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1000 Titel
  • Effects of nasal high flow on nocturnal hypercapnia, sleep, and sympathovagal balance in patients with neuromuscular disorders
1000 Autor/in
  1. Meyer, Anna Christina |
  2. Spiesshoefer, Jens |
  3. Siebers, Nina Christina |
  4. Heidbreder, Anna |
  5. Thiedemann, Christian |
  6. Schneider, Hartmut |
  7. Braun, Andrew T. |
  8. Randerath, Winfried |
  9. Young, Peter |
  10. Dreher, Michael |
  11. Boentert, Matthias |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-12-02
1000 Erschienen in
1000 Quellenangabe
  • 25(3):1441-1451
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11325-020-02263-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708892/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!In neuromuscular disorders (NMD), inspiratory muscle weakness may cause sleep-related hypoventilation requiring non-invasive ventilation (NIV). Alternatively, nasal high flow therapy (NHF) may ameliorate mild nocturnal hypercapnia (NH) through washout of anatomical dead space and generation of positive airway pressure. Ventilatory support by NIV or NHF might have favourable short-term effects on sympathovagal balance (SVB). This study comparatively investigated the effects of NHF and NIV on sleep-related breathing and SVB in NMD patients with evolving NH.!##!Methods!#!Transcutaneous CO!##!Results!#!Compared with no treatment, NHF20 and NHF50 did not significantly change p!##!Conclusions!#!NHF does not correct sleep-disordered breathing in NMD patients with NH. Both NHF and NIV exert no immediate effects on SVB.
1000 Sacherschließung
lokal Female [MeSH]
lokal Sympathetic drive
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Sleep/physiology [MeSH]
lokal Middle Aged [MeSH]
lokal Polysomnography [MeSH]
lokal Hypercapnia/physiopathology [MeSH]
lokal Sleep Breathing Physiology and Disorders • Original Article
lokal Nasal high flow therapy
lokal Hypercapnia/therapy [MeSH]
lokal Male [MeSH]
lokal Neuromuscular Diseases/physiopathology [MeSH]
lokal Hypercapnia
lokal Translational respiratory physiology
lokal Blood Pressure/physiology [MeSH]
lokal Heart Rate/physiology [MeSH]
lokal Noninvasive Ventilation [MeSH]
lokal Oxygen Inhalation Therapy/methods [MeSH]
lokal Neuromuscular disorders
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TWV5ZXIsIEFubmEgQ2hyaXN0aW5h|https://frl.publisso.de/adhoc/uri/U3BpZXNzaG9lZmVyLCBKZW5z|https://frl.publisso.de/adhoc/uri/U2llYmVycywgTmluYSBDaHJpc3RpbmE=|https://frl.publisso.de/adhoc/uri/SGVpZGJyZWRlciwgQW5uYQ==|https://frl.publisso.de/adhoc/uri/VGhpZWRlbWFubiwgQ2hyaXN0aWFu|https://frl.publisso.de/adhoc/uri/U2NobmVpZGVyLCBIYXJ0bXV0|https://frl.publisso.de/adhoc/uri/QnJhdW4sIEFuZHJldyBULg==|https://frl.publisso.de/adhoc/uri/UmFuZGVyYXRoLCBXaW5mcmllZA==|https://frl.publisso.de/adhoc/uri/WW91bmcsIFBldGVy|https://frl.publisso.de/adhoc/uri/RHJlaGVyLCBNaWNoYWVs|https://orcid.org/0000-0001-6133-1397
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1000 Erstellt am 2023-11-17T17:53:03.288+0100
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1000 Zuletzt bearbeitet 2023-12-01T08:17:49.123+0100
1000 Objekt bearb. Fri Dec 01 08:17:49 CET 2023
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