.publisso.de/adhoc/creator/TGlmZWxpbmVzIENvaG9ydCBTdHVkeSA=|https://frl.publisso.de/adhoc/creator/RWdhbiwgSm9zZXBoaW5l|http://orcid.org/0000-0002-6273-1613|https://frl.publisso.de/adhoc/creator/SG92aW5naCwgRy4gS2Vlcw==|https://frl.publisso.de/adhoc/creator/SnVsYSwgQW50dGk=|http://orcid.org/0000-0002-4699-5627|https://frl.publisso.de/adhoc/creator/S3VtYXJpLCBNZWVuYQ==|https://frl.publisso.de/adhoc/creator/TmrDuGxzdGFkLCBJbmdlcg==|http://orcid.org/0000-0002-6415-6560|https://frl.publisso.de/adhoc/creator/UsOtb3MsIE1hbnVlbCBTZXJyYW5v|https://frl.publisso.de/adhoc/creator/U3R1bXZvbGwsIE1pY2hhZWw=|https://frl.publisso.de/adhoc/creator/V2F0a2lucywgSHVnaCA=|https://frl.publisso.de/adhoc/creator/QXVuZywgVGlu|https://frl.publisso.de/adhoc/creator/QmzDvGhlciwgTWF0dGhpYXM=|https://frl.publisso.de/adhoc/creator/Qm9laG5rZSwgTWljaGFlbA==|http://orcid.org/0000-0002-7099-7972|https://frl.publisso.de/adhoc/creator/Qm9ybnN0ZWluLCBTdGVmYW4gUi4g|https://frl.publisso.de/adhoc/creator/Q2hhbWJlcnMsIEpvaG4gQy4=|https://frl.publisso.de/adhoc/creator/Q2hhc21hbiwgRGFuaWVsIEku|https://frl.publisso.de/adhoc/creator/Q2hlbiwgWWlpLURlciBJZGE=|https://frl.publisso.de/adhoc/creator/Q2hlbiwgWWR1YW4tVHNvbmc=|https://frl.publisso.de/adhoc/creator/Q2hlbmcsIENoaW5nLVl1|http://orcid.org/0000-0002-7414-1995|http://orcid.org/0000-0001-6022-2666|https://frl.publisso.de/adhoc/creator/RGVsb3VrYXMsIFBhbm9z|https://frl.publisso.de/adhoc/creator/RXZhbnMsIE1pY2hlbGUgSy4=|https://frl.publisso.de/adhoc/creator/Rm9ybmFnZSwgTXlyaWFtIA==|http://orcid.org/0000-0001-6783-3531|https://frl.publisso.de/adhoc/creator/RnJvZ3VlbCwgUGhpbGlwcGU=|https://frl.publisso.de/adhoc/creator/R3Jvb3AsIExlaWYg|https://frl.publisso.de/adhoc/creator/R3Jvc3MsIE15cm9uIEQu|https://frl.publisso.de/adhoc/creator/SGFycmlzLCBUYW1hcmEgQi4=|https://frl.publisso.de/adhoc/creator/SGF5d2FyZCwgQ2Fyb2xpbmU=|http://orcid.org/0000-0002-7309-9473|https://frl.publisso.de/adhoc/creator/SW5nZWxzc29uLCBFcmlr|https://frl.publisso.de/adhoc/creator/S2F0bywgTm9yaWhpcm8=|https://frl.publisso.de/adhoc/creator/S2ltLCBCb25nLUpv|https://frl.publisso.de/adhoc/creator/S29oLCBXb29uLVB1YXk=|https://frl.publisso.de/adhoc/creator/S29vbmVyLCBKYXNwYWwgUy4=|https://frl.publisso.de/adhoc/creator/S8O2cm5lciwgQW50amU=|https://frl.publisso.de/adhoc/creator/S3VoLCBEaWFuYQ==|https://frl.publisso.de/adhoc/creator/S3V1c2lzdG8sIEpvaGFubmE=|https://frl.publisso.de/adhoc/creator/TGFha3NvLCBNYXJra3U=|https://frl.publisso.de/adhoc/creator/TGluLCBYdQ==|https://frl.publisso.de/adhoc/creator/TGl1LCBZb25nbWVp|https://frl.publisso.de/adhoc/creator/TG9vcywgUnV0aCBKLiBGLg==|http://orcid.org/0000-0002-7315-7899|https://frl.publisso.de/adhoc/creator/TcOkcnosIFdpbmZyaWVk|http://orcid.org/0000-0002-4393-0510|http://orcid.org/0000-0003-3925-3913|http://orcid.org/0000-0003-4689-7530|h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1000 Label
1000 Förderer
  1. Ministry of Education, Culture, Sports, Science, and Technology, Japan
  2. Japan Science and Technology Agency
  3. Japan Atherosclerosis Prevention Fund
  4. Takeda Medical Research Foundation
  5. Japanese National Cardiovascular Research
  6. Dutch Science Organisation
  7. CardioVascular Research Initiative
  8. European Union
  9. Wellcome Trust
  10. National Heart, Lung, and Blood Institute (NHLBI)
  11. National Human Genome Research Institute
  12. National Institutes of Health (NIH)
  13. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  14. National Institute of Allergy and Infectious Diseases (NIAID)
