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Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Nonlinear DNA methylation trajectories in aging male mice

2024 . Olecka, Maja | van Bömmel, Alena | Best, Lena | Haase, Madlen | Foerste, Silke | Riege, Konstantin | Dost, Thomas | Flor, Stefano | Witte, Otto W. | Franzenburg, Sören | Groth, Marco | von Eyss, Bjoern | Kaleta, Christoph | Frahm, Christiane | Hoffmann, Steve

Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium

2023 . Garside, George | Sandoval, Madeline | Beronja, Slobodan | Rudolph, Karl Lenhard

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging

2023 . Schädel, Patrick | Czapka, Anna | Gebert, Nadja | Jacobsen, Ilse D. | Ori, Alessandro | Werz, Oliver

Evolutionary paths to mammalian longevity through the lens of gene expression

2023 . Işıldak, Ulaş | Dönertaş, Handan Melike

Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol

2023 . Avraamidou, Elina | Nöthel, Moritz | Danisch, Melina | Bindila, Laura | Schmidt, Susanne V. | Lutz, Beat | Nickenig, Georg | Jehle, Julian

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

De novo genome assembly resolving repetitive structures enables genomic analysis of 35 European Mycoplasmopsis bovis strains

2023 . Triebel, Sandra | Sachse, Konrad | Weber, Michael | Heller, Martin | Diezel, Celia | Hölzer, Martin | Schnee, Christiane | Marz, Manja

IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration

Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasms

2022 . Ernst, Philipp | Schnöder, Tina M. | Huber, Nicolas | Perner, Florian | Jayavelu, Ashok Kumar | Eifert, Theresa | Hsu, Chen-Jen | Tubío-Santamaría, Nuria | Crodel, Carl C. | Ungelenk, Martin | Huebner, Christian A. | Clement, Joachim H. | Hochhaus, Andreas | Heidel, Florian

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