Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice

  1. Grimaldi, Keith A.
  2. van Ommen, Ben
  3. Ordovas, Jose M.
  4. Parnell, Laurence D.
  5. Mathers, John C.
  6. Bendik, Igor
  7. Brennan, Lorraine
  8. Celis-Morales, Carlos
  9. Cirillo, Elisa
  10. Daniel, Hannelore
  11. de Kok, Brenda
  12. El-Sohemy, Ahmed
  13. Fairweather-Tait, Susan J.
  14. Fallaize, Rosalind
  15. Fenech, Michael
  16. Ferguson, Lynnette R.
  17. Gibney, Eileen R.
  18. Gibney, Mike
  19. Gjelstad, Ingrid M. F.
  20. Kaput, Jim
  21. Karlsen, Anette S.
  22. Kolossa, Silvia
  23. Lovegrove, Julie
  24. Macready, Anna L.
  25. Marsaux, Cyril F. M.
  26. Alfredo Martinez, J.
  27. Milagro, Fermin
  28. Navas-Carretero, Santiago
  29. Roche, Helen M.
  30. Saris, Wim H. M.
  31. Traczyk, Iwona
  32. van Kranen, Henk
  33. Verschuren, Lars
  34. Virgili, Fabio
  35. Weber, Peter
  36. Bouwman, Jildau ORCID logo

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WeightNameValue
1000 Titel
  • Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice
1000 Autor/in
  1. Grimaldi, Keith A. |
  2. van Ommen, Ben |
  3. Ordovas, Jose M. |
  4. Parnell, Laurence D. |
  5. Mathers, John C. |
  6. Bendik, Igor |
  7. Brennan, Lorraine |
  8. Celis-Morales, Carlos |
  9. Cirillo, Elisa |
  10. Daniel, Hannelore |
  11. de Kok, Brenda |
  12. El-Sohemy, Ahmed |
  13. Fairweather-Tait, Susan J. |
  14. Fallaize, Rosalind |
  15. Fenech, Michael |
  16. Ferguson, Lynnette R. |
  17. Gibney, Eileen R. |
  18. Gibney, Mike |
  19. Gjelstad, Ingrid M. F. |
  20. Kaput, Jim |
  21. Karlsen, Anette S. |
  22. Kolossa, Silvia |
  23. Lovegrove, Julie |
  24. Macready, Anna L. |
  25. Marsaux, Cyril F. M. |
  26. Alfredo Martinez, J. |
  27. Milagro, Fermin |
  28. Navas-Carretero, Santiago |
  29. Roche, Helen M. |
  30. Saris, Wim H. M. |
  31. Traczyk, Iwona |
  32. van Kranen, Henk |
  33. Verschuren, Lars |
  34. Virgili, Fabio |
  35. Weber, Peter |
  36. Bouwman, Jildau |
1000 Erscheinungsjahr 2017
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-12-15
1000 Erschienen in
1000 Quellenangabe
  • 12:35
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12263-017-0584-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732517/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Nutrigenetic research examines the effects of inter-individual differences in genotype on responses to nutrients and other food components, in the context of health and of nutrient requirements. A practical application of nutrigenetics is the use of personal genetic information to guide recommendations for dietary choices that are more efficacious at the individual or genetic subgroup level relative to generic dietary advice. Nutrigenetics is unregulated, with no defined standards, beyond some commercially adopted codes of practice. Only a few official nutrition-related professional bodies have embraced the subject, and, consequently, there is a lack of educational resources or guidance for implementation of the outcomes of nutrigenetic research. To avoid misuse and to protect the public, personalised nutrigenetic advice and information should be based on clear evidence of validity grounded in a careful and defensible interpretation of outcomes from nutrigenetic research studies. Evidence requirements are clearly stated and assessed within the context of state-of-the-art ‘evidence-based nutrition’. We have developed and present here a draft framework that can be used to assess the strength of the evidence for scientific validity of nutrigenetic knowledge and whether ‘actionable’. In addition, we propose that this framework be used as the basis for developing transparent and scientifically sound advice to the public based on nutrigenetic tests. We feel that although this area is still in its infancy, minimal guidelines are required. Though these guidelines are based on semi-quantitative data, they should stimulate debate on their utility. This framework will be revised biennially, as knowledge on the subject increases.
