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Validation of putative biomarkers of furan exposure through quantitative analysis of furan metabolites in urine of F344 rats exposed to stable isotope labeled furan

2024 . Kalisch, C. | Reiter, M. | Krieger, M. | Wüst, L. | Klotz, C. | Dekant, R. | Lachenmeier, D. W. | Scherf-Clavel, O. | Mally, Angela

Utility of in vivo metabolomics to support read-across for UVCB substances under REACH

2024 . Kamp, H. | Kocabas, N. Aygun | Faulhammer, F. | Synhaeve, N. | Rushton, E. | Flick, B. | Giri, V. | Sperber, S. | Higgins, L. G. | Penman, M. G. | van Ravenzwaay, Bennard | Rooseboom, M.

Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice

Modular air–liquid interface aerosol exposure system (MALIES) to study toxicity of nanoparticle aerosols in 3D-cultured A549 cells in vitro

2024 . Küstner, M. J. | Eckstein, D. | Brauer, Dana | Mai, P. | Hampl, J. | Weise, F. | Schuhmann, B. | Hause, G. | Glahn, F. | Foth, H. | Schober, A.

Controversy on health-based guidance values for bisphenol A—the need of criteria for studies that serve as a basis for risk assessment

Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis

2024 . Jochum, Kristina | Miccoli, Andrea | Sommersdorf, Cornelia | Poetz, Oliver | Braeuning, Albert | Tralau, Tewes | Marx-Stoelting, Philip

Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food

Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans

2024 . Geci, René | Gadaleta, Domenico | de Lomana, Marina García | Ortega-Vallbona, Rita | Colombo, Erika | Serrano-Candelas, Eva | Paini, Alicia | Kuepfer, Lars | Schaller, Stephan

PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man

2024 . Lehmann, Anja | Geburek, Ina | Hessel-Pras, Stefanie | Enge, Anne-Margarethe | Mielke, Hans | Müller-Graf, Christine | Kloft, Charlotte | Hethey, Christoph

Escaping the cohort of concern: in vitro experimental evidence supports non-mutagenicity of N-nitroso-hydrochlorothiazide

2024 . Gandhi, Raj | Hickert, S. | Hoevelmann, Y. | Mee, C. D. | Schlingemann, Joerg | Adams, A. | Blanazs, Alexander | Simon, Stephanie | Elloway, J. | Rigger, Lukas | Teasdale, A. | Kent, Claire Victoria | Wright, L. | Doherty, A.

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