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WeightNameValue
1000 Titel
  • Mitochondria in the Nuclei of Rat Myocardial Cells
1000 Autor/in
  1. Eldarov, Chupalav M. |
  2. Vangely, Irina M. |
  3. Vays, Valeriya B. |
  4. Sheval, Eugene V. |
  5. Holtze, Susanne |
  6. Hildebrandt, Thomas Bernd |
  7. Kolosova, Nataliya G |
  8. Plotnikov, Egor |
  9. Zorov, Dmitry B. |
  10. Bakeeva, Lora E. |
  11. Skulachev, Vladimir P. |
1000 Erscheinungsjahr 2020
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-03-14
1000 Erschienen in
1000 Quellenangabe
  • 9(3):712
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3390/cells9030712 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140638/ |
1000 Ergänzendes Material
  • https://www.mdpi.com/2073-4409/9/3/712#supplementary |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Electron microscopic study of cardiomyocytes taken from healthy Wistar and OXYS rats and naked mole rats (Heterocephalus glaber) revealed mitochondria in nuclei that lacked part of the nuclear envelope. The direct interaction of mitochondria with nucleoplasm is shown. The statistical analysis of the occurrence of mitochondria in cardiomyocyte nuclei showed that the percentage of nuclei with mitochondria was roughly around 1%, and did not show age and species dependency. Confocal microscopy of normal rat cardiac myocytes revealed a branched mitochondrial network in the vicinity of nuclei with an organization different than that of interfibrillar mitochondria. This mitochondrial network was energetically functional because it carried the membrane potential that responded by oscillatory mode after photodynamic challenge. We suggest that the presence of functional mitochondria in the nucleus is not only a consequence of certain pathologies but rather represents a normal biological phenomenon involved in mitochondrial/nuclear interactions.
1000 Sacherschließung
lokal healthy cells
lokal electron and confocal microscopy
lokal heart
lokal intranuclear mitochondria
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RWxkYXJvdiwgQ2h1cGFsYXYgTS4=|https://frl.publisso.de/adhoc/uri/VmFuZ2VseSwgSXJpbmEgTS4=|https://frl.publisso.de/adhoc/uri/VmF5cywgVmFsZXJpeWEgQi4=|https://frl.publisso.de/adhoc/uri/U2hldmFsLCBFdWdlbmUgVi4=|https://orcid.org/0000-0002-4654-1916|https://orcid.org/0000-0001-8685-4733|https://orcid.org/0000-0003-2398-8544|https://orcid.org/0000-0003-2838-3704|https://frl.publisso.de/adhoc/uri/Wm9yb3YsIERtaXRyeSBCLg==|https://frl.publisso.de/adhoc/uri/QmFrZWV2YSwgTG9yYSBFLg==|https://frl.publisso.de/adhoc/uri/U2t1bGFjaGV2LCBWbGFkaW1pciBQLg==
1000 Label
1000 Förderer
  1. Russian Science Support Foundation |
  2. Russian Foundation of Basic Research |
1000 Fördernummer
  1. 19-14-00173
  2. 19-04-00578
1000 Förderprogramm
  1. confocal microscopy
  2. electron microscopy
1000 Dateien
  1. Mitochondria in the Nuclei of Rat Myocardial Cells
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Russian Science Support Foundation |
    1000 Förderprogramm confocal microscopy
    1000 Fördernummer 19-14-00173
  2. 1000 joinedFunding-child
    1000 Förderer Russian Foundation of Basic Research |
    1000 Förderprogramm electron microscopy
    1000 Fördernummer 19-04-00578
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6426562.rdf
1000 Erstellt am 2021-03-31T08:34:34.125+0200
1000 Erstellt von 122
1000 beschreibt frl:6426562
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Wed Mar 31 08:39:57 CEST 2021
1000 Objekt bearb. Wed Mar 31 08:38:11 CEST 2021
1000 Vgl. frl:6426562
1000 Oai Id
  1. oai:frl.publisso.de:frl:6426562 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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