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1000 Titel
  • A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri
1000 Autor/in
  1. Baumgart, Mario |
  2. Barth, Emanuel |
  3. Savino, Aurora |
  4. Groth, Marco |
  5. Koch, Philipp |
  6. Petzold, Andreas |
  7. Arisi, Ivan |
  8. Platzer, Matthias |
  9. Marz, Manja |
  10. Cellerino, Alessandro |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-09-05
1000 Erschienen in
1000 Quellenangabe
  • 18:693
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12864-017-3951-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584509/ |
1000 Ergänzendes Material
  • https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-017-3951-8#Declarations |
  • http://www.rna.uni-jena.de/en/supplements/nothobranchius-furzeri-mirnome |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: The short-lived fish Nothobranchius furzeri is the shortest-lived vertebrate that can be cultured in captivity and was recently established as a model organism for aging research. Small non-coding RNAs, especially miRNAs, are implicated in age dependent control of gene expression. RESULTS: Here, we present a comprehensive catalogue of miRNAs and several other non-coding RNA classes (ncRNAs) for Nothobranchius furzeri. Analyzing multiple small RNA-Seq libraries, we show most of these identified miRNAs are expressed in at least one of seven Nothobranchius species. Additionally, duplication and clustering of N. furzeri miRNAs was analyzed and compared to the four fish species Danio rerio, Oryzias latipes, Gasterosteus aculeatus and Takifugu rubripes. A peculiar characteristic of N. furzeri, as compared to other teleosts, was a duplication of the miR-29 cluster. CONCLUSION: The completeness of the catalogue we provide is comparable to that of the zebrafish. This catalogue represents a basis to investigate the role of miRNAs in aging and development in this species.
1000 Sacherschließung
lokal miRNome
lokal Nothobranchius furzeri
lokal Fish miRNA evolution
lokal ncRNA
1000 Fachgruppe
  1. Medizin |
  2. Biologie |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. http://orcid.org/0000-0001-8172-1595|http://orcid.org/0000-0003-0803-8858|http://orcid.org/0000-0002-0783-7191|http://orcid.org/0000-0002-9199-8990|http://orcid.org/0000-0003-2825-7943|https://frl.publisso.de/adhoc/creator/UGV0em9sZCwgQW5kcmVhcw==|https://frl.publisso.de/adhoc/creator/QXJpc2ksIEl2YW4=|http://orcid.org/0000-0003-0596-8582|https://frl.publisso.de/adhoc/creator/TWFyeiwgTWFuamE=|http://orcid.org/0000-0003-3834-0097
1000 Label
1000 Förderer
  1. Carl Zeiss Stiftung |
  2. Thuringian Ministry for Research (TMWWDG) |
  3. German Ministry for Education and Research (BMBF) |
  4. German Research Foundation (DFG) |
  5. Scuola Normale Superiore di Pisa |
1000 Fördernummer
  1. -
  2. FSU-I-03/14
  3. 0315581
  4. BA 5576/1–1
  5. -
1000 Förderprogramm
  1. -
  2. RegenerAging (Thuringian country programme ProExzellenz)
  3. JenAge
  4. -
  5. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Carl Zeiss Stiftung |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Thuringian Ministry for Research (TMWWDG) |
    1000 Förderprogramm RegenerAging (Thuringian country programme ProExzellenz)
    1000 Fördernummer FSU-I-03/14
  3. 1000 joinedFunding-child
    1000 Förderer German Ministry for Education and Research (BMBF) |
    1000 Förderprogramm JenAge
    1000 Fördernummer 0315581
  4. 1000 joinedFunding-child
    1000 Förderer German Research Foundation (DFG) |
    1000 Förderprogramm -
    1000 Fördernummer BA 5576/1–1
  5. 1000 joinedFunding-child
    1000 Förderer Scuola Normale Superiore di Pisa |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6408314.rdf
1000 Erstellt am 2018-06-14T14:00:30.853+0200
1000 Erstellt von 285
1000 beschreibt frl:6408314
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Thu Jan 30 16:38:25 CET 2020
1000 Objekt bearb. Wed Jun 20 12:01:26 CEST 2018
1000 Vgl. frl:6408314
1000 Oai Id
  1. oai:frl.publisso.de:frl:6408314 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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