  15. National Human Genome Research Institute (NHGRI)
  16. National Institute of Child Health and Human Development (NICHD)
  17. Juvenile Diabetes Research Foundation International (JDRF)
  18. National Institute for Health Research Cambridge Biomedical Research Centre
  19. Medical Research Council UK
  20. Magnus Bergvall foundation
  21. Foundation for old servants
  22. Andrea and Charles Bronfman Philanthropies
  23. NIH, National Institute on Aging
  24. National Institute of Biomedical Innovation Organization (NIBIO)
  25. National Center for Global Health and Medicine (NCGM)
  26. University of Alabama at Birmingham
  27. Northwestern University
  28. University of Minnesota
  29. Kaiser Foundation Research Institute
  30. Johns Hopkins University School of Medicine
  31. Croatian Ministry of Science, Education and sports
  32. Croatian Science Foundation
  33. CNAMTS
  34. Lilly
  35. Novartis Pharma
  36. Sanofi-Aventis
  37. INSERM (Réseaux en Santé Publique, Interactions entre les déterminants de la santé)
  38. Cohortes Santé TGIR
  39. Association Diabète Risque Vasculaire
  40. Fédération Française de Cardiologie
  41. LA Fondation de France
  42. ALFEDIAM
  43. Société francophone du diabète
  44. ONIVINS
  45. Abbott
  46. Ardix Medical
  47. Bayer Diagnostics
  48. Becton Dickinson
  49. Cardionics
  50. Merck Santé
  51. Novo Nordisk
  52. Pierre Fabre
  53. Roche
  54. Topcon
  55. NHS Blood and Transplant (UK)
  56. NIHR Biomedical Research Centre at Oxford
  57. Commission of the European Communities, Directorate C - Public Health and Risk Assessment, Health & Consumer Protection
  58. Dresden University of Technology
  59. Academy of Finland
  60. Kuopio University Hospital from Ministry of Health and Social Affairs
  61. Finnish Funding Agency for Technology and Innovation
  62. Nordic Centre of Excellence
  63. Finnish Diabetes Research Foundation
  64. Yrjö Jahnsson Foundation
  65. Sigrid Juselius Foundation
  66. TEKES
  67. Affymetrix, Inc for genotyping services
  68. Massachusetts General Hospital
  69. Canadian Diabetes Association
  70. American Diabetes Association
  71. hospital district of Pirkanmaa
  72. hospital district of Southern Ostrobothnia
  73. hospital district of North Ostrobothnia
  74. hospital district of Central Finland
  75. hospital district of Northern Savo
  76. Finnish National Public Health Institute
  77. Finnish Diabetes Association
  78. Ministry of Social Affairs and Health in Finland
  79. Finland’s Slottery Machine Association
  80. National Center on Minority Health and Health Disparities
  81. Swedish Diabetes Association
  82. Swedish Heart-Lung Foundation
  83. German Cancer Aid
  84. German Federal Ministry of Education and Research (BMBF)
  85. Cancer Research UK
  86. Spanish Ministry of Health
  87. Murcia Regional Government
  88. Swedish Research Council
  89. Danish Cancer Society
  90. Compagnia di San Paolo
  91. Asturias Regional Government
  92. Västerboten County Council
  93. Dutch Ministry of Public Health, Welfare and Sports (VWS)
  94. Netherlands Cancer Registry (NKR)
  95. LK Research Funds
  96. Dutch Prevention Funds
  97. Dutch ZON (Zorg Onderzoek Nederland)
  98. World Cancer Research Fund (WCRF)
  99. Statistics Netherlands
  100. Sicilian Regional Government
  101. AIRE -ONLUS Ragusa
  102. Imperial College Biomedical Research Centre
  103. Dutch Diabetes Research Foundation