1000 Sacherschließung
lokal Health
lokal Genotype
lokal Gene-environment interaction
lokal Personalised nutrition
lokal Genetic variants
lokal Dietary advice
lokal Framework
lokal Nutrigenetics
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/R3JpbWFsZGksIEtlaXRoIEEu|https://frl.publisso.de/adhoc/creator/dmFuIE9tbWVuLCBCZW4=|https://frl.publisso.de/adhoc/creator/T3Jkb3ZhcywgSm9zZSBNLg==|https://frl.publisso.de/adhoc/creator/UGFybmVsbCwgTGF1cmVuY2UgRC4=|https://frl.publisso.de/adhoc/creator/TWF0aGVycywgSm9obiBDLg==|https://frl.publisso.de/adhoc/creator/QmVuZGlrLCBJZ29y|https://frl.publisso.de/adhoc/creator/QnJlbm5hbiwgTG9ycmFpbmU=|https://frl.publisso.de/adhoc/creator/Q2VsaXMtTW9yYWxlcywgQ2FybG9z|https://frl.publisso.de/adhoc/creator/Q2lyaWxsbywgRWxpc2E=|https://frl.publisso.de/adhoc/creator/RGFuaWVsLCBIYW5uZWxvcmU=|https://frl.publisso.de/adhoc/creator/ZGUgS29rLCBCcmVuZGE=|https://frl.publisso.de/adhoc/creator/RWwtU29oZW15LCBBaG1lZA==|https://frl.publisso.de/adhoc/creator/RmFpcndlYXRoZXItVGFpdCwgU3VzYW4gSi4=|https://frl.publisso.de/adhoc/creator/RmFsbGFpemUsIFJvc2FsaW5k|https://frl.publisso.de/adhoc/creator/RmVuZWNoLCBNaWNoYWVs|https://frl.publisso.de/adhoc/creator/RmVyZ3Vzb24sIEx5bm5ldHRlIFIu|https://frl.publisso.de/adhoc/creator/R2libmV5LCBFaWxlZW4gUi4=|https://frl.publisso.de/adhoc/creator/R2libmV5LCBNaWtl|https://frl.publisso.de/adhoc/creator/R2plbHN0YWQsIEluZ3JpZCBNLiBGLg==|https://frl.publisso.de/adhoc/creator/S2FwdXQsIEppbQ==|https://frl.publisso.de/adhoc/creator/S2FybHNlbiwgQW5ldHRlIFMu|https://frl.publisso.de/adhoc/creator/S29sb3NzYSwgU2lsdmlh|https://frl.publisso.de/adhoc/creator/TG92ZWdyb3ZlLCBKdWxpZQ==|https://frl.publisso.de/adhoc/creator/TWFjcmVhZHksIEFubmEgTC4=|https://frl.publisso.de/adhoc/creator/TWFyc2F1eCwgQ3lyaWwgRi4gTS4=|https://frl.publisso.de/adhoc/creator/QWxmcmVkbyBNYXJ0aW5leiwgSi4=|https://frl.publisso.de/adhoc/creator/TWlsYWdybywgRmVybWlu|https://frl.publisso.de/adhoc/creator/TmF2YXMtQ2FycmV0ZXJvLCBTYW50aWFnbw==|https://frl.publisso.de/adhoc/creator/Um9jaGUsIEhlbGVuIE0u|https://frl.publisso.de/adhoc/creator/U2FyaXMsIFdpbSBILiBNLg==|https://frl.publisso.de/adhoc/creator/VHJhY3p5aywgSXdvbmE=|https://frl.publisso.de/adhoc/creator/dmFuIEtyYW5lbiwgSGVuaw==|https://frl.publisso.de/adhoc/creator/VmVyc2NodXJlbiwgTGFycw==|https://frl.publisso.de/adhoc/creator/VmlyZ2lsaSwgRmFiaW8=|https://frl.publisso.de/adhoc/creator/V2ViZXIsIFBldGVy|http://orcid.org/0000-0002-9396-0646
1000 Label
1000 Förderer
  1. European Commission |
1000 Fördernummer
  1. 265494
1000 Förderprogramm
  1. 7th Framework Programme for Research and Technological Development
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer European Commission |
    1000 Förderprogramm 7th Framework Programme for Research and Technological Development
    1000 Fördernummer 265494
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6412475.rdf
1000 Erstellt am 2019-01-31T12:53:29.120+0100
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1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Tue Oct 19 13:48:21 CEST 2021
1000 Objekt bearb. Tue Oct 19 13:48:20 CEST 2021
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