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Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

A Multicentre, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of the S1P Receptor Agonist KRP203 in Patients with Moderately Active Refractory Ulcerative Colitis

2020 . Radeke, Heinfried | Stein, Jürgen | Van Assche, Gert | Rogler, Gerhard | Lakatos, Peter L. | Muellershausen, Florian | Moulin, Pierre | Jarvis, Philip | Colin, Laurence | Gergely, Peter | Kruis, Wolfgang

S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis

2020 . Weigel, Cynthia | Hüttner, Sören S. | Ludwig, Kristin | Krieg, Nadine | Hofmann, Susann | Schröder, Nathalie H. | Robbe, Linda | Kluge, Stefan | Nierhaus, Axel | Winkler, Martin S. | Rubio, Ignacio | von Maltzahn, Julia | Spiegel, Sarah | Gräler, Markus