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Axitinib plus immune checkpoint inhibitor: evidence- and expert-based consensus recommendation for treatment optimisation and management of related adverse events

2020 . Grünwald, Viktor | Voss, Martin H. | Rini, Brian I. | Powles, Thomas | Albiges, Laurence | Giles, Rachel H. | Jonasch, Eric

T-type calcium channel inhibition restores sensitivity to MAPK inhibitors in de-differentiated and adaptive melanoma cells

2020 . Granados, Karol | Hüser, Laura | Federico, Aniello | Sachindra, Sachindra | Wolff, Gretchen | Hielscher, Thomas | Novak, Daniel | Madrigal-Gamboa, Verónica | Sun, Qian | Vierthaler, Marlene | Larribère, Lionel | Umansky, Viktor | Utikal, Jochen

Adaptive ERK signalling activation in response to therapy and in silico prognostic evaluation of EGFR-MAPK in HNSCC

2020 . Rong, Chao | Muller, Marie F. | Xiang, Fang | Jensen, Alexandra | Weichert, Wilko | Major, Gerald | Plinkert, Peter K. | Hess, Jochen | Affolter, Annette

CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms

2020 . Skowron, Margaretha A. | Vermeulen, Marieke | Winkelhausen, Anna | Becker, Teresa K. | Bremmer, Felix | Petzsch, Patrick | Schönberger, Stefan | Calaminus, Gabriele | Köhrer, Karl | Albers, Peter | Nettersheim, Daniel

Deep learning in cancer pathology: a new generation of clinical biomarkers

2020 . Echle, Amelie | Rindtorff, Niklas Timon | Brinker, Titus Josef | Luedde, Tom | Pearson, Alexander Thomas | Kather, Jakob Nikolas

Serine-dependent redox homeostasis regulates glioblastoma cell survival

2020 . Engel, Anna L. | Lorenz, Nadja I. | Klann, Kevin | Münch, Christian | Depner, Cornelia | Steinbach, Joachim P. | Ronellenfitsch, Michael W. | Luger, Anna-Luisa

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

2020 . Siddiqui, Mohammad Aarif | Gollavilli, Paradesi Naidu | Ramesh, Vignesh | Parma, Beatrice | Schwab, Annemarie | Vazakidou, Maria Eleni | Natesan, Ramakrishnan | Saatci, Ozge | Rapa, Ida | Bironzo, Paolo | Schuhwerk, Harald | Asangani, Irfan Ahmed | Sahin, Ozgur | Volante, Marco | Ceppi, Paolo

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