  104. Korea Centers for Disease Control and Prevention
  105. Korea National Institute of Health
  106. State of Bavaria
  107. Ministry of Innovation, Science, Research and Technology of the state North Rhine-Westphalia
  108. Munich Center of Health Sciences (MC-Health)
  109. Ludwig-Maximilians-Universität
  110. German Research Foundation
  111. German Diabetes Association
  112. DHFD (Diabetes Hilfs- und Forschungsfonds Deutschland)
  113. Boehringer Ingelheim Foundation
  114. Integrated Research and Treatment Centre (IFB) Adiposity Diseases
  115. Free State of Saxony
  116. Netherlands Organization of Scientific Research (NWO)
  117. Dutch government
  118. Dutch Ministry of Economic Affairs
  119. Dutch Ministry of Education, Culture and Science
  120. Dutch Ministry for Health, Welfare and Sports
  121. Northern Netherlands Collaboration of Provinces (SNN)
  122. Province of Groningen
  123. University Medical Center Groningen
  124. University of Groningen
  125. Dutch Kidney Foundation
  126. British Heart Foundation
  127. National Institute of Health Research (NIHR)
  128. Data Tecnica International
  129. Finnish Heart Foundation
  130. Finnish Diabetes Foundation
  131. Ministry of Science and Technology of China
  132. National Natural Science Foundation of China
  133. Biobanking and Biomolecular Resources Research Infrastructure (BBMRI-NL)
  134. Netherlands Bioinformatics Centre (NBIC)
  135. VU University’s Institute for Health and Care Research (EMGO+ )
  136. Neuroscience Campus Amsterdam (NCA)
  137. European Science Foundation (ESF)
  138. European Science Council (ERC)
  139. Rutgers University Cell and DNA Repository
  140. Avera Institute, Sioux Falls, South Dakota/USA
  141. Chief Scientist Office of the Scottish Government
  142. AstraZeneca
  143. Knut and Alice Wallenberg Foundation
  144. Torsten and Ragnar Söderberg Foundation
  145. Karolinska Institutet
  146. Stockholm County Council
  147. National Research Foundation, Singapore
  148. Singapore National Medical Research Council
  149. Fondo Europeo para el Desarrollo Regional, Red de Centros RCMN
  150. Instituto de Salud Carlos III-RETIC
  151. Ministerio de Ciencia e Innovación (ISCII)
  152. Madrid Autonomous Community (MOIR)
  153. Eli Lilly Lab, Spain
  154. Bayer Pharmaceutical Co., Spain
  155. Fundación Mutua Madrileña 2008, Spain
  156. Ministry of Cultural Affairs of the Federal State of Mecklenburg - West Pomerania
  157. Social Ministry of the Federal State of Mecklenburg - West Pomerania
  158. Siemens Healthcare, Erlangen, Germany
  159. Federal State of Mecklenburg- West Pomerania
  160. National Health Research Institutes, Taiwan
  161. National Science Council, Taiwan
  162. National Taiwan University Hospital, Taiwan
  163. Dutch Ministry of Justice (WODC)
  164. Dutch Brain Foundation
  165. Norwegian Research Council
  166. Swedish Foundation for Strategic Research
  167. Royal Swedish Academy of Science
  168. Swedish Ministry for Higher Education
  169. Swedish Diabetes Foundation
  170. Uppsala University
  171. Uppsala University Hospital
  172. Uppsala Multidisciplinary Center for Advanced Computational Science (UPPMAX)
  173. Academia Sinica, Taipei, Taiwan
  174. Ministry of Science and Technology (Nation N)
  175. National Cancer Institute
  176. Amgen
1000 Fördernummer
  1. 24390084; 21390099; 20390185
  2. -
  3. -
  4. -
  5. -
  6. 016.156.445
  7. CVON2011-19
