Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB)

  1. Jazmati, Tarek ORCID logo
  2. Hamprecht, Axel ORCID logo
  3. Jazmati, Nathalie ORCID logo

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1000 Titel
  • Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB)
1000 Autor/in
  1. Jazmati, Tarek |
  2. Hamprecht, Axel |
  3. Jazmati, Nathalie |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-27
1000 Erschienen in
1000 Quellenangabe
  • 40(11):2431-2436
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s10096-021-04250-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520522/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • To establish the optimal detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB), the performance of four different screening methods has been investigated: stool samples without (A) and with (B) pre-enrichment and rectal swabs without (C) and with (D) pre-enrichment were contrasted. Pre-enrichment approaches (B and D) increased the detection of 3GCREB carriers by 29.4% (20/68 3GCREB carriers only found using pre-enrichment, p < 0.0001) compared to direct plating approaches (A and C). Moreover, the study demonstrates a minor advantage of stool samples in contrast to rectal swabs in both cases (with and without pre-enrichment). Registration number: DRKS00022520, 24 July 2020.
1000 Sacherschließung
lokal Humans [MeSH]
lokal Cephalosporins/pharmacology [MeSH]
lokal Enterobacteriaceae/classification [MeSH]
lokal Medical Microbiology
lokal Enterobacteriaceae/genetics [MeSH]
lokal Brief Report
lokal Carrier State/microbiology [MeSH]
lokal Drug Resistance, Bacterial [MeSH]
lokal Enterobacteriaceae Infections/microbiology [MeSH]
lokal Anti-Bacterial Agents/pharmacology [MeSH]
lokal Enterobacteriaceae/drug effects [MeSH]
lokal Feces/microbiology [MeSH]
lokal Internal Medicine
lokal Rectum/microbiology [MeSH]
lokal Enterobacteriaceae/isolation
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-1241-4257|https://orcid.org/0000-0003-1449-5780|https://orcid.org/0000-0003-4746-7970
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