Childhood trauma and somatic and mental illness in adulthood: Findings of the NAKO health study

  1. Klinger-König, Johanna
  2. Erhardt, Angelika
  3. Streit, Fabian
  4. Völker, Maja P.
  5. Schulze, Matthias B.
  6. Keil, Thomas
  7. Fricke, Julia
  8. Castell, Stefanie
  9. Klett-Tammen, Carolina
  10. Pischon, Tobias
  11. Karch, André
  12. Teismann, Henning
  13. Michels, Karin
  14. Greiser, Karin Halina
  15. Becher, Heiko
  16. Karrasch, Stefan
  17. Ahrens, Wolfgang ORCID logo
  18. Meinke-Franze, Claudia
  19. Schipf, Sabine
  20. Mikolajczyk, Rafael
  21. Führer, Amand
  22. Brandes, Berit ORCID logo
  23. Schmidt, Börge
  24. Emmel, Carina
  25. Leitzmann, Michael
  26. Konzok, Julian
  27. Peters, Anette
  28. Obi, Nadia
  29. Brenner, Hermann
  30. Holleczek, Bernd
  31. Velásquez, Ilais Moreno
  32. Deckert, Jürgen
  33. Baune, Bernhard T.
  34. Rietschel, Marcella
  35. Berger, Klaus
  36. Grabe, Hans J.

WeightNameValue
1000 Titel
  • Childhood trauma and somatic and mental illness in adulthood: Findings of the NAKO health study
1000 Autor/in
  1. Klinger-König, Johanna |
  2. Erhardt, Angelika |
  3. Streit, Fabian |
  4. Völker, Maja P. |
  5. Schulze, Matthias B. |
  6. Keil, Thomas |
  7. Fricke, Julia |
  8. Castell, Stefanie |
  9. Klett-Tammen, Carolina |
  10. Pischon, Tobias |
  11. Karch, André |
  12. Teismann, Henning |
  13. Michels, Karin |
  14. Greiser, Karin Halina |
  15. Becher, Heiko |
  16. Karrasch, Stefan |
  17. Ahrens, Wolfgang |
  18. Meinke-Franze, Claudia |
  19. Schipf, Sabine |
  20. Mikolajczyk, Rafael |
  21. Führer, Amand |
  22. Brandes, Berit |
  23. Schmidt, Börge |
  24. Emmel, Carina |
  25. Leitzmann, Michael |
  26. Konzok, Julian |
  27. Peters, Anette |
  28. Obi, Nadia |
  29. Brenner, Hermann |
  30. Holleczek, Bernd |
  31. Velásquez, Ilais Moreno |
  32. Deckert, Jürgen |
  33. Baune, Bernhard T. |
  34. Rietschel, Marcella |
  35. Berger, Klaus |
  36. Grabe, Hans J. |
1000 Erscheinungsjahr 2024
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-01-12
1000 Erschienen in
1000 Quellenangabe
  • 121(1):1-8
1000 FRL-Sammlung
1000 Verlagsversion
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10916765/ |
  • https://doi.org/10.3238/arztebl.m2023.0225 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Childhood trauma is associated with somatic and mental illness in adulthood. The strength of the association varies as a function of age, sex, and type of trauma. Pertinent studies to date have mainly focused on individual diseases. In this study, we investigate the association between childhood trauma and a multiplicity of somatic and mental illnesses in adulthood. METHODS: Data from 156 807 NAKO Health Study participants were analyzed by means of logistic regressions, with adjustment for age, sex, years of education, and study site. The Childhood Trauma Screener differentiated between no/minor (n = 115 891) and moderate/severe childhood trauma (n = 40 916). The outcome variables were medical diagnoses of five somatic and two mental health conditions as stated in the clinical history. RESULTS: Persons with childhood trauma were more likely to bear a diagnosis of all of the studied conditions: cancer (odds ratio [OR] = 1.10; 95% confidence interval: [1.05; 1.15]), myocardial infarction (OR = 1.13 [1.03; 1.24]), diabetes (OR = 1.16, [1.10; 1.23]), stroke (OR = 1.35 [1.23; 1.48]), chronic obstructive pulmonary disease (OR = 1.45 [1.38; 1.52]), depression (OR = 2.36 [2.29; 2.43]), and anxiety disorders (OR = 2.08 [2.00; 2.17]). All of these associations were stronger in younger persons, regardless of the nature of childhood trauma. Differences between the sexes were observed only for some of these associations. CONCLUSION: Childhood trauma was associated with a higher probability of developing mental as well as somatic illness in adulthood. As childhood trauma is an element of individual history that the victim has little to no control over, and because the illnesses that can arise in adulthood in association with it are a heavy burden on the affected persons and on society, there is a need for research on these associations and for the development of preventive measures.
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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1000 Label
1000 Förderer
  1. Bundesministerium für Bildung und Forschung |
  2. Helmholtz-Gemeinschaft |
1000 Fördernummer
  1. 01ER1301A/B/C; 01ER1511D
  2. -
1000 Förderprogramm
  1. -
  2. -
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Bildung und Forschung |
    1000 Förderprogramm -
    1000 Fördernummer 01ER1301A/B/C; 01ER1511D
  2. 1000 joinedFunding-child
    1000 Förderer Helmholtz-Gemeinschaft |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6484062.rdf
1000 Erstellt am 2024-09-03T11:46:27.809+0200
1000 Erstellt von 266
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1000 Bearbeitet von 288
1000 Zuletzt bearbeitet 2024-09-20T13:06:00.150+0200
1000 Objekt bearb. Wed Sep 18 08:56:59 CEST 2024
1000 Vgl. frl:6484062
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  1. oai:frl.publisso.de:frl:6484062 |
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