  8. FP7-603091-2; FP6; LSHM_CT_2006_037197; FP7/2007-2013; 279153; FP7-279143; G51; FP7-201668; FP7-305739; HEALTH-F2-2007 201681; 257082; HEALTH-F5-2011-282510; HEALTH-F4-2007-201413; LSHG-CT-2006-018947; LSHM‐CT‐ 2007‐037273; EU/QLRT-2001-01254; QLG2-CT-2002-01254
  9. WT098017; 079895; 068545/Z/02; 076113/B/04/Z; 097451/Z/11/Z; GR072960; 083270/Z/07/Z; WT098051; 084723/Z/08/Z; 090532; 098381; WT091310; 088869/B/09/Z; 075491/Z/04
  10. HHSN268201100005C; HHSN268201100006C; HHSN268201100007C; HHSN268201100008C; HHSN268201100009C; HHSN268201100010C; HHSN268201100011C; HHSN268201100012C; R01HL087641; R01HL59367; R01HL086694; T32-HL007024; HHSN268201300025C; HHSN268201300026C;HHSN268201300027C; HHSN268201300028C; HHSN268201300029C; HHSN268200900041C; N01‐HC‐25195; HHSN268201300046C; HHSN268201300047C; HHSN268201300048C; HHSN268201300049C; HHSN268201300050C; N01-HC-95159; N01-HC-95160; N01-HC-95161; N01-HC-95162; N01-HC-95163; N01-HC-95164; N01-HC-95165; N01-HC-95166; N01-HC-95167; N01-HC-95168; N01-HC-95169; UL1-TR-001079; UL1-TR-000040; DK063491; HL043851; HL080467; R01HL036310
  11. U01HG004402
  12. HHSN268200625226C; UL1RR025005; 2R01DK089174; K24DK106414; R21DK080294; U01 DK062418; 1R01DK106236-01A1; HHSN268200782096C; R01D0042157-01A; MH081802; HG002651; HG005581; HL084729; RO1CA55069; R35CA53890; R01CA80205; R01CA144034; UM1 CA182876; AG028555; AG08724; AG04563; AG10175; AG08861; DK U01-066134
  13. R01 DK078616; K24 DK080140; U01 DK085526
  14. -
  15. U01-HG-004729; U01-HG-004446; U01-HG-004424
  16. -
  17. -
  18. -
  19. G0000934; G0601261; MR/M012190/1; G0601966; G0700931; K013351; MC_UU_12019/1
  20. -
  21. -
  22. -
  23. N01AG62101; N01AG62103; N01AG62106; 1R01AG032098-01A1; NO1-AG-1–2109; 263-MA-410953
  24. -
  25. -
  26. HHSN268201300025C; HHSN268201300026C
  27. HHSN268201300027C
  28. HHSN268201300028C
  29. HHSN268201300029C
  30. HHSN268200900041C
  31. 216-1080315-0302
  32. 8875
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  55. -
  56. -
  57. 2004310
  58. -
  59. 117844; 40758; 211497; 118590; 129293; 124243
  60. 5254
  61. 40058/07
  62. 070014
  63. -
  64. 56358
  65. -
  66. 70103/06; 40058/07; 1510/31/06
  67. N02‐HL‐6‐4278
  68. -
  69. -
  70. #1-15-ACE-26
  71. -
  72. -
  73. -
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  75. -
  76. -
  77. -
  78. -
  79. -
  80. human subjects protocol
  81. -
  82. 20120197
  83. -
  84. 01GI1128; 01EO1501; K6e/2; AD2-060E; 01ZZ9603; 01ZZ0103; 01ZZ0403; 03ZIK012
  85. C8221/A19170
  86. -
  87. 6236
  88. M-2005-1112; 2009-2298; 2012-1397
  89. -
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  100. -
  101. -
  102. -
  103. 2013.81.1673
  104. 4845–301; 4851–302; 4851–307
  105. 2014-NI73001-00
  106. -
  107. -
  108. -
  109. -
  110. CRC 1052 B01;CRC 1052 B03; CRC1052/1 C05; SFB 1052; A01; C01; SPP 1629 TO 718/2-1
  111. -
  112. -
  113. -
  114. 01EO1001
  115. -
  116. 175.010.2007.006; 904-61-090; 985-10-002; 904-61-193; 480-04-004; 400-05-717; Addiction-31160008; Middelgroot-911-09-032; Spinozapremie 56-464-14192; GB-MW 940-38-011; 100-001-004; 60-60600-97-118; 261-98-710; GB-MaGW 480-01-006 and GB-MaGW 480-07-001; GB-MaGW 452-04-314 and GB-MaGW 452-06-004; 175.010.2003.005; 481-08-013; NWO 480-05-003
  117. -
  118. -
  119. -
  120. -
  121. -
  122. -
  123. -
  124. -
  125. -
  126. SP/04/002; RG/10/12/28456; PG/29605
  127. RP-PG-0407-10371
  128. -
  129. -
  130. -
  131. 2016YFC1304903
  132. 30930081; 81471013; 81170734
