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Rampelli-et-al_2018_Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity.pdf 2,49MB
WeightNameValue
1000 Titel
  • Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity
1000 Autor/in
  1. Rampelli, Simone |
  2. Günther, Kathrin |
  3. Turroni, Silvia |
  4. Wolters, Maike |
  5. Veidebaum, Toomas |
  6. Kourides, Yiannis |
  7. Molnar, Dénes |
  8. Lissner, Lauren |
  9. Benítez-Paez, Alfonso |
  10. Sanz, Yolanda |
  11. Fraterman, Arno |
  12. Michels, Nathalie |
  13. Brigidi, Patrizia |
  14. Candela, Marco |
  15. Ahrens, Wolfgang |
1000 Erscheinungsjahr 2018
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2018-12-07
1000 Erschienen in
1000 Quellenangabe
  • 1: 222
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2018
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1038/s42003-018-0221-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286349/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/s42003-018-0221-5#Sec17 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • It is widely accepted that the intestinal microbiome is connected to obesity, as key mediator of the diet impact on the host metabolic and immunological status. To investigate whether the individual gut microbiome has a potential in predicting the onset and progression of diseases, here we characterized the faecal microbiota of 70 children in a two-time point prospective study, within a four-year window. All children had normal weight at the beginning of this study, but 36 of them gained excessive weight at the subsequent check-up. Microbiome data were analysed together with the hosts’ diet information, physical activity, and inflammatory parameters. We find that the gut microbiota structures were stratified into a discrete number of groups, characterized by different biodiversity that correlates with inflammatory markers and dietary habits, regardless of age, gender, and body weight. Collectively, our data underscore the importance of the microbiome–host–diet configuration as a possible predictor of obesity.
1000 Sacherschließung
lokal Obesity
lokal Microbiome
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
  3. Ernährungswissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. http://orcid.org/0000-0002-5655-6695|https://frl.publisso.de/adhoc/creator/R8O8bnRoZXIsIEthdGhyaW4=|http://orcid.org/0000-0003-2345-9482|http://orcid.org/0000-0002-4943-2141|https://frl.publisso.de/adhoc/creator/VmVpZGViYXVtLCBUb29tYXM=|https://frl.publisso.de/adhoc/creator/S291cmlkZXMsIFlpYW5uaXM=|https://frl.publisso.de/adhoc/creator/TW9sbmFyLCBEw6luZXM=|https://frl.publisso.de/adhoc/creator/TGlzc25lciwgTGF1cmVu|https://frl.publisso.de/adhoc/creator/QmVuw610ZXotUGFleiwgQWxmb25zbw==|http://orcid.org/0000-0002-1615-1976|https://frl.publisso.de/adhoc/creator/RnJhdGVybWFuLCBBcm5v|https://frl.publisso.de/adhoc/creator/TWljaGVscywgTmF0aGFsaWU=|https://frl.publisso.de/adhoc/creator/QnJpZ2lkaSwgUGF0cml6aWE=|https://frl.publisso.de/adhoc/creator/Q2FuZGVsYSwgTWFyY28=|http://orcid.org/0000-0003-3777-570X
1000 Förderer
  1. European Commission |
1000 Fördernummer
  1. 016181 (FOOD); 266044 (KBBE 2010-14); 613979
1000 Förderprogramm
  1. Sixth Framework Programme; Seventh Framework Programme
1000 Dateien
  1. Rampelli-et-al_2018_Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Commission |
    1000 Förderprogramm Sixth Framework Programme; Seventh Framework Programme
    1000 Fördernummer 016181 (FOOD); 266044 (KBBE 2010-14); 613979
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6411754.rdf
1000 Erstellt am 2018-12-12T15:03:01.426+0100
1000 Erstellt von 266
1000 beschreibt frl:6411754
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Fri Dec 14 12:14:11 CET 2018
1000 Objekt bearb. Fri Dec 14 12:13:01 CET 2018
1000 Vgl. frl:6411754
1000 Oai Id
  1. oai:frl.publisso.de:frl:6411754 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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