Download
s12970-018-0213-3.pdf 614,64KB
WeightNameValue
1000 Titel
  • An attempt to induce an immunomodulatory effect in rowers with spirulina extract
1000 Autor/in
  1. Juszkiewicz, Artur |
  2. Basta, Piotr |
  3. Petriczko, Elżbieta |
  4. Machaliński, Bogusław |
  5. Trzeciak, Jerzy |
  6. Łuczkowska, Karolina |
  7. Skarpańska-Stejnborn, Anna |
1000 Erscheinungsjahr 2018
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2018-02-20
1000 Erschienen in
1000 Quellenangabe
  • 15:9
1000 Copyrightjahr
  • 2018
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12970-018-0213-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819236/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: The aim of this study was to analyze the response of selected components of the immune system in rowers to maximal physical exercise, and to verify if this response can be modulated by supplementation with spirulina (cyanobacterium Spirulina platensis). METHOD: The double-blind study included 19 members of the Polish Rowing Team. The subjects were randomly assigned to the supplemented group (n = 10), receiving 1500 mg of spirulina extract for 6 weeks, or to the placebo group (n = 9). The participants performed a 2000-m test on a rowing ergometer at the beginning (1st examination) and at the end of the supplementation period (2nd examination). Blood samples were obtained from the antecubital vein prior to each exercise test, 1 min after completing the test, and after a 24-h recovery period. Subpopulations of T regulatory lymphocytes (Tregs) [CD4+/CD25+/CD127-], cytotoxic lymphocytes (CTLs) [CD8+/TCRαβ+], natural killer (NK) cells [CD3-/CD16+/CD56+] and TCRδγ-positive (Tδγ) cells were determined by means of flow cytometry. RESULTS: On the 2nd examination, athletes from the supplemented group showed neither a post-exercise increase in Treg count nor a post-recovery decrease in Tδγ cell count (both observed in the placebo group), and presented with significantly lower values of Treg/CTL prior to and after the exercise. During the same examination, rowers from the placebo group showed a significant post-recovery increase in Treg/(NK + Tδγ + CTL) ratio, which was absent in the supplemented group. CONCLUSION: The results of this study imply that supplementation with spirulina extract may protect athletes against a deficit in immune function (especially, anti-infectious function) associated with strenuous exercise, and may cause a beneficial shift in “overtraining threshold” preventing a radical deterioration of immunity.
1000 Sacherschließung
lokal Spirulina
lokal Inflammation
lokal Rowers
lokal Flow cytometry
lokal Strenuous exercise
lokal Supplementation
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SnVzemtpZXdpY3osIEFydHVy|https://frl.publisso.de/adhoc/uri/QmFzdGEsIFBpb3Ry|https://frl.publisso.de/adhoc/uri/UGV0cmljemtvLCBFbMW8YmlldGE=|https://frl.publisso.de/adhoc/uri/TWFjaGFsacWEc2tpLCBCb2d1c8WCYXc=|https://frl.publisso.de/adhoc/uri/VHJ6ZWNpYWssIEplcnp5|https://frl.publisso.de/adhoc/uri/xYF1Y3prb3dza2EsIEthcm9saW5h|https://frl.publisso.de/adhoc/uri/U2thcnBhxYRza2EtU3Rlam5ib3JuLCBBbm5h
1000 Label
1000 Förderer
  1. Polish Ministry of Science and Higher Education |
1000 Fördernummer
  1. 0034/RS3/2015/53
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Polish Ministry of Science and Higher Education |
    1000 Förderprogramm -
    1000 Fördernummer 0034/RS3/2015/53
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6416635.rdf
1000 Erstellt am 2019-10-07T12:48:00.380+0200
1000 Erstellt von 218
1000 beschreibt frl:6416635
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Fri Jan 31 01:22:23 CET 2020
1000 Objekt bearb. Mon Oct 07 12:48:56 CEST 2019
1000 Vgl. frl:6416635
1000 Oai Id
  1. oai:frl.publisso.de:frl:6416635 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source