  133. 184.021.007
  134. 2008.024
  135. -
  136. -
  137. EU/QLRT-2001-01254; FP-006
  138. 230374
  139. NIMH U24 MH068457-06
  140. -
  141. CZB/4/276; CZB/4/710
  142. -
  143. -
  144. -
  145. -
  146. 560283
  147. 370062002
  148. 1270/2010
  149. FEDER 2FD 1997/2309; C03/08
  150. RD06/0015/0012; FIS 03/1618
  151. -
  152. S2010/BMD-2423
  153. -
  154. -
  155. -
  156. -
  157. -
  158. -
  159. -
  160. PH-100-SP-01; BS-094-PP-01; PH-100-PP-03
  161. NSC 98-2314-B-075A-002-MY3; NSC 96-2314-B-002-151; NSC 96-2314-B-002-152; NSC 98-2314-B-002-122-MY2; NSC 100-2314-B-002-115; NSC 101-2325-002-078; 101-2314-B-075A-006-MY3
  162. NTUH 98-N1266; NTUH 100-N1775; NTUH 101-N2010; NTUH 101-N; VN101-04; NTUH 101-S1784
  163. -
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  165. -
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  167. -
  168. -
  169. 2013-024
  170. -
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  172. b2011036
  173. -
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  175. CA047988; UM1CA182913
  176. -
1000 Förderprogramm
  1. -
  2. Science and Technology Incubation Program in Advanced Regions; Core Research for Evolutional Science and Technology (CREST)
  3. -
  4. -
  5. -
  6. -
  7. Genius
  8. Beta-JUDO; European Regional Development Fund (ERDF); EpiMigrant; Action on Hearing Loss; AtheroRemo; RiskyCAD; EPIGENESYS; BLUEPRINT; EUROSPAN; ENGAGE; GenomEUtwin
  9. Senior Fellowship in Basic Biomedical Science; Strategic Award; Biomedical Collections
  10. Cardiovascular Epidemiology Training; Framingham Heart Study
  11. -
  12. Roadmap for Medical Research
  13. -
  14. -
  15. -
  16. -
  17. -
  18. -
  19. -
  20. -
  21. -
  22. -
  23. Intramural Research Program
  24. Program for Promotion of Fundamental Studies in Health Sciences
  25. -
  26. -
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  54. -
  55. -
  56. -
  57. -
  58. Med Drive
  59. -
  60. EVO
  61. -
  62. Systems biology in controlled dietary interventions and cohort studies, SYSDIET
  63. -
  64. -
  65. -
  66. -
  67. -
  68. MGH Research Scholars Award
  69. Postdoctoral Research fellowship
  70. Pathway Accelerator Award
  71. -
  72. -
  73. -
  74. -
  75. -
  76. -
  77. -
  78. -
  79. -
  80. # Z01-AG000513; 09-AG-N248
  81. -
  82. -
  83. -
  84. German Obesity Biomaterial Bank
  85. -
  86. Health Research Fund (FIS)
  87. -
  88. -
  89. -
  90. -
  91. -
  92. -
  93. -
  94. -
  95. -
  96. -
  97. -
  98. -
  99. -
  100. -
  101. -
  102. -
  103. Diabetes Funds Junior Fellowship
  104. -
  105. -
  106. -
  107. -
  108. -
  109. LMUinnovativ
  110. "Obesity mechanisms”
  111. -
  112. -
  113. -
  114. -
  115. -
  116. NWO Longitudinal Survey and Panel Funding; NWO large-sized investment; Medical Research Council program; ZonMW Brainpower; ZonMw Risk Behavior and Dependence; ZonMw Culture and Health; Social Sciences Council medium-sized investment; Social Sciences Council project
  117. -
  118. -
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  133. -
  134. BioAssist/RK
  135. -
  136. -
  137. EuroSTRESS
  138. -
  139. -
  140. -
  141. -
  142. -
  143. Wallenberg Academy Fellow
  144. -
  145. Strategic Cardiovascular Program; SRP diabetes
  146. Strategic Cardiovascular Program
  147. HUJ-CREATE
  148. -
  149. -
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1000 Dateien
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