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Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines

2020 . Sklarz, L.-M. | Gladbach, Y. S. | Ernst, M. | Hamed, M. | Roolf, C. | Sender, S. | Beck, J. | Schütz, E. | Fischer, S. | Struckmann, S. | Junghanss, C. | Fuellen, G. | Murua Escobar, Hugo

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

Genotoxic and cytotoxic potential of methacrylate-based orthodontic adhesives

2020 . Taubmann, Andreas | Willershausen, Ines | Walter, Christian | Al-Maawi, Sarah | Kaina, Bernd | Gölz, Lina

BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses

2020 . Wang, Jiang | Li, Guo-Li | Ming, Sheng-Li | Wang, Chun-Feng | Shi, Li-Juan | Su, Bing-Qian | Wu, Hong-Tao | Zeng, Lei | Han, Ying-Qian | Liu, Zhong-Hu | Jiang, Da-Wei | Du, Yong-Kun | Li, Xiang-Dong | Zhang, Gai-Ping | Yang, Guo-Yu | Chu, Bei-Bei

Comparison of time and dose dependent gene expression and affected pathways in primary human fibroblasts after exposure to ionizing radiation

Long-term fate of etoposide-induced micronuclei and micronucleated cells in Hela-H2B-GFP cells

2020 . Reimann, Hauke | Stopper, Helga | Hintzsche, Henning

The repertoire of mutational signatures in human cancer

Inhibition of Apoptotic Pathways Improves DNA Integrity but Not Developmental Competence of Domestic Cat Immature Vitrified Oocytes

2020 . Colombo, Martina | Zahmel, Jennifer | Jänsch, Stefanie | Jewgenow, Katarina | Luvoni, Gaia Cecilia

Hepatotoxicity of pyrrolizidine alkaloids in rats in relation to human exposure

2020 . Bolt, Hermann M.

Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells

2020 . Hölzel, Bastian Niklas | Pfannkuche, Kurt Paul | Allner, Bernhard | Allner, Hans Thomas | Hescheler, Jürgen | Derichsweiler, Daniel | Hollert, Henner | Schiwy, Andreas | Brendt, Julia | Schaffeld, Michael | Froschauer, Alexander | Stahlschmidt-Allner, Petra

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