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WeightNameValue
1000 Titel
  • Recent Advances on Nanomaterials to COVID‐19 Management: A Systematic Review on Antiviral/Virucidal Agents and Mechanisms of SARS‐CoV‐2 Inhibition/Inactivation
1000 Autor/in
  1. Azevedo De Carvalho, Anna Paula |
  2. Conte-Junior, Carlos |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-22
1000 Erschienen in
1000 Quellenangabe
  • Early View (2000115)
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1002/gch2.202000115 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994982/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The current pandemic of coronavirus disease 2019 (COVID‐19) is recognized as a public health emergency of worldwide concern. Nanomaterials can be effectively used to detect, capture/inactivate or inhibit coronavirus cell entry/replication in the human host cell, preventing infection. Their potential for nanovaccines, immunoengineering, diagnosis, repurposing medication, and disinfectant surfaces targeting the novel coronavirus (SARS‐CoV‐2) is highlighted. In this systematic review the aim is to present an unbiased view of which and how nanomaterials can reduce the spread of COVID‐19. Herein, the focus is on SARS‐CoV‐2, analyzing 46 articles retrieved before December 31, 2020. The interface between nanomaterials is described, and the main mechanisms to inhibit SARS‐CoV‐2 pathogenesis and viral inactivation are also discussed. Nanocarbons, biopolymeric, copper, and silver nanoparticles are potential antiviral and virucidal agents toward self‐cleaning and reusable filter media and surfaces (e.g., facial masks), drug administration, vaccines, and immunodiagnostic assays. Trends in toxicology research and safety tests can help fill the main gaps in the literature and overcome health surveillance's challenges. Phytochemicals delivery by nanocarriers also stand out as candidates to target and bio‐friendly therapy. Nanocellulose might fill in the gaps. Future research using nanomaterials targeting novel therapies/prophylaxis measures to COVID‐19 and future outbreaks is discussed.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal bioactive compounds
lokal nanomedicine
lokal self-cleaning surfaces
lokal polymeric nanoparticles
lokal cell mechanisms
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-9258-5947|https://orcid.org/0000-0001-6133-5080
1000 Label
1000 Förderer
  1. Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro |
  2. Conselho Nacional de Desenvolvimento Científico e Tecnológico |
1000 Fördernummer
  1. E-26/2543334/2019; E-26/010.000.984/2019; E-26/010.000148/2020; E-26/200.060/2020
  2. 311422/2016-0
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro |
    1000 Förderprogramm -
    1000 Fördernummer E-26/2543334/2019; E-26/010.000.984/2019; E-26/010.000148/2020; E-26/200.060/2020
  2. 1000 joinedFunding-child
    1000 Förderer Conselho Nacional de Desenvolvimento Científico e Tecnológico |
    1000 Förderprogramm -
    1000 Fördernummer 311422/2016-0
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6427109.rdf
1000 Erstellt am 2021-04-29T09:12:10.229+0200
1000 Erstellt von 218
1000 beschreibt frl:6427109
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Mon May 31 10:57:06 CEST 2021
1000 Objekt bearb. Mon May 31 10:56:50 CEST 2021
1000 Vgl. frl:6427109
1000 Oai Id
  1. oai:frl.publisso.de:frl:6427109 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
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