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1000 Titel
  • Combined versus standalone XEN45 Gel Stent implantation in either phakic or pseudophakic patients: a case-matched study
1000 Autor/in
  1. Kiessling, David |
  2. Rennings, Corinna |
  3. Hild, Matthias |
  4. Lappas, Alexandra |
  5. Dietlein, Thomas Stefan |
  6. Roessler, Gernot Franz |
  7. Widder, Randolf |
1000 Verlag Springer Berlin Heidelberg
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-11-11
1000 Erschienen in
1000 Quellenangabe
  • 262(4):1253-1262
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00417-023-06283-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995041/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>To determine differing outcomes among either phakic or pseudophakic patients who received standalone XEN45 Gel Stent (Allergan, an AbbVie Company, CA, USA) implantation and patients who underwent combined surgery with phacoemulsification.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>This retrospective single-center study involved 180 eyes of 180 participants who underwent XEN45 Gel Stent implantation, of which 60 eyes received combined surgery with phacoemulsification (combined group). Standalone stent implantation was performed on 60 phakic (phakic group) and on 60 pseudophakic eyes (pseudophakic group). The groups were matched in a ratio of 1:1:1 based on multiple criteria. Successful surgery was defined by three scores: IOP at the longest follow-up of &lt; 21 mmHg (Score A) or &lt; 18 mmHg (Score B) and an IOP reduction &gt; 20% or IOP ≤ 15 mmHg and an IOP reduction ≥ 40% (Score C). In all scores, one open conjunctival revision was allowed, and additional repeat surgery was considered a failure.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>After an average follow-up time interval of 20.6 ± 12.6 months, there was a mean IOP-reduction by 37% among the entire cohort. Comparative analysis between the three groups did not show significant differences regarding postoperative IOP, postoperative medication score, side effects, revision rate, repeat surgery rate or success rate. A dysfunctional stent was detected in eight eyes (4%) during open conjunctival revision in 76 eyes.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>The clinical endpoints investigated did not differ significantly among either phakic or pseudophakic patients who received standalone stent implantation and patients who underwent combined surgery. However mean latency between primary stent implantation and first revision surgery after combined surgery was markedly shorter.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Stents [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Glaucoma
lokal Open-angle glaucoma
lokal Cataract surgery
lokal Glaucoma Drainage Implants [MeSH]
lokal Glaucoma incisional surgery
lokal Microstent
lokal MIGS
lokal Glaucoma, Open-Angle [MeSH]
lokal Intraocular Pressure [MeSH]
lokal XEN
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2llc3NsaW5nLCBEYXZpZA==|https://frl.publisso.de/adhoc/uri/UmVubmluZ3MsIENvcmlubmE=|https://frl.publisso.de/adhoc/uri/SGlsZCwgTWF0dGhpYXM=|https://frl.publisso.de/adhoc/uri/TGFwcGFzLCBBbGV4YW5kcmE=|https://frl.publisso.de/adhoc/uri/RGlldGxlaW4sIFRob21hcyBTdGVmYW4=|https://frl.publisso.de/adhoc/uri/Um9lc3NsZXIsIEdlcm5vdCBGcmFueg==|https://orcid.org/0000-0001-7487-1501
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    1000 Förderer Universitätsklinikum Köln |
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