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Safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 685509, a soluble guanylyl cyclase activator, in healthy volunteers: Results from two randomized controlled trials

2024 . Wong, Diane | Seitz, Friedeborg | Bauer, Verena | Giessmann, Thomas | Schulze, Friedrich

Biotransformation and toxicokinetics of 2-phenoxyethanol after oral exposure in humans: a volunteer study

2024 . Eckert, Elisabeth | Jäger, Thomas | Hiller, Julia | Leibold, Edgar | Bader, Michael | Göen, Thomas

Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers

2024 . Rohr, Brit S. | Krohmer, Evelyn | Foerster, Kathrin Isabelle | Burhenne, Jürgen | Schulz, Martin | Blank, Antje | Mikus, Gerd | Haefeli, Walter E.

Ritlecitinib, a JAK3/TEC family kinase inhibitor, stabilizes active lesions and repigments stable lesions in vitiligo

2024 . Yamaguchi, Yuji | Peeva, Elena | Del Duca, Ester | Facheris, Paola | Bar, Jonathan | Shore, Ronald | Cox, Lori Ann | Sloan, Abigail | Thaci, Diamant | Ganesan, Anand | Han, George | Ezzedine, Khaled | Ye, Zhan | Guttman-Yassky, Emma

Disability and Adverse Effects of Oral Versus Long-Acting Injectable Antipsychotics in Schizophrenia-Spectrum and Bipolar Disorder: A Comparison Based on Data-Driven Taxonomy

2024 . Rodolico, Alessandro | Aprile, Sofia Francesca | Cutrufelli, Pierfelice | Privitera, Gabriele | Castellano, Sabrina | Concerto, Carmen | Furnari, Rosaria | Guerrera, Claudia Savia | MINEO, LUDOVICO | Platania, Giuseppe Alessio | Petralia, Antonino | Caraci, Filippo | Signorelli, Maria Salvina

Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies

Human metabolism and kinetics of the UV absorber 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV 328) after oral administration

2021 . Denghel, Heike | Hiller, Julia | Leibold, Edgar | Göen, Thomas

Indirect Comparison of Topiramate and Monoclonal Antibodies Against CGRP or Its Receptor for the Prophylaxis of Episodic Migraine: A Systematic Review with Meta-Analysis

2021 . Overeem, Lucas Hendrik | Raffaelli, Bianca | Mecklenburg, Jasper | Kelderman, Tim | Neeb, Lars | Reuter, Uwe

New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite (“M-12”)

2021 . Schettgen, Thomas | Bertram, J. | Kraus, T.

Diltiazem Prophylaxis for the Prevention of Atrial Fibrillation in Patients Undergoing Thoracoabdominal Esophagectomy: A Retrospective Cohort Study

2020 . Hochreiter, Marcel | Schmidt, Thomas | Siegler, Benedikt H. | Sisic, Leila | Schmidt, Karsten | Bruckner, Thomas | Müller-Stich, Beat P. | Diener, Markus K. | Weigand, Markus A. | Büchler, Markus W. | Busch, Cornelius J.

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