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Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1

Mice Are Not Humans: The Case of p53

2021 . Fischer, Martin

p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): a mechanistic and correlative investigation into genetic and molecular characteristics

2021 . Diesing, Karoline | Ribback, Silvia | Winter, Stefan | Gellert, Manuela | Oster, Antonia M. | Stühler, Viktoria | Gläser, Eva | Adler, Frank | Hartwig, Christoph | Scharpf, Markus | Bedke, Jens | Burchardt, Martin | Schwab, Matthias | Lillig, Christopher H. | Kroeger, Nils

Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases

2021 . Zhang, Yi | Ma, Liyuan | Liu, Jie | Zhu, Huijuan | Lu, Lin | Deng, Kan | Ma, Wenbin | Pan, Hui | Wang, Renzhi | Yao, Yong

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53

Extent, pattern, and prognostic value of MGMT promotor methylation: does it differ between glioblastoma and IDH-wildtype/TERT-mutated astrocytoma?

2021 . Teske, Nico | Karschnia, Philipp | Weller, Jonathan | Siller, Sebastian | Dorostkar, Mario M. | Herms, Jochen | von Baumgarten, Louisa | Tonn, Joerg Christian | Thon, Niklas

p53 partial loss-of-function mutations sensitize to chemotherapy

2021 . Klimovich, Boris | Merle, Nastasja | Neumann, Michelle | Elmshäuser, Sabrina | Nist, Andrea | Mernberger, Marco | Kazdal, Daniel | Stenzinger, Albrecht | Timofeev, Oleg | Stiewe, Thorsten

Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis

2021 . Guerra, Gabriela Maria | May, Doreen | Kroll, Torsten | Koch, Philipp | Groth, Marco | Wang, Zhao-Qi | Li, Tangliang | Grigaravičius, Paulius

PTEN Hamartoma Tumor Syndrome: Skin Manifestations and Insights Into Their Molecular Pathogenesis

2021 . Innella, Giovanni | Bonora, Elena | Neri, Iria | Virdi, Annalucia | Guglielmo, Alba | Pradella, Laura Maria | Ceccarelli, Claudio | Amato, Laura Benedetta | Lanzoni, Anna | Miccoli, Sara | Gasparre, Giuseppe | Zuntini, Roberta | Turchetti, Daniela

PHF6 Mutations in Hematologic Malignancies

2021 . Kurzer, Jason H. | Weinberg, Olga K.

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