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1000 Titel
  • COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses
1000 Autor/in
  1. Shereen, Muhammad Adnan |
  2. Khan, Suliman |
  3. Kazmi, Abeer |
  4. Bashir, Nadia |
  5. Siddique, Rabeea |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-03-16
1000 Erschienen in
1000 Quellenangabe
  • 24:91-98
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1016/j.jare.2020.03.005 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113610/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, however, the rapid human to human transfer has been confirmed widely. There is no clinically approved antiviral drug or vaccine available to be used against COVID-19. However, few broad-spectrum antiviral drugs have been evaluated against COVID-19 in clinical trials, resulted in clinical recovery. In the current review, we summarize and comparatively analyze the emergence and pathogenicity of COVID-19 infection and previous human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV). We also discuss the approaches for developing effective vaccines and therapeutic combinations to cope with this viral outbreak.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Origin
lokal Outbreak
lokal Coronaviruses
lokal Spread
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U2hlcmVlbiwgTXVoYW1tYWQgQWRuYW4=|https://orcid.org/0000-0003-4954-0748|https://frl.publisso.de/adhoc/uri/S2F6bWksIEFiZWVy|https://frl.publisso.de/adhoc/uri/QmFzaGlyLCBOYWRpYQ==|https://frl.publisso.de/adhoc/uri/U2lkZGlxdWUsIFJhYmVlYQ==
1000 Label
1000 Förderer
  1. Second Affiliated Hospital of Zhengzhou University |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Second Affiliated Hospital of Zhengzhou University |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6419836.rdf
1000 Erstellt am 2020-04-07T13:47:10.474+0200
1000 Erstellt von 122
1000 beschreibt frl:6419836
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Tue Apr 07 13:48:43 CEST 2020
1000 Objekt bearb. Tue Apr 07 13:48:25 CEST 2020
1000 Vgl. frl:6419836
1000 Oai Id
  1. oai:frl.publisso.de:frl:6419836 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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