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Günther-Seyfert2018_Article_TheFirstLineOfDefenceInsightsI.pdf 1,34MB
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1000 Titel
  • The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells
1000 Autor/in
  1. Günther, Juliane |
  2. Seyfert, Hans-Martin |
1000 Erscheinungsjahr 2018
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2018-09-04
1000 Erschienen in
1000 Quellenangabe
  • 2018: 1863-2300
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2018
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00281-018-0701-1 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Epithelial tissues cover most of the external and internal surfaces of the body and its organs. Inevitably, these tissues serve as first line of defence against inorganic, organic, and microbial intruders. Epithelial cells are the main cell type of these tissues. Besides their function as cellular barrier, there is growing evidence that epithelial cells are of particular relevance as initial sensors of danger and also as executers of adequate defence responses. These cells feature various essential functions to maintain tissue integrity in health and disease. In this review, we survey some of the different innate immune functions of epithelial cells in mucosal tissues being constantly exposed to a plethora of harmless contaminants but also of pathogens. We discuss how epithelial cells avoid inadequate immune responses in such conditions. In particular, we will focus on the diverse types and mechanisms of phagocytosis used by epithelial cells to not only maintain homeostasis but to also harness the host response against invading pathogens.
1000 Fachgruppe
  1. Biologie |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/R8O8bnRoZXIsIEp1bGlhbmU=|https://frl.publisso.de/adhoc/creator/U2V5ZmVydCwgSGFucy1NYXJ0aW4=
1000 Label
1000 Förderer
  1. Deutsche Forschungsgemeinschaft (DFG) |
  2. Leibniz Institute for Farm Animal Biology (FBN) |
1000 Fördernummer
  1. GU 1487/1-1
  2. -
1000 Förderprogramm
  1. -
  2. Open Access Fund
1000 Dateien
  1. The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Deutsche Forschungsgemeinschaft (DFG) |
    1000 Förderprogramm -
    1000 Fördernummer GU 1487/1-1
  2. 1000 joinedFunding-child
    1000 Förderer Leibniz Institute for Farm Animal Biology (FBN) |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6410302.rdf
1000 Erstellt am 2018-09-25T14:32:45.495+0200
1000 Erstellt von 122
1000 beschreibt frl:6410302
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Thu Jan 30 16:54:40 CET 2020
1000 Objekt bearb. Tue Sep 25 14:33:35 CEST 2018
1000 Vgl. frl:6410302
1000 Oai Id
  1. oai:frl.publisso.de:frl:6410302 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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