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The novel GCK variant p.Val455Leu associated with hyperinsulinism is susceptible to allosteric activation and is conducive to weight gain and the development of diabetes

2021 . Langer, Sara | Waterstradt, Rica | Hillebrand, Georg | Santer, René | Baltrusch, Simone

Differences in the prevalence of erectile dysfunction between novel subgroups of recent-onset diabetes

2021 . Maalmi, Haifa | Herder, Christian | Bönhof, Gidon J. | Strassburger, Klaus | Zaharia, Oana Patricia | Rathmann, Wolfgang | Burkart, Volker | Szendroedi, Julia | Roden, Michael | Ziegler, Dan

The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells

Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle

2021 . Sarabhai, Theresia | Koliaki, Chrysi | Mastrototaro, Lucia | Kahl, Sabine | Pesta, Dominik | Apostolopoulou, Maria | Wolkersdorfer, Martin | Bönner, Anna C. | Bobrov, Pavel | Markgraf, Daniel F. | Herder, Christian | Roden, Michael

Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy

Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes

2020 . Ziegler, Dan | Strom, Alexander | Straßburger, Klaus | Knebel, Birgit | Bönhof, Gidon | Kotzka, Jörg | Szendroedi, Julia | Roden, Michael

Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes

2020 . Krause, Christin | Geißler, Cathleen | Tackenberg, Heidi | El Gammal, Alexander T. | Wolter, Stefan | Spranger, Joachim | Mann, Oliver | Lehnert, Hendrik | Kirchner, Henriette

Knockout of vascular smooth muscle EGF receptor in a mouse model prevents obesity-induced vascular dysfunction and renal damage in vivo

2020 . Stern, Christian | Schreier, Barbara | Nolze, Alexander | Rabe, Sindy | Mildenberger, Sigrid | Gekle, Michael

Temporal trends in diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes between 2006 and 2016: results from 13 countries in three continents

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