Application of two job indices for general occupational demands in a pooled analysis of case–control studies on lung cancer

  1. Hovanec, Jan
  2. Siemiatycki, Jack
  3. Conway, David I.
  4. Olsson, Ann
  5. Guenel, Pascal
  6. Luce, Daniele
  7. Jöckel, Karl-Heinz
  8. Pohlabeln, Hermann ORCID logo
  9. Ahrens, Wolfgang ORCID logo
  10. Karrasch, Stefan
  11. Wichmann, Heinz-Erich
  12. Gustavsson, Per
  13. Consonni, Dario
  14. Merletti, Franco
  15. Richiardi, Lorenzo
  16. Simonato, Lorenzo
  17. Fortes, Cristina
  18. Parent, Marie-Elise
  19. McLaughin, John R.
  20. Demers, Paul
  21. Landi, Maria Teresa
  22. Caporaso, Neil
  23. Fernandez-Tardon, Guillermo
  24. Zaridze, David
  25. Świątkowska, Beata
  26. Pandics, Tamas
  27. Lissowska, Jolanta
  28. Fabianova, Eleonora
  29. Field, John K.
  30. Mates, Dana
  31. Bencko, Vladimir
  32. Foretova, Lenka
  33. Janout, Vladimir
  34. Kromhout, Hans
  35. Vermeulen, Roel
  36. Boffetta, Paolo
  37. Straif, Kurt
  38. Schüz, Joachim
  39. Casjens, Swaantje
  40. Pesch, Beate
  41. Brüning, Thomas
  42. Behrens, Thomas

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1000 Titel
  • Application of two job indices for general occupational demands in a pooled analysis of case–control studies on lung cancer
1000 Autor/in
  1. Hovanec, Jan |
  2. Siemiatycki, Jack |
  3. Conway, David I. |
  4. Olsson, Ann |
  5. Guenel, Pascal |
  6. Luce, Daniele |
  7. Jöckel, Karl-Heinz |
  8. Pohlabeln, Hermann |
  9. Ahrens, Wolfgang |
  10. Karrasch, Stefan |
  11. Wichmann, Heinz-Erich |
  12. Gustavsson, Per |
  13. Consonni, Dario |
  14. Merletti, Franco |
  15. Richiardi, Lorenzo |
  16. Simonato, Lorenzo |
  17. Fortes, Cristina |
  18. Parent, Marie-Elise |
  19. McLaughin, John R. |
  20. Demers, Paul |
  21. Landi, Maria Teresa |
  22. Caporaso, Neil |
  23. Fernandez-Tardon, Guillermo |
  24. Zaridze, David |
  25. Świątkowska, Beata |
  26. Pandics, Tamas |
  27. Lissowska, Jolanta |
  28. Fabianova, Eleonora |
  29. Field, John K. |
  30. Mates, Dana |
  31. Bencko, Vladimir |
  32. Foretova, Lenka |
  33. Janout, Vladimir |
  34. Kromhout, Hans |
  35. Vermeulen, Roel |
  36. Boffetta, Paolo |
  37. Straif, Kurt |
  38. Schüz, Joachim |
  39. Casjens, Swaantje |
  40. Pesch, Beate |
  41. Brüning, Thomas |
  42. Behrens, Thomas |
1000 Erscheinungsjahr 2021
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-05-04
1000 Erschienen in
1000 Quellenangabe
  • 47(6):475-481
1000 FRL-Sammlung
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.5271/sjweh.3967 |
1000 Ergänzendes Material
  • https://www.sjweh.fi/download_online.php?abstract_id=3967&file_nro=1 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • OBJECTIVES: We investigated general job demands as a risk factor for lung cancer as well as their role in the association between occupational prestige and lung cancer. METHODS: In 13 case–control studies on lung cancer, as part of the international SYNERGY project, we applied indices for physical (PHI) and psychosocial (PSI) job demands – each with four categories (high to low). We estimated odds ratios (OR) and 95% confidence intervals (CI) for lung cancer by unconditional logistic regression, separately for men and women and adjusted for study centre, age, smoking behavior, and former employment in occupations with potential exposure to carcinogens. Further, we investigated, whether higher risks among men with low occupational prestige (Treiman’s Standard International Occupational Prestige Scale) were affected by adjustment for the job indices. RESULTS: In 30 355 men and 7371 women, we found increased risks (OR) for lung cancer with high relative to low job demands in both men [PHI 1.74 (95% CI 1.56–1.93), PSI 1.33 (95% CI 1.17–1.51)] and women [PHI 1.62 (95% CI 1.24–2.11), PSI 1.31 (95% CI 1.09–1.56)]. OR for lung cancer among men with low occupational prestige were slightly reduced when adjusting for PHI [low versus high prestige OR from 1.44 (95% CI 1.32–1.58) to 1.30 (95% CI 1.17–1.45)], but not PSI. CONCLUSIONS: Higher physical job demands were associated with increased risks of lung cancer, while associations for higher psychosocial demands were less strong. In contrast to physical demands, psychosocial demands did not contribute to clarify the association of occupational prestige and lung cancer.
1000 Sacherschließung
lokal Smoking
lokal Tumor Subtype
lokal case–control
lokal Job index
lokal Social Prestige
lokal Psychosocial
lokal cancer
lokal occupational demand
lokal lung cancer
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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  1. Deutsche Gesetzliche Unfallversicherung |
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  1. FP 271
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    1000 Förderer Deutsche Gesetzliche Unfallversicherung |
    1000 Förderprogramm -
    1000 Fördernummer FP 271
1000 Objektart article
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1000 Erstellt am 2021-10-07T11:09:38.016+0200
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1000 Zuletzt bearbeitet 2021-11-04T12:18:25.654+0100
1000 Objekt bearb. Thu Nov 04 12:17:17 CET 2021
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