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Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers

2024 . Jessen, Marco | Gertzmann, Dörthe | Liss, Franziska | Zenk, Franziska | Bähner, Laura | Schöffler, Victoria | Schulte, Clemens | Maric, Hans Michael | Ade, Carsten | von Eyss, Bjoern | Gaubatz, Stefan

Recurrent DNMT3B rearrangements are associated with unfavorable outcome in dicentric (9;20)-positive pediatric BCP-ALL

Nonlinear DNA methylation trajectories in aging male mice

2024 . Olecka, Maja | van Bömmel, Alena | Best, Lena | Haase, Madlen | Foerste, Silke | Riege, Konstantin | Dost, Thomas | Flor, Stefano | Witte, Otto W. | Franzenburg, Sören | Groth, Marco | von Eyss, Bjoern | Kaleta, Christoph | Frahm, Christiane | Hoffmann, Steve

Genetic separation of chronic myeloid leukemia stem cells from normal hematopoietic stem cells at single-cell resolution

2023 . Chen, Yulin | Möbius, Susanne | Riege, Konstantin | Hoffmann, Steve | Hochhaus, Andreas | Ernst, Thomas | Rudolph, Karl Lenhard

Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer

2023 . Safrastyan, Aram | zu Siederdissen, Christian Höner | Wollny, Damian

The landscape of human p53‐regulated long non‐coding RNAs reveals critical host gene co‐regulation

2023 . Fischer, Martin | Riege, Konstantin | Hoffmann, Steve

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasms

2022 . Ernst, Philipp | Schnöder, Tina M. | Huber, Nicolas | Perner, Florian | Jayavelu, Ashok Kumar | Eifert, Theresa | Hsu, Chen-Jen | Tubío-Santamaría, Nuria | Crodel, Carl C. | Ungelenk, Martin | Huebner, Christian A. | Clement, Joachim H. | Hochhaus, Andreas | Heidel, Florian

Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

2021 . Freter, Rasmus | Falletta, Paola | Omrani, Omid | Rasa, Mahdi | Herbert, Katharine | Annunziata, Francesco | Minetti, Alberto | Krepelova, Anna | Adam, Lisa | Käppel, Sandra | Rüdiger, Tina | Wang, Zhao-Qi | Goding, Colin | neri, francesco

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