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Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition

2024 . Nath, Kavindra | Gupta, Pradeep K. | Basappa, Johnvesly | Wang, Shengchun | Sen, Neil | Lobello, Cosimo | Tomar, Jyoti S. | Shestov, Alexander A. | Orlovskiy, Stepan | Arias-Mendoza, Fernando | Rauert-Wunderlich, Hilka | Nelson, David S. | Glickson, Jerry D. | Wasik, Mariusz A.

INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer

2024 . Maxwell, Melissa | Yan, Dingxue | Rivest, Brianna | Boone, Andrew | Cardia, James | Noessner, Elfriede

Novel Vpx virus-like particles to improve cytarabine treatment response against acute myeloid leukemia

2024 . Nair, Ramya | Salinas-Illarena, Alejandro | Sponheimer, Monika | Wullkopf, Inès | Schreiber, Yannick | Côrte-Real, João Vasco | del Pozo Ben, Augusto | Marterer, Helena | Thomas, Dominique | Geisslinger, Gerd | Cinatl, Jindrich | Subklewe, Marion | Baldauf, Hanna-Mari

CRISPR/Cas9-mediated knock out of ITGB6 in human OSCC cells reduced migration and proliferation ability

2024 . Geyer, Maximilian | Geyer, Fabian | Reuning, Ute | Klapproth, Sarah | Wolff, Klaus-Dietrich | Nieberler, Markus

Targeting CXCR4/CXCL12 axis via [177Lu]Lu-DOTAGA.(SA.FAPi)2 with CXCR4 antagonist in triple-negative breast cancer

2024 . Bao, Guangfa | Wang, Ziqiang | Liu, Luoxia | Zhang, Buchuan | Song, Shuang | Wang, Dongdong | Cheng, Siyuan | Moon, Eu-Song | Roesch, Frank | Zhao, Jun | Yu, Bo | Zhu, Xiaohua

Miniaturized protein profiling permits targeted signaling pathway analysis in individual circulating tumor cells to improve personalized treatment

2024 . Rivandi, Mahdi | Franken, André | Yang, Liwen | Abramova, Anna | Stamm, Nadia | Eberhardt, Jens | Gierke, Berthold | Beer, Meike | Fehm, Tanja | Niederacher, Dieter | Pawlak, Michael | Neubauer, Hans

HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma

Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice

2024 . Mengoni, Miriam | Braun, Andreas Dominik | Seedarala, Sahithi | Bonifatius, Susanne | Kostenis, Evi | Schanze, Denny | Zenker, Martin | Tüting, Thomas | Gaffal, Evelyn

Illuminating Dark Chemical Matter Using the Cell Painting Assay

2024 . Pahl, Axel | Liu, Jie | PATIL, SOHAN | Rezaei Adariani, Soheila | Schölermann, Beate | Warmers, Jens | Bonowski, Jana | Koska, Sandra | Akbulut, Yasemin | Seitz, Carina | Sievers, Sonja | Ziegler, Slava | Waldmann, Herbert

Nanoformulation of dasatinib cannot overcome therapy resistance of pancreatic cancer cells with low LYN kinase expression

2024 . Kaul, Marilyn | Sanin, Ahmed Y. | Shi, Wenjie | Janiak, Christoph | Kahlert, Ulf Dietrich

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