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Optimization of sepsis therapy based on patient-specific digital precision diagnostics using next generation sequencing (DigiSep-Trial)—study protocol for a randomized, controlled, interventional, open-label, multicenter trial

2021 . Brenner, Thorsten | Skarabis, Annabell | Stevens, Philip | Axnick, Jennifer | Haug, Peter | Grumaz, Silke | Bruckner, Thomas | Luntz, Steffen | Witzke, Oliver | Pletz, Mathias W. | Ruprecht, Thomas M. | Marschall, Ursula | Altin, Sibel | Greiner, Wolfgang | Berger, Marc Moritz

Pharmacological Targeting of BMP6-SMAD Mediated Hepcidin Expression Does Not Improve the Outcome of Systemic Infections With Intra-Or Extracellular Gram-Negative Bacteria in Mice

2021 . Hoffmann, Alexander | de Souza, Lara Valente | Seifert, Markus | von Raffay, Laura | Haschka, David | Grubwieser, Philipp | Grander, Manuel | Mitterstiller, Anna-Maria | Nairz, Manfred | Poli, Maura | Weiss, Günter

The epidemiology of bloodstream infections and antimicrobial susceptibility patterns in Thuringia, Germany: a five-year prospective, state-wide surveillance study (AlertsNet)

2021 . Schöneweck, Franziska | Schmitz, Roland P. H. | Rißner, Florian | Scherag, André | Löffler, Bettina | Pletz, Mathias W. | Weis, Sebastian | Brunkhorst, Frank M. | Hagel, Stefan

Antibiotics in critically ill children—a narrative review on different aspects of a rational approach

2021 . Bruns, Nora | Dohna-Schwake, Christian