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Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas

2021 . Müller, Denise | Mazzeo, Paolo | Koch, Raphael | Bösherz, Mark-Sebastian | Welter, Stefan | von Hammerstein-Equord, Alexander | Hinterthaner, Marc | Cordes, Lucia | Belharazem, Djeda | Marx, Alexander | Ströbel, Philipp | Küffer, Stefan

BRAF V600E mutation is associated with aggressive features in papillary thyroid carcinomas ≤ 1.5 cm

2021 . Silver, Jennifer | Bogatchenko, Mariya | Pusztaszeri, Marc | Forest, Véronique-Isabelle | Hier, Michael P. | Yang, Ji Wei | Tamilia, Michael | Payne, Richard J.

Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis

2021 . Kobelt, Dennis | Perez Hernandez, Daniel | Fleuter, Claudia | Dahlmann, Mathias | Zincke, Fabian | Smith, Janice | Migotti, Rebekka | Popp, Oliver | Burock, Susen | Walther, Wolfgang | Dittmar, Gunnar | Mertins, Philipp | Stein, Ulrike

Serum S100B and LDH at Baseline and During Therapy Predict the Outcome of Metastatic Melanoma Patients Treated with BRAF Inhibitors

2021 . Gassenmaier, Maximilian | Lenders, Max M. | Forschner, Andrea | Leiter, Ulrike | Weide, Benjamin | Garbe, Claus | Eigentler, Thomas K. | Wagner, Nikolaus

Retroviral integrations contribute to elevated host cancer rates during germline invasion

2021 . McEwen, Gayle | Alquezar-Planas, David E. | Dayaram, Anisha | Gillett, Amber | Tarlinton, Rachael | Mongan, Nigel | Chappell, Keith J. | Henning, Joerg | Tan, Milton | Timms, Peter | Young, Paul R. | Roca, Alfred L. | Greenwood, Alex

EZHIP: a new piece of the puzzle towards understanding pediatric posterior fossa ependymoma

2021 . , | Camgöz, Aylin | Pfister, Stefan M. | Kool, Marcel

Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies

Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases

2021 . Zhang, Yi | Ma, Liyuan | Liu, Jie | Zhu, Huijuan | Lu, Lin | Deng, Kan | Ma, Wenbin | Pan, Hui | Wang, Renzhi | Yao, Yong

Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung

2021 . Lüdtke, Timo H. | Wojahn, Irina | Kleppa, Marc-Jens | Schierstaedt, Jasper | Christoffels, Vincent M. | Künzler, Patrick | Kispert, Andreas

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