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Tanoey-et-al_2022_Birth Order, Caesarean Section, or Daycare Attendance.pdf 3,02MB
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1000 Titel
  • Birth Order, Caesarean Section, or Daycare Attendance in Relation to Child- and Adult-Onset Type 1 Diabetes: Results from the German National Cohort
1000 Autor/in
  1. Tanoey, Justine |
  2. Baechle, Christina |
  3. Brenner, Hermann |
  4. Deckert, Andreas |
  5. Fricke, Julia |
  6. Günther, Kathrin |
  7. Karch, André |
  8. Keil, Thomas |
  9. Kluttig, Alexander |
  10. Leitzmann, Michael |
  11. Mikolajczyk, Rafael |
  12. Obi, Nadia |
  13. Pischon, Tobias |
  14. Schikowski, Tamara |
  15. Schipf, Sabine |
  16. Schulze, Matthias B. |
  17. Sedlmeier, Anja |
  18. Moreno Velásquez, Ilais |
  19. Weber, Katharina S |
  20. Völzke, Henry |
  21. Ahrens, Wolfgang |
  22. Gastell, Sylvia |
  23. Holleczek, Bernd |
  24. Jöckel, Karl-Heinz |
  25. Katzke, Verena |
  26. Lieb, Wolfgang |
  27. Michels, Karin B. |
  28. Schmidt, Börge |
  29. Teismann, Henning |
  30. Becher, Heiko |
1000 Erscheinungsjahr 2022
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2022-08-31
1000 Erschienen in
1000 Quellenangabe
  • 19(17):10880
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2022
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3390/ijerph191710880 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517906/ |
1000 Ergänzendes Material
  • https://www.mdpi.com/1660-4601/19/17/10880/htm#app1-ijerph-19-10880 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • (1) BACKGROUND: Global incidence of type 1 diabetes (T1D) is rising and nearly half occurred in adults. However, it is unclear if certain early-life childhood T1D risk factors were also associated with adult-onset T1D. This study aimed to assess associations between birth order, delivery mode or daycare attendance and type 1 diabetes (T1D) risk in a population-based cohort and whether these were similar for childhood- and adult-onset T1D (cut-off age 15); (2) METHODS: Data were obtained from the German National Cohort (NAKO Gesundheitsstudie) baseline assessment. Self-reported diabetes was classified as T1D if: diagnosis age ≤ 40 years and has been receiving insulin treatment since less than one year after diagnosis. Cox regression was applied for T1D risk analysis; (3) RESULTS: Analyses included 101,411 participants (100 childhood- and 271 adult-onset T1D cases). Compared to “only-children”, HRs for second- or later-born individuals were 0.70 (95% CI = 0.50–0.96) and 0.65 (95% CI = 0.45–0.94), respectively, regardless of parental diabetes, migration background, birth year and perinatal factors. In further analyses, higher birth order reduced T1D risk in children and adults born in recent decades. Caesarean section and daycare attendance showed no clear associations with T1D risk; (4) CONCLUSIONS: Birth order should be considered in both children and adults’ T1D risk assessment for early detection.
1000 Sacherschließung
lokal NAKO
lokal delivery mode
lokal offspring
lokal late-onset
lokal perinatal
lokal adult-onset
lokal autoimmune
lokal sex
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/VGFub2V5LCBKdXN0aW5l|https://orcid.org/0000-0003-1262-7591|https://orcid.org/0000-0002-6129-1572|https://orcid.org/0000-0003-0526-6249|https://orcid.org/0000-0002-7625-474X|https://frl.publisso.de/adhoc/uri/R8O8bnRoZXIsIEthdGhyaW4=|https://frl.publisso.de/adhoc/uri/S2FyY2gsIEFuZHLDqQ==|https://orcid.org/0000-0002-9108-3360|https://frl.publisso.de/adhoc/uri/S2x1dHRpZywgQWxleGFuZGVy|https://frl.publisso.de/adhoc/uri/TGVpdHptYW5uLCBNaWNoYWVs|https://orcid.org/0000-0003-1271-7204|https://orcid.org/0000-0002-0903-9142|https://orcid.org/0000-0003-1568-767X|https://frl.publisso.de/adhoc/uri/U2NoaWtvd3NraSwgVGFtYXJh|https://frl.publisso.de/adhoc/uri/U2NoaXBmLCBTYWJpbmU=|https://orcid.org/0000-0002-0830-5277|https://orcid.org/0000-0002-7564-3065|https://frl.publisso.de/adhoc/uri/TW9yZW5vIFZlbMOhc3F1ZXosIElsYWlz|https://orcid.org/0000-0002-5555-2641|https://frl.publisso.de/adhoc/uri/VsO2bHprZSwgSGVucnk=|https://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/uri/R2FzdGVsbCwgU3lsdmlh|https://orcid.org/0000-0001-8759-4371|https://frl.publisso.de/adhoc/uri/SsO2Y2tlbCwgS2FybC1IZWlueg==|https://frl.publisso.de/adhoc/uri/S2F0emtlLCBWZXJlbmE=|https://orcid.org/0000-0003-2544-4460|https://frl.publisso.de/adhoc/uri/TWljaGVscywgS2FyaW4gQi4=|https://frl.publisso.de/adhoc/uri/U2NobWlkdCwgQsO2cmdl|https://orcid.org/0000-0001-5807-5572|https://orcid.org/0000-0002-8808-6667
1000 (Academic) Editor
1000 Label
1000 Förderer
  1. Bundesministerium für Bildung und Forschung |
1000 Fördernummer
  1. 01ER1901A PERGOLA2; 01ER1301A/B/C; 01ER1511D
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Bildung und Forschung |
    1000 Förderprogramm -
    1000 Fördernummer 01ER1901A PERGOLA2; 01ER1301A/B/C; 01ER1511D
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6438345.rdf
1000 Erstellt am 2022-11-10T13:53:21.708+0100
1000 Erstellt von 266
1000 beschreibt frl:6438345
1000 Bearbeitet von 317
1000 Zuletzt bearbeitet Thu Dec 15 11:48:49 CET 2022
1000 Objekt bearb. Thu Dec 15 11:48:32 CET 2022
1000 Vgl. frl:6438345
1000 Oai Id
  1. oai:frl.publisso.de:frl:6438345 |
1000 Sichtbarkeit Metadaten public
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