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Laboratory preparedness for SARS-CoV-2 testing in India: Harnessing a network of Virus Research & Diagnostic Laboratories

  1. Gupta, Nivedita
  2. Potdar, Varsha
  3. Praharaj, Ira
  4. Giri, Sidhartha
  5. Sapkal, Gajanan
  6. Yadav, Pragya
  7. Choudhary, Manohar
  8. Dar, Lalit
  9. Sugunan, A
  10. Kaur, Harmanmeet
  11. Munivenkatappa, Ashok
  12. Shastri, Jayanthi
  13. Kaveri, Krishnasamy
  14. Dutta, Shanta
  15. Malhotra, Bharti
  16. Jain, Amita
  17. Nagamani, Kammilli
  18. Shantala, G
  19. Raut, Sharmila
  20. Vegad, M
  21. Sharma, Ajanta
  22. Choudhary, Aashish
  23. Brijwal, Megha
  24. Balakrishnan, Anukumar
  25. Manjunatha, Jayaswamy
  26. Pathak, Manish
  27. Srinivasan, Sivasubramanian
  28. Banu, Hasina
  29. Sharma, Himanshu
  30. Jain, Parul
  31. Sunita, Pakalpati
  32. Ambica, R
  33. Fageria, Babita
  34. Patel, Disha
  35. Rajbongshi, Gitika
  36. Vijay, Neetu
  37. Narayan, Jitendra
  38. Aggarwal, Neeraj
  39. Nagar, Anu
  40. Gangakhedkar, Raman
  41. Abraham, Priya

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WeightNameValue
1000 Titel
  • Laboratory preparedness for SARS-CoV-2 testing in India: Harnessing a network of Virus Research & Diagnostic Laboratories
1000 Autor/in
  1. Gupta, Nivedita |
  2. Potdar, Varsha |
  3. Praharaj, Ira |
  4. Giri, Sidhartha |
  5. Sapkal, Gajanan |
  6. Yadav, Pragya |
  7. Choudhary, Manohar |
  8. Dar, Lalit |
  9. Sugunan, A |
  10. Kaur, Harmanmeet |
  11. Munivenkatappa, Ashok |
  12. Shastri, Jayanthi |
  13. Kaveri, Krishnasamy |
  14. Dutta, Shanta |
  15. Malhotra, Bharti |
  16. Jain, Amita |
  17. Nagamani, Kammilli |
  18. Shantala, G |
  19. Raut, Sharmila |
  20. Vegad, M |
  21. Sharma, Ajanta |
  22. Choudhary, Aashish |
  23. Brijwal, Megha |
  24. Balakrishnan, Anukumar |
  25. Manjunatha, Jayaswamy |
  26. Pathak, Manish |
  27. Srinivasan, Sivasubramanian |
  28. Banu, Hasina |
  29. Sharma, Himanshu |
  30. Jain, Parul |
  31. Sunita, Pakalpati |
  32. Ambica, R |
  33. Fageria, Babita |
  34. Patel, Disha |
  35. Rajbongshi, Gitika |
  36. Vijay, Neetu |
  37. Narayan, Jitendra |
  38. Aggarwal, Neeraj |
  39. Nagar, Anu |
  40. Gangakhedkar, Raman |
  41. Abraham, Priya |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-04-28
1000 Erschienen in
1000 Quellenangabe
  • 151(2):216-225
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.4103/ijmr.ijmr_594_20 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258754/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND & OBJECTIVES: An outbreak of respiratory illness of unknown aetiology was reported from Hubei province of Wuhan, People's Republic of China, in December 2019. The outbreak was attributed to a novel coronavirus (CoV), named as severe acute respiratory syndrome (SARS)-CoV-2 and the disease as COVID-19. Within one month, cases were reported from 25 countries. In view of the novel viral strain with reported high morbidity, establishing early countrywide diagnosis to detect imported cases became critical. Here we describe the role of a countrywide network of VRDLs in early diagnosis of COVID-19. METHODS: The Indian Council of Medical Research (ICMR)-National Institute of Virology (NIV), Pune, established screening as well as confirmatory assays for SARS-CoV-2. A total of 13 VRDLs were provided with the E gene screening real-time reverse transcription-polymerase chain reaction (rRT-PCR) assay. VRDLs were selected on the basis of their presence near an international airport/seaport and their past performance. The case definition for testing included all individuals with travel history to Wuhan and symptomatic individuals with travel history to other parts of China. This was later expanded to include symptomatic individuals returning from Singapore, Japan, Hong Kong, Thailand and South Korea. RESULTS: Within a week of standardization of the test at NIV, all VRDLs could initiate testing for SARS-CoV-2. Till February 29, 2020, a total of 2,913 samples were tested. This included both 654 individuals quarantined in the two camps and others fitting within the case definition. The quarantined individuals were tested twice - at days 0 and 14. All tested negative on both occasions. Only three individuals belonging to different districts in Kerala were found to be positive. INTERPRETATION & CONCLUSIONS: Sudden emergence of SARS-CoV-2 and its potential to cause a pandemic posed an unsurmountable challenge to the public health system of India. However, concerted efforts of various arms of the Government of India resulted in a well-coordinated action at each level. India has successfully demonstrated its ability to establish quick diagnosis of SARS-CoV-2 at NIV, Pune, and the testing VRDLs.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal quality control
lokal quarantine
lokal severe acute respiratory syndrome-CoV-2
lokal diagnosis
lokal preparedness
lokal Virus Research and Diagnostic Laboratory
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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1000 Label
1000 Förderer
  1. Department of Health Research, India |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. Ministry of Health & Family Welfare
1000 Dateien
  2. Open Access Statement IJMR
    Open Access Statement IJMR
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Department of Health Research, India |
    1000 Förderprogramm Ministry of Health & Family Welfare
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6424175.rdf
1000 Erstellt am 2020-11-11T14:48:21.699+0100
1000 Erstellt von 218
1000 beschreibt frl:6424175
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Tue Nov 17 09:21:05 CET 2020
1000 Objekt bearb. Tue Nov 17 09:21:05 CET 2020
1000 Vgl. frl:6424175
1000 Oai Id
  1. oai:frl.publisso.de:frl:6424175 |
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