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1000 Titel
  • Association of laparoscopic colectomy versus open colectomy on the long-term health-related quality of life of colon cancer survivors
1000 Autor/in
  1. Thong, Melissa |
  2. Jansen, Lina |
  3. Chang-Claude, Jenny |
  4. Hoffmeister, Michael |
  5. Brenner, Hermann |
  6. Arndt, Volker |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-01-28
1000 Erschienen in
1000 Quellenangabe
  • 34(12):5593-5603
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00464-019-07360-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144161/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Laparoscopic colectomy (LC) is a less invasive alternative to open colectomy (OC) in the treatment of stage I-III colon cancer. Research on the long-term (5-year post-diagnosis) health-related quality of life (HRQOL) of LC patients is scarce. Our study aimed to compare the long-term HRQOL and psychological well-being of stage I-III colon cancer survivors treated either with LC or OC.!##!Methods!#!This study used a German population-based cohort of patients treated with either LC (n = 86) or OC (n = 980). LC patients were matched to OC patients using a propensity score. At 5-year follow-up, patients completed assessments on HRQOL (EORTC QLQ-C30 and EORTC QLQ-CR29) and psychological well-being (distress and disease/treatment burden). Least square mean scores of HRQOL were derived using linear regression. Proportions of patients with moderate/high distress and disease/treatment burden were compared with Chi-square tests.!##!Results!#!In total, 81 LC patients were matched to 156 OC patients. Generally, LC patients had HRQOL comparable to OC patients, albeit LC patients reported significantly better body image (87.1 versus 81.0, p = 0.03). Distress levels were generally low and comparable between the two groups, even though LC patients were more likely to experience disease recurrence (16% versus 7%, p = 0.02) than OC patients. OC patients were more likely to feel moderate/high levels of burden associated with the treatment (72% versus 56%, p = 0.01) and the time after treatment completion (43% versus 28%, p = 0.02).!##!Conclusion!#!LC patients reported comparable long-term HRQOL outcomes but higher levels of psychological well-being than OC patients 5 years after diagnosis, even though LC was associated with higher risk of disease recurrence.
1000 Sacherschließung
lokal Cancer Survivors/psychology [MeSH]
lokal Female [MeSH]
lokal Cost of Illness [MeSH]
lokal Health-related quality of life
lokal Aged [MeSH]
lokal Laparoscopy [MeSH]
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal Population based
lokal Neoplasm Recurrence, Local/surgery [MeSH]
lokal Cohort Studies [MeSH]
lokal Article
lokal Male [MeSH]
lokal Colonic Neoplasms/psychology [MeSH]
lokal Colectomy/psychology [MeSH]
lokal Quality of Life [MeSH]
lokal Chi-Square Distribution [MeSH]
lokal Laparoscopy
lokal Propensity Score [MeSH]
lokal Propensity score
lokal Colonic Neoplasms/surgery [MeSH]
lokal Colon cancer
lokal Long-term survivor
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-6987-705X|https://orcid.org/0000-0001-8004-4940|https://frl.publisso.de/adhoc/uri/Q2hhbmctQ2xhdWRlLCBKZW5ueQ==|https://orcid.org/0000-0002-8307-3197|https://orcid.org/0000-0002-6129-1572|https://orcid.org/0000-0001-9320-8684
1000 Hinweis
  • DeepGreen-ID: 24466a4305654a9ab4d90ef3a532f42d ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-11-17T23:20:25.819+0100
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