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Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease

2020 . Key, Jana | Maletzko, Antonia | Kohli, Aneesha | Gispert, Suzana | Torres-Odio, Sylvia | Wittig, Ilka | Heidler, Juliana | Bárcena, Clea | López-Otín, Carlos | Lei, Yuanjiu | West, A. Phillip | Münch, Christian | Auburger, Georg

Immune landscape and a novel immunotherapy-related gene signature associated with clinical outcome in early-stage lung adenocarcinoma

2020 . , | Shi, Run | Zhao, Tianyu | Wang, Yanfang

Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

EndoPredict® in early hormone receptor-positive, HER2-negative breast cancer

2020 . Almstedt, Katrin | Mendoza, S. | Otto, M. | Battista, M. J. | Steetskamp, J. | Heimes, A. S. | Krajnak, S. | Poplawski, A. | Gerhold-Ay, A. | Hasenburg, A. | Denkert, C. | Schmidt, M.

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

2020 . Reischmann, Nadine | Andrieux, Geoffroy | Griffin, Ricarda | Reinheckel, Thomas | Boerries, Melanie | Brummer, Tilman

Cooperating, congenital neutropenia–associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs

2020 . Ritter, Malte | Klimiankou, Maksim | Klimenkova, Olga | Schambach, Axel | Hoffmann, Dirk | Schmidt, Amy | Kanz, Lothar | Link, Daniel C. | Welte, Karl | Skokowa, Julia

CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms

2020 . Skowron, Margaretha A. | Vermeulen, Marieke | Winkelhausen, Anna | Becker, Teresa K. | Bremmer, Felix | Petzsch, Patrick | Schönberger, Stefan | Calaminus, Gabriele | Köhrer, Karl | Albers, Peter | Nettersheim, Daniel

Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases

Microbially competent 3D skin: a test system that reveals insight into host–microbe interactions and their potential toxicological impact

2020 . Lemoine, Lisa | Dieckmann, Ralf | Al Dahouk, Sascha | Vincze, Szilvia | Luch, Andreas | Tralau, Tewes

Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBROb/Ob mice

2020 . Qiu, Jiedong | Albrecht, Thomas | Zhang, Shiqi | Hauske, Sibylle J. | Rodriguez-Niño, Angelica | Zhang, Xinmiao | Nosan, Darya | Pastene, Diego O. | Sticht, Carsten | Delatorre, Carolina | van Goor, Harry | Porubsky, Stefan | Krämer, Bernhard K. | Yard, Benito A.

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