Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort

  1. Caputo, Mahrrouz
  2. Horn, Johannes
  3. Karch, André
  4. Akmatov, Manas
  5. Becher, Heiko
  6. Braun, Bettina
  7. Brenner, Hermann
  8. Castell, Stefanie
  9. Fischer, Beate
  10. Giani, Guido
  11. Günther, Kathrin
  12. Hoffmann, Barbara
  13. Jöckel, Karl-Heinz
  14. Keil, Thomas
  15. Klüppelholz, Birgit
  16. Krist, Lilian
  17. Leitzmann, Michael F.
  18. Lieb, Wolfgang
  19. Linseisen, Jakob
  20. Meisinger, Christa
  21. Moebus, Susanne
  22. Obi, Nadia
  23. Pischon, Tobias
  24. Schipf, Sabine
  25. Schmidt, Börge
  26. Sievers, Claudia
  27. Steinbrecher, Astrid
  28. Völzke, Henry
  29. Mikolajczyk, Rafael

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WeightNameValue
1000 Titel
  • Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort
1000 Autor/in
  1. Caputo, Mahrrouz |
  2. Horn, Johannes |
  3. Karch, André |
  4. Akmatov, Manas |
  5. Becher, Heiko |
  6. Braun, Bettina |
  7. Brenner, Hermann |
  8. Castell, Stefanie |
  9. Fischer, Beate |
  10. Giani, Guido |
  11. Günther, Kathrin |
  12. Hoffmann, Barbara |
  13. Jöckel, Karl-Heinz |
  14. Keil, Thomas |
  15. Klüppelholz, Birgit |
  16. Krist, Lilian |
  17. Leitzmann, Michael F. |
  18. Lieb, Wolfgang |
  19. Linseisen, Jakob |
  20. Meisinger, Christa |
  21. Moebus, Susanne |
  22. Obi, Nadia |
  23. Pischon, Tobias |
  24. Schipf, Sabine |
  25. Schmidt, Börge |
  26. Sievers, Claudia |
  27. Steinbrecher, Astrid |
  28. Völzke, Henry |
  29. Mikolajczyk, Rafael |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-01-30
1000 Erschienen in
1000 Quellenangabe
  • 19:99
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1186/s12879-019-3691-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354372/ |
1000 Ergänzendes Material
  • https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-3691-2#Decs |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Until now, herpes zoster (HZ)-related disease burden in Germany has been estimated based on health insurance data and clinical findings. However, the validity of self-reported HZ is unclear. This study investigated the validity of self-reported herpes zoster (HZ) and its complication postherpetic neuralgia (PHN) using data from the pretest studies of the German National Cohort (GNC) in comparison with estimates based on health insurance data. METHODS: Data of 4751 participants aged between 20 and 69 years from two pretest studies of the GNC carried out in 2011 and 2012 were used. Based on self-reports of physician-diagnosed HZ and PHN, age- and sex-specific HZ incidence rates and PHN proportions were estimated. For comparison, estimates based on statutory health insurance data from the German population were considered. RESULTS: Eleven percent (95%-CI, 10.4 to 12.3, n = 539) of the participants reported at least one HZ episode in their lifetime. Our estimated age-specific HZ incidence rates were lower than previous estimates based on statutory health insurance data. The PHN proportion in participants older than 50 years was 5.9% (1.9 to 13.9%), which was in line with estimates based on health insurance data. CONCLUSION: As age- and sex-specific patterns were comparable with that in health insurance data, self-reported diagnosis of HZ seems to be a valid instrument for overall disease trends. Possible reasons for observed differences in incidence rates are recall bias in self-reported data or overestimation in health insurance data.
1000 Sacherschließung
lokal Postherpetic neuralgia
lokal Validity
lokal Herpes zoster
lokal German National Cohort
lokal Self-reports
lokal Incidence
1000 Fachgruppe
  1. Medizin |
  2. Gesundheitswesen |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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  1. Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort
    Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort
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1000 @id frl:6413198.rdf
1000 Erstellt am 2019-03-04T12:12:02.556+0100
1000 Erstellt von 266
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1000 Zuletzt bearbeitet 2020-01-31T00:52:34.764+0100
1000 Objekt bearb. Mon Mar 11 13:24:32 CET 2019
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