A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe

  1. Borobia, Alberto M. ORCID logo
  2. Carcas, Antonio J.
  3. Arnalich, Francisco ORCID logo
  4. Álvarez-Sala, Rodolfo
  5. Monserrat-Villatoro, Jaime
  6. Quintana, Manuel
  7. Figueira, Juan C.
  8. Torres Santos-Olmo, Rosario Maria ORCID logo
  9. García-Rodríguez, Julio
  10. Martín-Vega, Alberto
  11. Buño, Antonio
  12. Ramírez, Elena ORCID logo
  13. Martínez-Alés, Gonzalo
  14. Garcia-Arenzana, Nicolas ORCID logo
  15. Núñez, M. Concepción
  16. Martí-de-Gracia, Milagros
  17. Moreno Ramos, Francisco
  18. Reinoso-Barbero, Francisco ORCID logo
  19. Martin-Quiros, Alejandro
  20. Rivera Núñez, Angélica
  21. Mingorance, Jesus ORCID logo
  22. Carpio Segura, Carlos J.
  23. Prieto Arribas, Daniel
  24. Rey Cuevas, Esther
  25. Prados Sánchez, Concepción
  26. Rios, Juan J.
  27. Hernán, Miguel A.
  28. Frias Iniesta, Jesus A. ORCID logo
  29. Arribas, José R.
  30. COVID@HULP Working Group

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WeightNameValue
1000 Titel
  • A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe
1000 Autor/in
  1. Borobia, Alberto M. |
  2. Carcas, Antonio J. |
  3. Arnalich, Francisco |
  4. Álvarez-Sala, Rodolfo |
  5. Monserrat-Villatoro, Jaime |
  6. Quintana, Manuel |
  7. Figueira, Juan C. |
  8. Torres Santos-Olmo, Rosario Maria |
  9. García-Rodríguez, Julio |
  10. Martín-Vega, Alberto |
  11. Buño, Antonio |
  12. Ramírez, Elena |
  13. Martínez-Alés, Gonzalo |
  14. Garcia-Arenzana, Nicolas |
  15. Núñez, M. Concepción |
  16. Martí-de-Gracia, Milagros |
  17. Moreno Ramos, Francisco |
  18. Reinoso-Barbero, Francisco |
  19. Martin-Quiros, Alejandro |
  20. Rivera Núñez, Angélica |
  21. Mingorance, Jesus |
  22. Carpio Segura, Carlos J. |
  23. Prieto Arribas, Daniel |
  24. Rey Cuevas, Esther |
  25. Prados Sánchez, Concepción |
  26. Rios, Juan J. |
  27. Hernán, Miguel A. |
  28. Frias Iniesta, Jesus A. |
  29. Arribas, José R. |
1000 Mitwirkende/r
  1. COVID@HULP Working Group |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-06-04
1000 Erschienen in
1000 Quellenangabe
  • 9(6):1733
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3390/jcm9061733 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Since the confirmation of the first patient infected with SARS-CoV-2 in Spain in January 2020, the epidemic has grown rapidly, with the greatest impact on the region of Madrid. This article describes the first 2226 adult patients with COVID-19, consecutively admitted to La Paz University Hospital in Madrid. METHODS: Our cohort included all patients consecutively hospitalized who had a final outcome (death or discharge) in a 1286-bed hospital of Madrid (Spain) from 25 February (first case admitted) to 19 April 2020. The data were manually entered into an electronic case report form, which was monitored prior to the analysis. RESULTS: We consecutively included 2226 adult patients admitted to the hospital who either died (460) or were discharged (1766). The patients’ median age was 61 years, and 51.8% were women. The most common comorbidity was arterial hypertension (41.3%), and the most common symptom on admission was fever (71.2%). The median time from disease onset to hospital admission was 6 days. The overall mortality was 20.7% and was higher in men (26.6% vs. 15.1%). Seventy-five patients with a final outcome were transferred to the intensive care unit (ICU) (3.4%). Most patients admitted to the ICU were men, and the median age was 64 years. Baseline laboratory values on admission were consistent with an impaired immune-inflammatory profile. CONCLUSIONS: We provide a description of the first large cohort of hospitalized patients with COVID-19 in Europe. Advanced age, male sex, the presence of comorbidities and abnormal laboratory values were more common among the patients with fatal outcomes.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Europe
lokal SARS-CoV-2
lokal Spain
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-8584-3263|https://frl.publisso.de/adhoc/uri/Q2FyY2FzLCBBbnRvbmlvIEou|https://orcid.org/0000-0001-7001-3067|https://frl.publisso.de/adhoc/uri/w4FsdmFyZXotU2FsYSwgUm9kb2xmbw==|https://frl.publisso.de/adhoc/uri/TW9uc2VycmF0LVZpbGxhdG9ybywgSmFpbWU=|https://frl.publisso.de/adhoc/uri/UXVpbnRhbmEsIE1hbnVlbA==|https://frl.publisso.de/adhoc/uri/RmlndWVpcmEsIEp1YW4gQy4=|https://orcid.org/0000-0002-8479-3671|https://frl.publisso.de/adhoc/uri/R2FyY8OtYS1Sb2Ryw61ndWV6LCBKdWxpbw==|https://frl.publisso.de/adhoc/uri/TWFydMOtbi1WZWdhLCBBbGJlcnRv|https://frl.publisso.de/adhoc/uri/QnXDsW8sIEFudG9uaW8=|https://orcid.org/0000-0002-4052-8876|https://frl.publisso.de/adhoc/uri/TWFydMOtbmV6LUFsw6lzLCBHb256YWxv|https://orcid.org/0000-0002-1952-095X|https://frl.publisso.de/adhoc/uri/TsO6w7FleiwgTS4gQ29uY2VwY2nDs24=|https://frl.publisso.de/adhoc/uri/TWFydMOtLWRlLUdyYWNpYSwgTWlsYWdyb3M=|https://frl.publisso.de/adhoc/uri/TW9yZW5vIFJhbW9zLCBGcmFuY2lzY28=|https://orcid.org/0000-0002-1605-3831|https://frl.publisso.de/adhoc/uri/TWFydGluLVF1aXJvcywgQWxlamFuZHJv|https://frl.publisso.de/adhoc/uri/Uml2ZXJhIE7DusOxZXosIEFuZ8OpbGljYQ==|https://orcid.org/0000-0001-6173-5711|https://frl.publisso.de/adhoc/uri/Q2FycGlvIFNlZ3VyYSwgQ2FybG9zIEou|https://frl.publisso.de/adhoc/uri/UHJpZXRvIEFycmliYXMsIERhbmllbA==|https://frl.publisso.de/adhoc/uri/UmV5IEN1ZXZhcywgRXN0aGVy|https://frl.publisso.de/adhoc/uri/UHJhZG9zIFPDoW5jaGV6LCBDb25jZXBjacOzbg==|https://frl.publisso.de/adhoc/uri/UmlvcywgSnVhbiBKLg==|https://frl.publisso.de/adhoc/uri/SGVybsOhbiwgTWlndWVsIEEu|https://orcid.org/0000-0001-9538-9677|https://frl.publisso.de/adhoc/uri/QXJyaWJhcywgSm9zw6kgUi4=|https://frl.publisso.de/adhoc/uri/Q09WSURASFVMUCBXb3JraW5nIEdyb3Vw
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1000 Erstellt am 2020-06-04T08:54:58.664+0200
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