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1000 Titel
  • Conserved host-pathogen interactions identify novel treatment options in betacoronavirus infections
1000 Autor/in
  1. Lukassen, Soeren |
  2. Eils, Roland |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-10
1000 Erschienen in
1000 Quellenangabe
  • 6(1):57
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41392-021-00480-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872823/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Hypoxia is an underlying pathophysiological condition of a variety of devastating diseases, including acute ischemic stroke (AIS). We are faced with limited therapeutic options for AIS patients, and even after successful restoration of cerebral blood flow, the poststroke mortality is still high. More basic research is needed to explain mortality after reperfusion and to develop adjunct neuroprotective therapies. Drosophila melanogaster (D.m.) is a suitable model to analyze hypoxia; however, little is known about the impacts of hypoxia and especially of the subsequent reperfusion injury on the behavior and survival of D.m. To address this knowledge gap, we subjected two wild-type D.m. strains (Canton-S and Oregon-R) to severe hypoxia (<0.3% O
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Research Highlight
lokal COVID-19 [MeSH]
lokal Humans [MeSH]
lokal Infectious diseases
lokal Host-Pathogen Interactions [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-7045-6327|https://frl.publisso.de/adhoc/uri/RWlscywgUm9sYW5k
1000 Hinweis
  • DeepGreen-ID: 681fb30a732346d5a200c81841c8c02f ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-04-26T15:08:48.821+0200
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1000 Zuletzt bearbeitet Sat Oct 14 10:44:13 CEST 2023
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  1. oai:frl.publisso.de:frl:6442630 |
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