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A new class of 7-deazaguanine agents targeting autoimmune diseases: dramatic reduction of synovial fibroblast IL-6 production from human rheumatoid arthritis patients and improved performance against murine experimental autoimmune encephalomyelitis†

2024 . Cotter, Michelle | Quinn, Shauna M. | Fearon, Ursula | Ansboro, Sharon | Rakovic, Tatsiana | Southern, John | Kelly, Vincent | Connon, Stephen

Temporal Data Modeling Evaluation in Knowledge Graphs: A Healthcare Use Case

2024 . Hooshafza, Sepideh | Stephens, Gaye | Little, Mark | Yaman, Beyza

Zn(ii)-catalyzed asymmetric [3 + 2] cycloaddition of acyclic enones with azomethine ylides†

2024 . Kumar, Sundaravel Vivek | Olusegun, Jeremiah | Guiry, Patrick

Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

2024 . Greene, Chris | Connolly, Ruairi | Brennan, Declan | Laffan, Aoife | O'Keeffe, Eoin | Zaporojan, Lilia | O'Callaghan, Jeffrey | Thomson, Bennett | Connolly, Emma | Argue, Ruth | Martin-Loeches, Ignacio | Long, Aideen | Cheallaigh, Cliona Ni | Conlon, Niall | Doherty, Colin | Campbell, Matthew

Synthesis of C-glycoside analogues of isopropyl β-d-1-thiogalactopyranoside (IPTG) and 1-β-d-galactopyranosyl-2-methylpropane. Conformational analysis and evaluation as inhibitors of the lac repressor in E. coli and as galactosidase inhibitors†

2024 . Hever, Eoin | SANTHANAM, VENKATESAN | Alberi, Sherivan | Dhara, Ashis | Bols, Mikael | Nasheuer, Heinz Peter | Murphy, Paul

Catalytic stereoselective synthesis of cyclopentanones from donor–acceptor cyclopropanes and in situ-generated ketenes†

2024 . Mitra, Shubhanjan | Connolly, Sophie M. | Ayidi, Saud | Mondal, Mukulesh | Panda, Manashi | Kelly, Brian G. | Kerrigan, Nessan

Self-reducing precursors for aluminium metal thin films: evaluation of stable aluminium hydrides for vapor phase aluminium deposition†

2024 . Huster, Niklas | Mullins, Rita | Nolan, Michael | ,

Exploring therapy transport from implantable medical devices using experimentally informed computational methods

2024 . Trask, Lesley | Ward, Niamh | Tarpey, Ruth | Beatty, Rachel | Wallace, Eimear | O'Dwyer, Joanne | Ronan, William | Duffy, Garry P. | Dolan, Eimear

Synthesis and characterisation of antimicrobial metal–organic frameworks as multi-drug carriers†

2024 . Ahmed, Ahmed | Kelly, Aileen | Leonard, Dayle | Saleem, Waleed | Bezrukov, Andrey A. | Efthymiou, Constantinos G. | zaworotko, michael | tiana, davide | Boyd, Aoife | Papatriantafyllopoulou, Constantina