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WeightNameValue
1000 Titel
  • Fructose in Breast Milk Is Positively Associated with Infant Body Composition at 6 Months of Age
1000 Autor/in
  1. Goran, Michael I. |
  2. Martin, Ashley A. |
  3. Alderete, Tanya |
  4. Fujiwara, Hideji |
  5. Fields, David A. |
1000 Erscheinungsjahr 2017
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-02-16
1000 Erschienen in
1000 Quellenangabe
  • 9(2):146
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.3390/nu9020146 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331577/ |
1000 Ergänzendes Material
  • https://www.mdpi.com/2072-6643/9/2/146#supplementary |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Dietary sugars have been shown to promote excess adiposity among children and adults; however, no study has examined fructose in human milk and its effects on body composition during infancy. Twenty-five mother–infant dyads attended clinical visits to the Oklahoma Health Sciences Center at 1 and 6 months of infant age. Infants were exclusively breastfed for 6 months and sugars in breast milk (i.e., fructose, glucose, lactose) were measured by Liquid chromatography-mass spectrometry (LC-MS/MS) and glucose oxidase. Infant body composition was assessed using dual-energy X-ray absorptiometry at 1 and 6 months. Multiple linear regression was used to examine associations between breast milk sugars and infant body composition at 6 months of age. Fructose, glucose, and lactose were present in breast milk and stable across visits (means = 6.7 μg/mL, 255.2 μg/mL, and 7.6 g/dL, respectively). Despite its very low concentration, fructose was the only sugar significantly associated with infant body composition. A 1-μg/mL higher breast milk fructose was associated with a 257 g higher body weight (p = 0.02), 170 g higher lean mass (p = 0.01), 131 g higher fat mass (p = 0.05), and 5 g higher bone mineral content (p = 0.03). In conclusion, fructose is detectable in human breast milk and is positively associated with all components of body composition at 6 months of age.
1000 Sacherschließung
lokal breast milk
lokal fructose
lokal maternal programming
lokal breastfeeding
lokal added sugars
1000 Fachgruppe
  1. Medizin |
  2. Ernährungswissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/R29yYW4sIE1pY2hhZWwgSS4=|https://frl.publisso.de/adhoc/creator/TWFydGluLCBBc2hsZXkgQS4=|http://orcid.org/0000-0002-7751-9543|https://frl.publisso.de/adhoc/creator/RnVqaXdhcmEsIEhpZGVqaQ==|https://frl.publisso.de/adhoc/creator/RmllbGRzLCBEYXZpZCBBLg==
1000 Förderer
  1. Mead Johnson Nutrition |
  2. Harold Hamm Diabetes Center at the University of Oklahoma Health Sciences Center |
  3. National Institute of Health (NIH) |
1000 Fördernummer
  1. -
  2. -
  3. GM103422; DK056341; DK020579
1000 Förderprogramm
  1. -
  2. -
  3. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Mead Johnson Nutrition |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Harold Hamm Diabetes Center at the University of Oklahoma Health Sciences Center |
    1000 Förderprogramm -
    1000 Fördernummer -
  3. 1000 joinedFunding-child
    1000 Förderer National Institute of Health (NIH) |
    1000 Förderprogramm -
    1000 Fördernummer GM103422; DK056341; DK020579
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6412348.rdf
1000 Erstellt am 2019-01-29T12:46:44.410+0100
1000 Erstellt von 122
1000 beschreibt frl:6412348
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Tue Jan 29 12:48:49 CET 2019
1000 Objekt bearb. Tue Jan 29 12:48:30 CET 2019
1000 Vgl. frl:6412348
1000 Oai Id
  1. oai:frl.publisso.de:frl:6412348 |
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