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Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors

2021 . Delp, Johannes | Cediel-Ulloa, Andrea | Suciu, Ilinca | Kranaster, Petra | van Vugt-Lussenburg, Barbara MA | Munic Kos, Vesna | van der Stel, Wanda | Carta, Giada | Bennekou, Susanne Hougaard | Jennings, Paul | van de Water, Bob | Forsby, Anna | Leist, Marcel

Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons

2021 . Loser, Dominik | Hinojosa, Maria G. | Blum, Jonathan | Schaefer, Jasmin | Brüll, Markus | Johansson, Ylva | Suciu, Ilinca | Grillberger, Karin | Danker, Timm | Möller, Clemens | Gardner, Iain | Ecker, Gerhard F. | Bennekou, Susanne H. | Forsby, Anna | Kraushaar, Udo | Leist, Marcel

A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling

2021 . Klima, Stefanie | Brüll, Markus | Spreng, Anna-Sophie | Suciu, Ilinca | Falt, Tjalda | Schwamborn, Jens C. | Waldmann, Tanja | Karreman, Christiaan | Leist, Marcel

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds

Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling

Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury