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Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

2020 . Knott, Maximilian M. L. | Hölting, Tilman L. B. | Ohmura, Shunya | Kirchner, Thomas | Cidre-Aranaz, Florencia | Grünewald, Thomas G. P.

High level of EZH2 expression is linked to high density of CD8-positive T-lymphocytes and an aggressive phenotype in renal cell carcinoma

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

2020 . Cortes Ciriano, Isidro | Lee, June-Koo | Xi, Ruibin | Jain, Dhawal | Jung, Youngsook L. | Yang, Lixing | Gordenin, Dmitry | Klimczak, Les | Zhang, Cheng-Zhong | Pellman, David S. | Park, Peter . PCAWG Structural Variation Working Group | PCAWG Consortium

EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

Epigenetics impacts upon prognosis and clinical management of choroidplexus tumors

2020 . Thomas, Christian | Metrock, Katie | Kordes, Uwe | Hasselblatt, Martin | Dhall, Girish

Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas

The role of fatal family history and mode of inheritance in prostate cancer for long-term outcomes following radical prostatectomy

2020 . Meissner, Valentin H. | Strüh, Jamila G. H. | Kron, Martina | Liesenfeld, Lea A. | Kranz, Stephanie | Gschwend, Jürgen E. | Herkommer, Kathleen

GATA binding protein 6 (GATA6) is co-amplified with PIK3CA in patients with esophageal adenocarcinoma and is linked to neoadjuvant therapy

2020 . Plum, Patrick Sven | Löser, Heike | Zander, Thomas | Essakly, Ahlem | Bruns, Christiane J. | Hillmer, Axel M. | Alakus, Hakan | Schröder, Wolfgang | Büttner, Reinhard | Gebauer, Florian | Quaas, Alexander

FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

Whole blood DNA methylation aging markers predict colorectal cancer survival: a prospective cohort study

2020 . Gao, Xin | Zhang, Yan | Boakye, Daniel | Li, Xiangwei | Chang-Claude, Jenny | Hoffmeister, Michael | Brenner, Hermann

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