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Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy

2021 . Wanior, Marek | Krämer, Andreas | Knapp, Stefan | Joerger, Andreas

Genome-wide DNA methylation analysis pre- and post-lenalidomide treatment in patients with myelodysplastic syndrome with isolated deletion (5q)

Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton

2021 . Adamus, Anna | Ali, Iftikhar | Vasileiadis, Vasileios | Al-Hileh, Luai | Lisec, Jan | Frank, Marcus | Seitz, Guido | Engel, Nadja

G-quadruplexes: a promising target for cancer therapy

2021 . Kosiol, Nils | Juranek, Stefan | Brossart, Peter | Heine, Annkristin | Paeschke, Katrin

A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy

2021 . Fischer, Nicolas | Seo, Ean-Jeong | Abdelfatah, Sara | Fleischer, Edmond | Klinger, Anette | Efferth, Thomas

The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia

2021 . Wellbrock, Jasmin | Behrmann, Lena | Muschhammer, Jana | Modemann, Franziska | Khoury, Kais | Brauneck, Franziska | Bokemeyer, Carsten | Campeau, Eric | Fiedler, Walter

Inhibitors of PD-1/PD-L1 and ERK1/2 impede the proliferation of receptor positive and triple-negative breast cancer cell lines

2021 . Bräutigam, Karen | Kabore-Wolff, Elodie | Hussain, Ahmad Fawzi | Polack, Stephan | Rody, Achim | Hanker, Lars | Köster, Frank

Novel chemotherapeutic agent FX-9 activates NF-κB signaling and induces G1 phase arrest by activating CDKN1A in a human prostate cancer cell line

2021 . Weiner, F. | Schille, J. T. | Koczan, D. | Wu, X.-F. | Beller, M. | Junghanss, C. | Hewicker-Trautwein, M. | Murua Escobar, H. | Nolte, I.

FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro

2020 . Mohamed, A. Allam | Thomsen, Andreas | Follo, Marie | Zamboglou, Costantinos | Bronsert, Peter | Mostafa, Hanan | Amen, Aber | Mekawy, Mohamed | Grosu, Anca L. | Brunner, Thomas

Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia

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