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EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

2020 . Zhang, Xin | Zegar, Tim | Lucas, Anais | Morrison-Smith, Chevaun | Knox, Tatiana | French, Christopher A. | Knapp, Stefan | Müller-Knapp, Susanne | Siveke, Jens

Lymphocyte activation gene 3 (LAG3) protein expression on tumor-infiltrating lymphocytes in aggressive and TP53-mutated salivary gland carcinomas

2020 . Arolt, Christoph | Meyer, Moritz | Ruesseler, Vanessa | Nachtsheim, Lisa | Wuerdemann, Nora | Dreyer, Thomas | Gattenlöhner, Stefan | Wittekindt, Claus | Buettner, Reinhard | Quaas, Alexander | Klussmann, Jens Peter

Upregulated immuno-modulator PD-L1 in malignant peripheral nerve sheath tumors provides a potential biomarker and a therapeutic target

2020 . Farschtschi, Said | Kluwe, Lan | Park, Su-Jin | Oh, Su-Jun | Mah, Nancy | Mautner, Victor-Felix | Kurtz, Andreas

Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53

2020 . Fan, Kaiji | Spassova, Ivelina | Gravemeyer, Jan | Ritter, Cathrin | Horny, Kai | Lange, Anja | Gambichler, Thilo | Ødum, Niels | Schrama, David | Schadendorf, Dirk | Ugurel, Selma | Becker, Jürgen

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia

In cis TP53 and RAD51C pathogenic variants may predispose to sebaceous gland carcinomas

2020 . Le Duc, Diana | Hentschel, Julia | Neuser, Sonja | Stiller, Mathias | Meier, Carolin | Jäger, Elisabeth | Abou Jamra, Rami | Platzer, Konrad | Monecke, Astrid | Ziemer, Mirjana | Markovic, Aleksander | Bläker, Hendrik | Lemke, Johannes

Autoantibodies against P29ING4 are associated with complex regional pain syndrome

2020 . Baerlecken, Niklas | Gaulke, R. | Pursche, N. | Witte, T. | Karst, M | Bernateck, M.

RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice

2020 . , Antje | Woods, Michelle L. | Küster, Miriam M. | Walesch, Sara K. | Braun, Thomas | Boettger, Thomas | Dammann, Reinhard H.

Expression differences of miR-142-5p between treatment-naïve chronic myeloid leukemia patients responding and non-responding to imatinib therapy suggest a link to oncogenic ABL2, SRI, cKIT and MCL1 signaling pathways critical for development of therapy resistance

2020 . Klümper, Theresa | Bruckmueller, Henrike | Diewock, Tobias | Kaehler, Meike | Haenisch, Sierk | Pott, Christiane | Bruhn, Oliver | Cascorbi, Ingolf

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