fnins-13-00384.pdf 180,96KB
1000 Titel
  • The Interplay Between Stress, Inflammation, and Emotional Attention: Relevance for Depression
1000 Autor/in
  1. Maydych, Viktoriya |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-04-24
1000 Erschienen in
1000 Quellenangabe
  • 13:384
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • |
  • |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Depression is among the most significant public mental health issues. A growing body of research implicates inflammation in the etiology and pathophysiology of depression. Yet, the results are somewhat inconsistent, leading to burgeoning attempts to identify associations between components of innate immune system involved in inflammation and specific symptoms of depression, including attention to emotional information. Negative attentional bias, defined as a tendency to direct attention toward negatively valenced information, is one of the core cognitive features of depression and is reliably demonstrated in depressed and vulnerable individuals. Altered attentional processing of emotional information and immunological changes are often precipitated by stressful events. Psychological stress triggers inflammatory activity and affective-cognitive changes that play a critical role in the onset, maintenance, and recurrence of depression. Using various designs, recent studies have reported a positive relationship between markers of inflammation and negative attentional bias on behavioral and neural levels, suggesting that the association between inflammation and emotional attention might represent a neurobiological pathway linking stress and depression. This mini-review summarizes current research on the reciprocal relationships between different types of stressors, emotional attention, inflammation, and depression, and discusses potential neurobiological mechanisms underlying these interactions. The integration provided aims to contribute toward understanding how biological and psychological processes interact to influence depression outcomes.
1000 Sacherschließung
lokal psychological stress
lokal depressive disorders
lokal attentional bias
lokal emotional attention
lokal negative bias
lokal inflammation
lokal cytokines
lokal depression
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
1000 Label
1000 Förderer
  1. Leibniz-Gemeinschaft |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. Open Access Fund
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Leibniz-Gemeinschaft |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6415582.rdf
1000 Erstellt am 2019-08-02T10:00:44.670+0200
1000 Erstellt von 254
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1000 Zuletzt bearbeitet Mon Aug 12 11:12:50 CEST 2019
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