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1000 Titel
  • Accelerate postoperative management after scoliosis surgery in healthy and impaired children: intravenous opioid therapy versus epidural therapy
1000 Autor/in
  1. Dinter, Katharina |
  2. Bretschneider, Henriette |
  3. Zwingenberger, Stefan |
  4. Disch, Alexander |
  5. Osmers, Anne |
  6. Vicent, Oliver |
  7. Thielemann, Falk |
  8. Seifert, Jens |
  9. Bernstein, Peter |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-24
1000 Erschienen in
1000 Quellenangabe
  • 143(1):301-309
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00402-021-03972-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886629/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Postoperative pain is a major concern following scoliosis surgery. CEA (continuous epidural analgesia) is established in postoperative pain therapy as well as intravenous patient-controlled analgesia (IV-PCA). The purpose of this study was to compare the clinical outcomes of both methods.!##!Methods!#!We retrospectively studied 175 children between 8 and 18 years who were subject to posterior scoliosis correction and fusion. Two main cohorts were formed: CEA with local anesthetic and opioids, and IV-PCA with opioids. Both groups further comprised two sub-cohorts: those who were mentally and/or physically healthy (H; n = 93 vs. n = 30) and those who were impaired (I; n = 26 vs. n = 26). The outcome parameters were the demand for pain medication, parameters of mobilization, and the presence of adverse reactions.!##!Results!#!Healthy children who received CEA started mobilization 1 day earlier than children with IV-PCA (p = 0.002). First postsurgical defecation was seen earlier in all children who received CEA in both groups (H; Day 4 vs. Day 5, p = 0.011, I; Day 3 vs. Day 5, p = 0.044). Healthy children who received CEA were discharged from hospital 4 days earlier than their IV-PCA counterparts (p < 0.001). No statistically significant difference in postoperative nausea nor in vomiting was identified between groups. Transient neurological irritations were seen in 9.7% of the patients in the CEA group.!##!Conclusions!#!CEA provides appropriate pain management after scoliosis surgery, regardless of the patient's mental status. It allows earlier postoperative defecation for all patients , as well as shorter hospitalization and an earlier mobilization for healthy patients.
1000 Sacherschließung
lokal Humans [MeSH]
lokal Analgesia, Epidural/adverse effects [MeSH]
lokal Retrospective Studies [MeSH]
lokal Analgesia, Epidural/methods [MeSH]
lokal Analgesia, Patient-Controlled/methods [MeSH]
lokal Epidural analgesia
lokal Analgesics, Opioid/therapeutic use [MeSH]
lokal Pain, Postoperative/drug therapy [MeSH]
lokal Scoliosis surgery
lokal Pain
lokal Orthopaedic Surgery
lokal Recovery
lokal Pain, Postoperative/etiology [MeSH]
lokal Scoliosis/surgery [MeSH]
lokal Postoperative Nausea and Vomiting/drug therapy [MeSH]
lokal Child [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-7212-0931|https://frl.publisso.de/adhoc/uri/QnJldHNjaG5laWRlciwgSGVucmlldHRl|https://frl.publisso.de/adhoc/uri/WndpbmdlbmJlcmdlciwgU3RlZmFu|https://frl.publisso.de/adhoc/uri/RGlzY2gsIEFsZXhhbmRlcg==|https://frl.publisso.de/adhoc/uri/T3NtZXJzLCBBbm5l|https://frl.publisso.de/adhoc/uri/VmljZW50LCBPbGl2ZXI=|https://frl.publisso.de/adhoc/uri/VGhpZWxlbWFubiwgRmFsaw==|https://frl.publisso.de/adhoc/uri/U2VpZmVydCwgSmVucw==|https://frl.publisso.de/adhoc/uri/QmVybnN0ZWluLCBQZXRlcg==
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1000 Erstellt am 2023-04-28T15:49:24.347+0200
1000 Erstellt von 322
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1000 Zuletzt bearbeitet 2023-10-20T20:30:42.310+0200
1000 Objekt bearb. Fri Oct 20 20:30:42 CEST 2023
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