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Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A

2019 . Torres, Diogo | Hou, Xiaonan | Bale, Laurie | Heinzen, Ethan P. | Maurer, Matthew J. | Zanfagnin, Valentina | Oberg, Ann L. | Conover, Cheryl | Weroha, Saravut

Functional relevance of in vivo half antibody exchange of an IgG4 therapeutic antibody-drug conjugate

2018 . Herbener, Peter | Schönfeld, Kurt | König, Martin | Germer, Matthias | Przyborski, Jude M. | Bernöster, Katrin | Schüttrumpf, Jörg

Parallel PI3K, AKT and mTOR inhibition is required to control feedback loops that limit tumor therapy

2018 . Sathe, Anuja | Chalaud, Géraldine | Oppolzer, Immanuel | Wong, Kit Yeng | von Busch, Margarita | Schmid, Sebastian C. | Tong, Zhichao | Retz, Margitta | Gschwend, Juergen E. | Schulz, Wolfgang A. | Nawroth, Roman

A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics

2018 . Costa, Maria José | Kudaravalli, Jyothirmayee | Liu, Wen-Hui | Stock, Jeffrey | Kong, Sophanna | Liu, Shu-Hui

MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors

2018 . Juric, Vladi | O'Sullivan, Chris | Stefanutti, Erin | Kovalenko, Maria | Greenstein, Andrew | Barry-Hamilton, Vivian | Mikaelian, Igor | Degenhardt, Jeremiah | Yue, Peng | Smith, Victoria | Mikels-Vigdal, Amanda

T cell mediated immunity after combination therapy with intralesional PV-10 and blockade of the PD-1/PD-L1 pathway in a murine melanoma model

2018 . Liu, Hao | Weber, Amy | Morse, Jennifer | Kodumudi, Krithika | Scott, Ellen | Mullinax, John | Sarnaik, Amod A. | Pilon-Thomas, Shari

Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma

2017 . Takahashi, Yutaka | Yasui, Tomohiro | Tamari, Keisuke | Minami, Kazumasa | Otani, Keisuke | Isohashi, Fumiaki | Seo, Yuji | Kambe, Ryosuke | Koizumi, Masahiko | Ogawa, Kazuhiko

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

2017 . Wang, Feng | Wang, Liqing | Wu, Jian | Sokirniy, Ivan | Nguyen, Phuong | Bregnard, Thomas | Weinstock, Joseph | Mattern, Michael | Bezsonova, Irina | Hancock, Wayne W. | Kumar, Suresh

Combination of anti-L1 cell adhesion molecule antibody and gemcitabine or cisplatin improves the therapeutic response of intrahepatic cholangiocarcinoma

2017 . Cho, Seulki | Lee, Tae Sup | Song, In Ho | Kim, A-Ram | Lee, Yoon-Jin | Kim, Haejung | Hwang, Haein | Jeong, Mun Sik | Kang, Seung Goo | Hong, Hyo Jeong

Safety and antitumor activity of the anti–PD-1 antibody pembrolizumab in patients with advanced colorectal carcinoma

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