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Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo

2021 . Seiwert, Nina | Adam, Janine | Steinberg, Pablo | Wirtz, Stefan | Schwerdtle, Tanja | Adams-Quack, Petra | Hövelmeyer, Nadine | Kaina, Bernd | Foersch, Sebastian | Fahrer, Jörg

Prediction of the dose range for adverse neurological effects of amiodarone in patients from an in vitro toxicity test by in vitro–in vivo extrapolation

2021 . Algharably, Engi | Di Consiglio, Emma | Testai, Emanuela | Kreutz, Reinhold | Gundert-Remy, Ursula

A fast and reliable method for monitoring genomic instability in the model organism Caenorhabditis elegans

2021 . Nicolai, Merle Marie | Witt, Barbara | Hartwig, Andrea | Schwerdtle, Tanja | Bornhorst, Julia

A new perspective on calmodulin-regulated calcium and ROS homeostasis upon carbon black nanoparticle exposure

2021 . Verma, Nisha | Pink, Mario | Schmitz-Spanke, Simone

Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling

Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose

2021 . Hemmer, Selina | Wagmann, Lea | Meyer, Markus R.

New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite (“M-12”)

2021 . Schettgen, Thomas | Bertram, J. | Kraus, T.

The enzyme subunit SubA of Shiga toxin-producing E. coli strains demonstrates comparable intracellular transport and cytotoxic activity as the holotoxin SubAB in HeLa and HCT116 cells in vitro

2021 . Sessler, Katharina | Papatheodorou, Panagiotis | Wondany, Fanny | Krause, Maike | Noettger, Sabrina | Bernhard, Denise | Michaelis, Jens | Schmidt, Herbert | Barth, Holger

New aspects in snake venom toxicology

2021 . Bolt, Hermann M.

Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium

2021 . Probst, Stephanie | Fels, Johannes | Scharner, Bettina | Wolff, Natascha A. | Roussa, Eleni | van Swelm, Rachel | Lee, Wing-Kee | Thévenod, Frank

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